Search Results - "Weinshenker, Brian G."

Neuromyelitis Spectrum Disorders by Weinshenker, Brian G., MD, Wingerchuk, Dean M., MD

“…Abstract The understanding of neuromyelitis optica spectrum disorder (NMOSD) has evolved substantially since its initial description over a century ago. The…”
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Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines by Filippi, Massimo, Preziosa, Paolo, Banwell, Brenda L, Barkhof, Frederik, Ciccarelli, Olga, De Stefano, Nicola, Geurts, Jeroen J G, Paul, Friedemann, Reich, Daniel S, Toosy, Ahmed T, Traboulsee, Anthony, Wattjes, Mike P, Yousry, Tarek A, Gass, Achim, Lubetzki, Catherine, Weinshenker, Brian G, Rocca, Maria A

“…MRI has improved the diagnostic work-up of multiple sclerosis, but inappropriate image interpretation and application of MRI diagnostic criteria contribute to…”
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Glial fibrillary acidic protein immunoglobulin G as biomarker of autoimmune astrocytopathy: Analysis of 102 patients by Flanagan, Eoin P., Hinson, Shannon R., Lennon, Vanda A., Fang, Boyan, Aksamit, Allen J., Morris, P. Pearse, Basal, Eati, Honorat, Josephe A., Alfugham, Nora B., Linnoila, Jenny J., Weinshenker, Brian G., Pittock, Sean J., McKeon, Andrew

“…Objective A novel autoimmune central nervous system (CNS) disorder with glial fibrillary acidic protein (GFAP)‐IgG as biomarker was recently characterized…”
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Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls by Chen, Jun, Chia, Nicholas, Kalari, Krishna R., Yao, Janet Z., Novotna, Martina, Paz Soldan, M. Mateo, Luckey, David H., Marietta, Eric V., Jeraldo, Patricio R., Chen, Xianfeng, Weinshenker, Brian G., Rodriguez, Moses, Kantarci, Orhun H., Nelson, Heidi, Murray, Joseph A., Mangalam, Ashutosh K.

“…Multiple sclerosis (MS) is an immune-mediated disease, the etiology of which involves both genetic and environmental factors. The exact nature of the…”
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Association Between Tumor Necrosis Factor Inhibitor Exposure and Inflammatory Central Nervous System Events by Kunchok, Amy, Aksamit, Jr, Allen J, Davis, 3rd, John M, Kantarci, Orhun H, Keegan, B Mark, Pittock, Sean J, Weinshenker, Brian G, McKeon, Andrew

“…Tumor necrosis factor (TNF) inhibitors are common therapies for certain autoimmune diseases, such as rheumatoid arthritis. An association between TNF inhibitor…”
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The emerging relationship between neuromyelitis optica and systemic rheumatologic autoimmune disease by Wingerchuk, Dean M, Weinshenker, Brian G

“…Neuromyelitis optica (NMO) and NMO spectrum disorders (NMOSD) are associated with autoantibodies that target aquaporin-4 and, in many cases, multiple other…”
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Epidemiology of Neuromyelitis Optica Spectrum Disorder and Its Prevalence and Incidence Worldwide by Hor, Jyh Yung, Asgari, Nasrin, Nakashima, Ichiro, Broadley, Simon A., Leite, M. Isabel, Kissani, Najib, Jacob, Anu, Marignier, Romain, Weinshenker, Brian G., Paul, Friedemann, Pittock, Sean J., Palace, Jacqueline, Wingerchuk, Dean M., Behne, Jacinta M., Yeaman, Michael R., Fujihara, Kazuo

“…Neuromyelitis optica spectrum disorder (NMOSD) is an uncommon inflammatory disease of the central nervous system, manifesting clinically as optic neuritis,…”
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Atypical inflammatory demyelinating syndromes of the CNS by Hardy, Todd A, Dr, Reddel, Stephen W, PhD, Barnett, Michael H, PhD, Palace, Jacqueline, DM, Lucchinetti, Claudia F, Prof, Weinshenker, Brian G, Prof

“…Summary Atypical inflammatory demyelinating syndromes are rare disorders that differ from multiple sclerosis owing to unusual clinical or MRI findings or poor…”
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Eculizumab in AQP4-IgG-positive relapsing neuromyelitis optica spectrum disorders: an open-label pilot study by Pittock, Sean J, Dr, Lennon, Vanda A, PhD, McKeon, Andrew, MD, Mandrekar, Jay, PhD, Weinshenker, Brian G, MD, Lucchinetti, Claudia F, MD, O'Toole, Orna, MD, Wingerchuk, Dean M, Dr

“…Summary Background Complement activation after binding of an IgG autoantibody to aquaporin 4 (AQP4) is thought to be a major determinant of CNS inflammation…”
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Comparison of MRI Lesion Evolution in Different Central Nervous System Demyelinating Disorders by Sechi, Elia, Krecke, Karl N., Messina, Steven A., Buciuc, Marina, Pittock, Sean J., Chen, John J., Weinshenker, Brian G., Lopez-Chiriboga, A. Sebastian, Lucchinetti, Claudia F., Zalewski, Nicholas L., Tillema, Jan Mendelt, Kunchok, Amy, Monaco, Salvatore, Morris, Padraig P., Fryer, James P., Nguyen, Adam, Greenwood, Tammy, Syc-Mazurek, Stephanie B., Keegan, B. Mark, Flanagan, Eoin P.

