Search Results - "Weinstock, P H"

Dendritic Location of Neural BC1 RNA by Tiedge, Henri, Fremeau, Robert T., Weinstock, Peter H., Arancio, Ottavio, Brosius, Jurgen

“…In nerve cells, a specialized protein synthetic machinery is thought to operate in local compartments of dendrites, in particular beneath synaptic junctions,…”
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Lipoprotein lipase expression exclusively in liver. A mouse model for metabolism in the neonatal period and during cachexia by Merkel, M, Weinstock, P H, Chajek-Shaul, T, Radner, H, Yin, B, Breslow, J L, Goldberg, I J

“…Lipoprotein lipase (LPL), the rate-limiting enzyme in triglyceride hydrolysis, is normally not expressed in the liver of adult humans and animals. However,…”
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Decreased HDL cholesterol levels but normal lipid absorption, growth, and feeding behavior in apolipoprotein A-IV knockout mice by Weinstock, P H, Bisgaier, C L, Hayek, T, Aalto-Setala, K, Sehayek, E, Wu, L, Sheiffele, P, Merkel, M, Essenburg, A D, Breslow, J L

“…To determine the physiological role of apolipoprotein (apo) A-IV, knockout mice were created by gene targeting in embryonic stem cells. In apoA-IV knockout…”
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Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apoC-III transgenic mice by Aalto-Setälä, K, Weinstock, P H, Bisgaier, C L, Wu, L, Smith, J D, Breslow, J L

“…We previously showed that human apoC-III expression in transgenic mice causes hypertriglyceridemia due to the accumulation of enlarged very low density…”
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Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice by Levak-Frank, S, Radner, H, Walsh, A, Stollberger, R, Knipping, G, Hoefler, G, Sattler, W, Weinstock, P H, Breslow, J L, Zechner, R

“…In extrahepatic tissues lipoprotein lipase (LPL) hydrolyzes triglycerides thereby generating FFA for tissue uptake and metabolism. To study the effects of…”
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Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase by Weinstock, P.H, Levak-Frank, S, Hudgins, L.C, Radner, H, Friedman, J.M, Zechner, R, Breslow, J.L

“…Lipoprotein lipase (LPL) is the rate-limiting enzyme for the import of triglyceride-derived fatty acids by muscle, for utilization, and adipose tissue (AT),…”
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Induced mutant mouse lines that express lipoprotein lipase in cardiac muscle, but not in skeletal muscle and adipose tissue, have normal plasma triglyceride and high-density lipoprotein-cholesterol levels by Levak-Frank, S, Hofmann, W, Weinstock, P.H, Radner, H, Sattler, W, Breslow, J.L, Zechner, R

“…The tissue-specific expression of lipoprotein lipase (LPL) in adipose tissue (AT), skeletal muscle (SM), and cardiac muscle (CM) is rate-limiting for the…”
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Deficient Heme and Globin Synthesis in Embryonic Stem Cells Lacking the Erythroid-Specific δ-Aminolevulinate Synthase Gene by Harigae, Hideo, Suwabe, Naruyoshi, Weinstock, Peter H., Nagai, Mayumi, Fujita, Hiroyoshi, Yamamoto, Masayuki, Sassa, Shigeru

“…The erythroid-specific isoform of δ-aminolevulinate synthase (ALAS-E) catalyzes the first step of heme biosynthesis in erythroid cells, and ALAS-E gene…”
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Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice by Levak-Frank, S, Radner, H, Walsh, A, Stollberger, R, Knipping, G, Hoefler, G, Sattler, W, Weinstock, P H, Breslow, J L, Zechner, R

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Branch capture reactions : effect of recipient structure by WEINSTOCK, P. H, WETMUR, J. G

“…Branch capture reactions (BCR) contain two DNA species: (i) a recipient restriction fragment terminating in an overhang and (ii) a displacer-linker duplex…”
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Lipoprotein lipase expression level influences tissue clearance of chylomicron retinyl ester by Van Bennekum, A.M, Kako, Y, Weinstock, P.H, Harrison, E.H, Deckelbaum, R.J, Goldberg, I.J, Blaner, W.S

“…Approximately 25% of postprandial retinoid is cleared from the circulation by extrahepatic tissues. Little is known about physiologic factors important to this…”
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Induced Mutant Mice Expressing Lipoprotein Lipase Exclusively in Muscle Have Subnormal Triglycerides yet Reduced High Density Lipoprotein Cholesterol Levels in Plasma by Levak-Frank, Sanja, Weinstock, Peter H., Hayek, Tony, Verdery, Roy, Hofmann, Wolfgang, Ramakrishnan, Rajasekhar, Sattler, Wolfgang, Breslow, Jan L., Zechner, Rudolf

“…To determine the contribution of muscle lipoprotein lipase (LPL) to lipoprotein metabolism, induced mutant mice were generated that express human LPL…”
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Branch capture reactions : displacers derived from asymmetric PCR by WONG, D. M, WEINSTOCK, P. H, WETMUR, J. G

“…Branch capture reactions (BCR) contain three DNA species: (i) a recipient restriction fragment terminating in an overhang, (ii) a displacer strand containing…”
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Lipoprotein lipase regulates Fc receptor-mediated phagocytosis by macrophages maintained in glucose-deficient medium by Yin, B, Loike, J D, Kako, Y, Weinstock, P H, Breslow, J L, Silverstein, S C, Goldberg, I J

“…During periods of intense activity such as phagocytosis, macrophages are thought to derive most of their energy from glucose metabolism under both aerobic and…”
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Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes by Weinstock, P H, Bisgaier, C L, Aalto-Setälä, K, Radner, H, Ramakrishnan, R, Levak-Frank, S, Essenburg, A D, Zechner, R, Breslow, J L

“…Lipoprotein lipase (LPL)-deficient mice have been created by gene targeting in embryonic stem cells. At birth, homozygous knockout pups have threefold higher…”
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Deficient Heme and Globin Synthesis in Embryonic Stem Cells Lacking the Erythroid-Specific δ-Aminolevulinate Synthase Gene by Harigae, Hideo, Suwabe, Naruyoshi, Weinstock, Peter H., Nagai, Mayumi, Fujita, Hiroyoshi, Yamamoto, Masayuki, Sassa, Shigeru

“…The erythroid-specific isoform of δ-aminolevulinate synthase (ALAS-E) catalyzes the first step of heme biosynthesis in erythroid cells, and ALAS-E gene…”
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