Search Results - "Weinstein, Michael M"

Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein-Binding Protein 1 Plays a Critical Role in the Lipolytic Processing of Chylomicrons by Beigneux, Anne P., Davies, Brandon S.J., Gin, Peter, Weinstein, Michael M., Farber, Emily, Qiao, Xin, Peale, Franklin, Bunting, Stuart, Walzem, Rosemary L., Wong, Jinny S., Blaner, William S., Ding, Zhi-Ming, Melford, Kristan, Wongsiriroj, Nuttaporn, Shu, Xiao, de Sauvage, Fred, Ryan, Robert O., Fong, Loren G., Bensadoun, André, Young, Stephen G.

“…The triglycerides in chylomicrons are hydrolyzed by lipoprotein lipase (LpL) along the luminal surface of the capillaries. However, the endothelial cell…”
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GPIHBP1, an endothelial cell transporter for lipoprotein lipase by Young, Stephen G., Davies, Brandon S.J., Voss, Constance V., Gin, Peter, Weinstein, Michael M., Tontonoz, Peter, Reue, Karen, Bensadoun, André, Fong, Loren G., Beigneux, Anne P.

“…Interest in lipolysis and the metabolism of triglyceride-rich lipoproteins was recently reignited by the discovery of severe hypertriglyceridemia…”
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Heme Oxygenase-1 Expression in Macrophages Plays a Beneficial Role in Atherosclerosis by Orozco, Luz D, Kapturczak, Matthias H, Barajas, Berenice, Wang, Xuping, Weinstein, Michael M, Wong, Jack, Deshane, Jessy, Bolisetty, Subhashini, Shaposhnik, Zory, Shih, Diana M, Agarwal, Anupam, Lusis, Aldons J, Araujo, Jesus A

“…Heme oxygenase (HO-1) is the rate-limiting enzyme in the catabolism of heme, which leads to the generation of biliverdin, iron, and carbon monoxide. It has…”
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Mice Expressing Mutant Trpv4 Recapitulate the Human TRPV4 Disorders by Weinstein, Michael M, Tompson, Stuart W, Chen, Yuqing, Lee, Brendan, Cohn, Daniel H

“…ABSTRACT Activating mutations in transient receptor potential vanilloid family member 4 (Trpv4) are known to cause a spectrum of skeletal dysplasias ranging…”
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Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia by Olivecrona, Gunilla, Ehrenborg, Ewa, Semb, Henrik, Makoveichuk, Elena, Lindberg, Anna, Hayden, Michael R., Gin, Peter, Davies, Brandon S.J., Weinstein, Michael M., Fong, Loren G., Beigneux, Anne P., Young, Stephen G., Olivecrona, Thomas, Hernell, Olle

“…We investigated a family from northern Sweden in which three of four siblings have congenital chylomicronemia. LPL activity and mass in pre- and postheparin…”
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Highly Conserved Cysteines within the Ly6 Domain of GPIHBP1 Are Crucial for the Binding of Lipoprotein Lipase by Beigneux, Anne P., Gin, Peter, Davies, Brandon S.J., Weinstein, Michael M., Bensadoun, André, Fong, Loren G., Young, Stephen G.

“…GPIHBP1, a glycosylphosphatidylinositol-anchored endothelial cell protein of the lymphocyte antigen 6 (Ly6) family, binds lipoprotein lipase (LPL) avidly and…”
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Chylomicronemia Elicits Atherosclerosis in Mice—Brief Report by Weinstein, Michael M, Yin, Liya, Tu, Yiping, Wang, Xuping, Wu, Xiaohui, Castellani, Lawrence W, Walzem, Rosemary L, Lusis, Aldons J, Fong, Loren G, Beigneux, Anne P, Young, Stephen G

“…OBJECTIVE—The risk of atherosclerosis in the setting of chylomicronemia has been a topic of debate. In this study, we examined susceptibility to…”
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The Acidic Domain of GPIHBP1 Is Important for the Binding of Lipoprotein Lipase and Chylomicrons by Gin, Peter, Yin, Liya, Davies, Brandon S.J., Weinstein, Michael M., Ryan, Robert O., Bensadoun, André, Fong, Loren G., Young, Stephen G., Beigneux, Anne P.

“…GPIHBP1, a glycosylphosphatidylinositol-anchored endothelial cell protein of the lymphocyte antigen 6 (Ly6) family, plays a key role in the lipolysis of…”
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Assessing the Role of the Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1) Three-finger Domain in Binding Lipoprotein Lipase by Beigneux, Anne P., Davies, Brandon S.J., Tat, Shelly, Chen, Jenny, Gin, Peter, Voss, Constance V., Weinstein, Michael M., Bensadoun, André, Pullinger, Clive R., Fong, Loren G., Young, Stephen G.

“…Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) is an endothelial cell protein that transports lipoprotein lipase…”
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Early Hepatic Insulin Resistance Precedes the Onset of Diabetes in Obese C57BLKS-db/db Mice by DAVIS, Richard C, CASTELLANI, Lawrence W, PETERFY, Miklós, HOSSEINI, Maryam, BEN-ZEEV, Osnat, MAO, Hui Z, WEINSTEI, Michael M, DAE YOUNG JUNG, JUN, John Y, KIM, Jason K, LUSIS, Aldons J

“…To identify metabolic derangements contributing to diabetes susceptibility in the leptin receptor-deficient obese C57BLKS/J-db/db (BKS-db) mouse strain. Young…”
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Apolipoprotein AII Is a Regulator of Very Low Density Lipoprotein Metabolism and Insulin Resistance by Castellani, Lawrence W., Nguyen, Cara N., Charugundla, Sarada, Weinstein, Michael M., Doan, Chau X., Blaner, William S., Wongsiriroj, Nuttaporn, Lusis, Aldons J.