“…There are few studies comparing lesion evolution across different CNS demyelinating diseases, yet knowledge of this may be important for diagnosis and…”
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Epidemiology of aquaporin-4 autoimmunity and neuromyelitis optica spectrum by Flanagan, Eoin P., Cabre, Philippe, Weinshenker, Brian G., Sauver, Jennifer St, Jacobson, Debra J., Majed, Masoud, Lennon, Vanda A., Lucchinetti, Claudia F., McKeon, Andrew, Matiello, Marcelo, Kale, Nilifur, Wingerchuk, Dean M., Mandrekar, Jay, Sagen, Jessica A., Fryer, James P., Robinson, Angala Borders, Pittock, Sean J.

“…Objective Neuromyelitis optica (NMO) and its spectrum disorders (NMOSD) are inflammatory demyelinating diseases (IDDs) with a specific biomarker,…”
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Discriminating long myelitis of neuromyelitis optica from sarcoidosis by Flanagan, Eoin P., Kaufmann, Timothy J., Krecke, Karl N., Aksamit, Allen J., Pittock, Sean J., Keegan, B. Mark, Giannini, Caterina, Weinshenker, Brian G.

“…Objective To compare longitudinally extensive myelitis in neuromyelitis optica spectrum disorders (NMOSD) and spinal cord sarcoidosis (SCS). Methods We…”
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Short myelitis lesions in aquaporin-4-IgG-positive neuromyelitis optica spectrum disorders by Flanagan, Eoin P, Weinshenker, Brian G, Krecke, Karl N, Lennon, Vanda A, Lucchinetti, Claudia F, McKeon, Andrew, Wingerchuk, Dean M, Shuster, Elizabeth A, Jiao, Yujuan, Horta, Erika S, Pittock, Sean J

“…Short transverse myelitis (STM; <3 vertebral segments) is considered noncharacteristic of neuromyelitis optica (NMO) spectrum disorders (NMOSDs)…”
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Characteristics of Spontaneous Spinal Cord Infarction and Proposed Diagnostic Criteria by Zalewski, Nicholas L, Rabinstein, Alejandro A, Krecke, Karl N, Brown, Jr, Robert D, Wijdicks, Eelco F M, Weinshenker, Brian G, Kaufmann, Timothy J, Morris, Jonathan M, Aksamit, Allen J, Bartleson, J D, Lanzino, Giuseppe, Blessing, Melissa M, Flanagan, Eoin P

“…Spinal cord infarction (SCI) is often disabling, and the diagnosis can be challenging without an inciting event (eg, aortic surgery). Patients with a…”
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The spectrum of neuromyelitis optica by Wingerchuk, Dean M, MD, Lennon, Vanda A, PhD, Lucchinetti, Claudia F, MD, Pittock, Sean J, MD, Weinshenker, Brian G, MD

“…Summary Neuromyelitis optica (also known as Devic's disease) is an idiopathic, severe, demyelinating disease of the central nervous system that preferentially…”
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Updated estimate of AQP4-IgG serostatus and disability outcome in neuromyelitis optica by Jiao, Yujuan, Fryer, James P., Lennon, Vanda A., Jenkins, Sarah M., Quek, Amy M.L., Smith, Carin Y., McKeon, Andrew, Costanzi, Chiara, Iorio, Raffaele, Weinshenker, Brian G., Wingerchuk, Dean M., Shuster, Elizabeth A., Lucchinetti, Claudia F., Pittock, Sean J.

“…OBJECTIVE:To 1) determine, using contemporary recombinant antigen–based assays, the aquaporin-4 (AQP4)–immunoglobulin G (IgG) detection rate in sequential sera…”
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Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria" by Polman, Chris H., Reingold, Stephen C., Edan, Gilles, Filippi, Massimo, Hartung, Hans-Peter, Kappos, Ludwig, Lublin, Fred D., Metz, Luanne M., McFarland, Henry F., O'Connor, Paul W., Sandberg-Wollheim, Magnhild, Thompson, Alan J., Weinshenker, Brian G., Wolinsky, Jerry S.

“…New diagnostic criteria for multiple sclerosis integrating magnetic resonance image assessment with clinical and other paraclinical methods were introduced in…”
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Frequency of demyelinating disease activity following immune checkpoint inhibitor cancer immunotherapy by Hasan, Shemonti, Zorio, Onilia, Keegan, B. Mark, Weinshenker, Brian G., Flanagan, Eoin P., Tobin, W. Oliver, Kantarci, Orhun H., Toledano, Michel, Pittock, Sean J., Lopez-Chiriboga, Sebastian, Zekeridou, Anastasia, Valencia-Sanchez, Cristina

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A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis by Lennon, Vanda A, Wingerchuk, Dean M, Kryzer, Thomas J, Pittock, Sean J, Lucchinetti, Claudia F, Fujihara, Kazuo, Nakashima, Ichiro, Weinshenker, Brian G

“…Neuromyelitis optica is an inflammatory demyelinating disease with generally poor prognosis that selectively targets optic nerves and spinal cord. It is…”
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Aquaporin-4 and MOG autoantibody discovery in idiopathic transverse myelitis epidemiology by Sechi, Elia, Shosha, Eslam, Williams, Jonathan P, Pittock, Sean J, Weinshenker, Brian G, Keegan, B Mark, Zalewski, Nicholas L, Lopez-Chiriboga, Alfonso Sebastian, Jitprapaikulsan, Jiraporn, Flanagan, Eoin P

“…OBJECTIVEDiagnostic criteria from 2002 classify transverse myelitis (TM) as idiopathic or disease associated but predate the discovery of aquaporin-4…”
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