Search Results - "Weinstein, J J"

Deficits in striatal dopamine release in cannabis dependence by van de Giessen, E, Weinstein, J J, Cassidy, C M, Haney, M, Dong, Z, Ghazzaoui, R, Ojeil, N, Kegeles, L S, Xu, X, Vadhan, N P, Volkow, N D, Slifstein, M, Abi-Dargham, A

“…Most drugs of abuse lead to a general blunting of dopamine release in the chronic phase of dependence, which contributes to poor outcome. To test whether…”
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Pathway-Specific Dopamine Abnormalities in Schizophrenia by Weinstein, Jodi J, Chohan, Muhammad O, Slifstein, Mark, Kegeles, Lawrence S, Moore, Holly, Abi-Dargham, Anissa

“…Abstract In light of the clinical evidence implicating dopamine in schizophrenia and the prominent hypotheses put forth regarding alterations in dopaminergic…”
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Quantum squeezing of motion in a mechanical resonator by Wollman, E. E., Lei, C. U., Weinstein, A. J., Suh, J., Kronwald, A., Marquardt, F., Clerk, A. A., Schwab, K. C.

“…According to quantum mechanics, a harmonic oscillator can never be completely at rest. Even in the ground state, its position will always have fluctuations,…”
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Generation of a Nonhuman Primate Model of Severe Combined Immunodeficiency Using Highly Efficient Genome Editing by Sato, Kenya, Oiwa, Ryo, Kumita, Wakako, Henry, Rachel, Sakuma, Tetsushi, Ito, Ryoji, Nozu, Ryoko, Inoue, Takashi, Katano, Ikumi, Sato, Kengo, Okahara, Norio, Okahara, Junko, Shimizu, Yoshihisa, Yamamoto, Masafumi, Hanazawa, Kisaburo, Kawakami, Takao, Kametani, Yoshie, Suzuki, Ryuji, Takahashi, Takeshi, Weinstein, Edward J., Yamamoto, Takashi, Sakakibara, Yasubumi, Habu, Sonoko, Hata, Jun-ichi, Okano, Hideyuki, Sasaki, Erika

“…Recent advances in genome editing have facilitated the generation of nonhuman primate (NHP) models, with potential to unmask the complex biology of human…”
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A Perceptual Inference Mechanism for Hallucinations Linked to Striatal Dopamine by Cassidy, Clifford M., Balsam, Peter D., Weinstein, Jodi J., Rosengard, Rachel J., Slifstein, Mark, Daw, Nathaniel D., Abi-Dargham, Anissa, Horga, Guillermo

“…Hallucinations, a cardinal feature of psychotic disorders such as schizophrenia, are known to depend on excessive striatal dopamine. However, an underlying…”
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Neuromelanin-sensitive MRI as a noninvasive proxy measure of dopamine function in the human brain by Cassidy, Clifford M., Zucca, Fabio A., Girgis, Ragy R., Baker, Seth C., Weinstein, Jodi J., Sharp, Madeleine E., Bellei, Chiara, Valmadre, Alice, Vanegas, Nora, Kegeles, Lawrence S., Brucato, Gary, Kang, Un Jung, Sulzer, David, Zecca, Luigi, Abi-Dargham, Anissa, Horga, Guillermo

“…Neuromelanin-sensitive MRI (NM-MRI) purports to detect the content of neuromelanin (NM), a product of dopamine metabolism that accumulates with age in dopamine…”
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Analytic solution of the SEIR epidemic model via asymptotic approximant by Weinstein, Steven J., Holland, Morgan S., Rogers, Kelly E., Barlow, Nathaniel S.

“…An analytic solution is obtained to the SEIR Epidemic Model. The solution is created by constructing a single second-order nonlinear differential equation in…”
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Quantum Nondemolition Measurement of a Quantum Squeezed State Beyond the 3 dB Limit by Lei, C U, Weinstein, A J, Suh, J, Wollman, E E, Kronwald, A, Marquardt, F, Clerk, A A, Schwab, K C

“…We use a reservoir engineering technique based on two-tone driving to generate and stabilize a quantum squeezed state of a micron-scale mechanical oscillator…”
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Computational design and molecular dynamics simulations suggest the mode of substrate binding in ceramide synthases by Zelnik, Iris D., Mestre, Beatriz, Weinstein, Jonathan J., Dingjan, Tamir, Izrailov, Stav, Ben-Dor, Shifra, Fleishman, Sarel J., Futerman, Anthony H.

“…Until now, membrane-protein stabilization has relied on iterations of mutations and screening. We now validate a one-step algorithm, mPROSS, for stabilizing…”
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Targeted genome modification in mice using zinc-finger nucleases by Carbery, Iara D, Ji, Diana, Harrington, Anne, Brown, Victoria, Weinstein, Edward J, Liaw, Lucy, Cui, Xiaoxia

“…Homologous recombination-based gene targeting using Mus musculus embryonic stem cells has greatly impacted biomedical research. This study presents a powerful…”
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Mechanically detecting and avoiding the quantum fluctuations of a microwave field by Suh, J., Weinstein, A. J., Lei, C. U., Wollman, E. E., Steinke, S. K., Meystre, P., Clerk, A. A., Schwab, K. C.