“…Apolipoprotein AII (apoAII) transgenic (apoAIItg) mice exhibit several traits associated with the insulin resistance (IR) syndrome, including IR, obesity, and…”
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Abnormal Patterns of Lipoprotein Lipase Release into the Plasma in GPIHBP1-deficient Mice by Weinstein, Michael M., Yin, Liya, Beigneux, Anne P., Davies, Brandon S.J., Gin, Peter, Estrada, Kristine, Melford, Kristan, Bishop, Joseph R., Esko, Jeffrey D., Dallinga-Thie, Geesje M., Fong, Loren G., Bensadoun, André, Young, Stephen G.

“…GPIHBP1-deficient mice (Gpihbp1–/–) exhibit severe chylomicronemia. GPIHBP1 is located within capillaries of muscle and adipose tissue, and expression of…”
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Unexpected Expression Pattern for Glycosylphosphatidylinositol-anchored HDL-binding Protein 1 (GPIHBP1) in Mouse Tissues Revealed by Positron Emission Tomography Scanning by Olafsen, Tove, Young, Stephen G., Davies, Brandon S.J., Beigneux, Anne P., Kenanova, Vania E., Voss, Constance, Young, Glen, Wong, Koon-Pong, Barnes, Richard H., Tu, Yiping, Weinstein, Michael M., Nobumori, Chika, Huang, Sung-Cheng, Goldberg, Ira J., Bensadoun, André, Wu, Anna M., Fong, Loren G.

“…Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1), a GPI-anchored endothelial cell protein, binds lipoprotein lipase…”
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Dead Name, and: Trans People of the Past by Weinstein, Michael M

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Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase by Beigneux, Anne P., Gin, Peter, Davies, Brandon S.J., Weinstein, Michael M., Bensadoun, André, Ryan, Robert O., Fong, Loren G., Young, Stephen G.

“…GPIHBP1 is a glycosylphosphatidylinositol-anchored protein in the lymphocyte antigen 6 (Ly-6) family that recently was identified as a platform for the…”
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GPIHBP1 Is Responsible for the Entry of Lipoprotein Lipase into Capillaries by Davies, Brandon S.J., Beigneux, Anne P., Barnes, Richard H., Tu, Yiping, Gin, Peter, Weinstein, Michael M., Nobumori, Chika, Nyrén, Rakel, Goldberg, Ira, Olivecrona, Gunilla, Bensadoun, André, Young, Stephen G., Fong, Loren G.

“…The lipolytic processing of triglyceride-rich lipoproteins by lipoprotein lipase (LPL) is the central event in plasma lipid metabolism, providing lipids for…”
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Significantly reduced CCR5-tropic HIV-1 replication in vitro in cells from subjects previously immunized with Vaccinia Virus by Weinstein, Raymond S, Weinstein, Michael M, Alibek, Kenneth, Bukrinsky, Michael I, Brichacek, Beda

“…At present, the relatively sudden appearance and explosive spread of HIV throughout Africa and around the world beginning in the 1950s has never been…”
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Chylomicronemia With a Mutant GPIHBP1 (Q115P) That Cannot Bind Lipoprotein Lipase by Beigneux, Anne P, Franssen, Remco, Bensadoun, André, Gin, Peter, Melford, Kristan, Peter, Jorge, Walzem, Rosemary L, Weinstein, Michael M, Davies, Brandon S.J, Kuivenhoven, Jan A, Kastelein, John J.P, Fong, Loren G, Dallinga-Thie, Geesje M, Young, Stephen G

“…OBJECTIVE—GPIHBP1 is an endothelial cell protein that binds lipoprotein lipase (LPL) and chylomicrons. Because GPIHBP1 deficiency causes chylomicronemia in…”
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Palmoplantar Keratoderma along with Neuromuscular and Metabolic Phenotypes in Slurp1-Deficient Mice by Adeyo, Oludotun, Allan, Bernard B., Barnes, Richard H., Goulbourne, Chris N., Tatar, Angelica, Tu, Yiping, Young, Lorraine C., Weinstein, Michael M., Tontonoz, Peter, Fong, Loren G., Beigneux, Anne P., Young, Stephen G.

“…Mutations in SLURP1 cause mal de Meleda, a rare palmoplantar keratoderma (PPK). SLURP1 is a secreted protein that is expressed highly in keratinocytes but has…”
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Impaired Development of Atherosclerosis in Hyperlipidemic Ldlr−/− and ApoE−/− Mice Transplanted With Abcg1−/− Bone Marrow by Baldán, Ángel, Pei, Liming, Lee, Richard, Tarr, Paul, Tangirala, Rajendra K, Weinstein, Michael M, Frank, Joy, Li, Andrew C, Tontonoz, Peter, Edwards, Peter A

“…OBJECTIVE—The lungs of Abcg1 mice accumulate macrophage foam cells that contain high levels of unesterified and esterified cholesterol, consistent with a role…”
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