Search Results - "Weir, Alison J"

Characterization of a Structurally Intact in Situ Lung Model and Comparison of Naphthalene Protein Adducts Generated in This Model vs Lung Microsomes by Lin, Ching Yu, Isbell, Margaret A, Morin, Dexter, Boland, Bridget C, Salemi, Michelle R, Jewell, William T, Weir, Alison J, Fanucchi, Michelle V, Baker, Gregory L, Plopper, Charles G, Buckpitt, Alan R

“…Airway epithelial cells are a susceptible site for injury by ambient air toxicants such as naphthalene that undergo P450-dependent metabolic activation. The…”
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Smooth muscle development during postnatal growth of distal bronchioles in infant rhesus monkeys by Tran, Mai-Uyen T, Weir, Alison J, Fanucchi, Michelle V, Murphy, April E, Van Winkle, Laura S, Evans, Michael J, Smiley-Jewell, Suzette M, Miller, Lisa, Schelegle, Edward S, Gershwin, Laurel J, Hyde, Dallas M, Plopper, Charles G

“…1 Department of Anatomy, Physiology, and Cell Biology, 2 Department of Pathology, Microbiology, and Immunology, and 3 California National Primate Research…”
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Three-Dimensional Mapping of Ozone-Induced Acute Cytotoxicity in Tracheobronchial Airways of Isolated Perfused Rat Lung by Postlethwait, Edward M, Joad, Jessie P, Hyde, Dallas M, Schelegle, Edward S, Bric, John M, Weir, Alison J, Putney, Leialoha F, Wong, Viviana J, Velsor, Leonard W, Plopper, Charles G

“…Acute lung injury induced by reactive oxygen gases such as ozone (O(3)) is focal and site-selective. To define patterns of acute epithelial injury along…”
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Relationship of Inhaled Ozone Concentration to Acute Tracheobronchial Epithelial Injury, Site-specific Ozone Dose, and Glutathione Depletion in Rhesus Monkeys by Plopper, Charles G, Hatch, Gary E, Wong, Viviana, Duan, Xiuchen, Weir, Alison J, Tarkington, Brian K, Devlin, Robert B, Becker, Suzanne, Buckpitt, A. R

“…Acute pulmonary epithelial injury produced by short-term exposure to ozone varies by site within the tracheobronchial tree. To test whether this variability is…”
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Effect of Respiratory Pattern on Ozone Injury to the Airways of Isolated Rat Lungs by Joad, Jesse P., Bric, John M., Weir, Alison J., Putney, Lei, Hyde, Dallas M., Postlethwait, Edward M., Plopper, Charles G.

“…Ozone stimulates the “defensive” C-fibers in the lungs, changing breathing pattern to rapid and shallow. We hypothesized that when ozone is administered to the…”
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Acute Injury to Differentiating Clara Cells in Neonatal Rabbits Results in Age-Related Failure of Bronchiolar Epithelial Repair by Smiley-Jewell, Suzette M., Liu, Frank J., Weir, Alison J., Plopper, Charles G.

“…Nonciliated bronchiolar (Clara) cells are progenitor cells during lung development. During differentiation, they have a heightened injury susceptibility to…”
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Neonatal Clara cell toxicity by 4-ipomeanol alters bronchiolar organization in adult rabbits by Smiley-Jewell, S M, Nishio, S J, Weir, A J, Plopper, C G

“…Nonciliated bronchiolar (Clara) cells metabolize environmental toxicants, are progenitor cells during development, and differentiate postnatally. Because…”
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Smooth muscle development during postnatal growth of distal bronchioles in infant rhesus monkeys. Commentary by TRAN, Mai-Uyen T, WEIR, Alison J, HYDE, Dallas M, PLOPPER, Charles G, SIECK, Gary C, FANUCCHI, Michelle V, MURPHY, April E, VAN WINKLE, Laura S, EVANS, Michael J, SMILEY-JEWELL, Suzette M, MILLER, Lisa, SCHELEGLE, Edward S, GERSHWIN, Laurel J

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Differentiation of tracheal epithelium during fetal lung maturation in the rhesus monkey Macaca mulatta by Plopper, C G, Alley, J L, Weir, A J

“…Of the eight categories of epithelial cells identified in pulmonary conducting airways, four are found in the trachea of adult primates: basal, mucous goblet,…”
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Tracheal submucosal gland development in the rhesus monkey, Macaca mulatta: ultrastructure and histochemistry by Plopper, C G, Weir, A J, Nishio, S J, Cranz, D L, St George, J A

“…The submucosal glands are thought to be the primary source of the mucus overlying the primate trachea and conducting airways. This study characterizes the…”
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Cytochrome P450 2E1 in Rat Tracheobronchial Airways: Response to Ozone Exposure by Watt, Katherine C., Plopper, Charles G., Weir, Alison J., Tarkington, Brian, Buckpitt, Alan R.

“…The distal trachea and centriacinus of the lung are primary sites of acute injury during short-term ozone exposure; long-term exposure yields cells in these…”
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Ultrastructural morphometric characterization of alveolar type II cells of perinatal sheep: a comparison with adults by Lakritz, J, Weir, A J, Mariassy, A T, Kendall, J Z, Plopper, C G

“…The quantitative morphologic changes in alveolar type II cells during the perinatal period were characterized morphometrically in the lungs of fetal lambs at…”
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