“…Quantum fluctuations of the light field used for continuous position detection produce stochastic back-action forces and ultimately limit the sensitivity. To…”
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Association between serum retinol and overall and cause-specific mortality in a 30-year prospective cohort study by Huang, Jiaqi, Weinstein, Stephanie J., Yu, Kai, Männistö, Satu, Albanes, Demetrius

“…How retinol as a clinical indicator of vitamin A status is related to long-term mortality is unknown. Here we report the results of a prospective analysis…”
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National Psoriasis Foundation COVID-19 Task Force guidance for management of psoriatic disease during the pandemic: Version 2—Advances in psoriatic disease management, COVID-19 vaccines, and COVID-19 treatments by Gelfand, Joel M., Armstrong, April W., Bell, Stacie, Anesi, George L., Blauvelt, Andrew, Calabrese, Cassandra, Dommasch, Erica D., Feldman, Steven R., Gladman, Dafna, Kircik, Leon, Lebwohl, Mark, Lo Re, Vincent, Martin, George, Merola, Joseph F., Scher, Jose U., Schwartzman, Sergio, Treat, James R., Van Voorhees, Abby S., Ellebrecht, Christoph T., Fenner, Justine, Ocon, Anthony, Syed, Maha N., Weinstein, Erica J., Gondo, George, Heydon, Sue, Koons, Samantha, Ritchlin, Christopher T.

“…To update guidance regarding the management of psoriatic disease during the COVID-19 pandemic. The task force (TF) includes 18 physician voting members with…”
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Genome-wide association study of circulating vitamin D levels by Ahn, Jiyoung, Yu, Kai, Stolzenberg-Solomon, Rachael, Simon, K. Claire, McCullough, Marjorie L., Gallicchio, Lisa, Jacobs, Eric J., Ascherio, Alberto, Helzlsouer, Kathy, Jacobs, Kevin B., Li, Qizhai, Weinstein, Stephanie J., Purdue, Mark, Virtamo, Jarmo, Horst, Ronald, Wheeler, William, Chanock, Stephen, Hunter, David J., Hayes, Richard B., Kraft, Peter, Albanes, Demetrius

“…The primary circulating form of vitamin D, 25-hydroxy-vitamin D [25(OH)D], is associated with multiple medical outcomes, including rickets, osteoporosis,…”
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Metabolomic profile of prostate cancer-specific survival among 1812 Finnish men by Huang, Jiaqi, Zhao, Bin, Weinstein, Stephanie J, Albanes, Demetrius, Mondul, Alison M

“…Abstract Background Abnormal metabolism and perturbations in metabolic pathways play significant roles in the development and progression of prostate cancer;…”
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Directed evolution of novel adeno-associated viruses for therapeutic gene delivery by Bartel, M A, Weinstein, J R, Schaffer, D V

“…Gene therapy vectors based on adeno-associated virus (AAV) are currently in clinical trials for numerous disease targets, such as muscular dystrophy,…”
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Observation and Interpretation of Motional Sideband Asymmetry in a Quantum Electromechanical Device by Weinstein, A. J., Lei, C. U., Wollman, E. E., Suh, J., Metelmann, A., Clerk, A. A., Schwab, K. C.

“…Quantum electromechanical systems offer a unique opportunity to probe quantum noise properties in macroscopic devices, properties that ultimately stem from…”
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Rational design of cationic lipids for siRNA delivery by Semple, Sean C, Akinc, Akin, Chen, Jianxin, Sandhu, Ammen P, Mui, Barbara L, Cho, Connie K, Sah, Dinah W Y, Stebbing, Derrick, Crosley, Erin J, Yaworski, Ed, Hafez, Ismail M, Dorkin, J Robert, Qin, June, Lam, Kieu, Rajeev, Kallanthottathil G, Wong, Kim F, Jeffs, Lloyd B, Nechev, Lubomir, Eisenhardt, Merete L, Jayaraman, Muthusamy, Kazem, Mikameh, Maier, Martin A, Srinivasulu, Masuna, Weinstein, Michael J, Chen, Qingmin, Alvarez, Rene, Barros, Scott A, De, Soma, Klimuk, Sandra K, Borland, Todd, Kosovrasti, Verbena, Cantley, William L, Tam, Ying K, Manoharan, Muthiah, Ciufolini, Marco A, Tracy, Mark A, de Fougerolles, Antonin, MacLachlan, Ian, Cullis, Pieter R, Madden, Thomas D, Hope, Michael J

“…We adopted a rational approach to design cationic lipids for use in formulations to deliver small interfering RNA (siRNA). Starting with the ionizable cationic…”
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Stress Adapted Mollusca and Nematoda Exhibit Convergently Expanded Hsp70 and AIG1 Gene Families by Guerin, Megan N., Weinstein, Deborah J., Bracht, John R.

“…We recently sequenced the genome of the first subterrestrial metazoan, the nematode Halicephalobus mephisto. A central finding was a dramatic expansion of…”
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Serum metabolomic profile of hair dye use by Lim, Jung-eun, Huang, Jiaqi, Weinstein, Stephanie J., Parisi, Dominick, Mӓnnistö, Satu, Albanes, Demetrius

“…The International Agency for Research on Cancer reported that some chemicals in hair dyes are probably carcinogenic to those exposed to them occupationally…”
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