Search Results - "Weingarten, Jens"
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Amyloid precursor proteins are constituents of the presynaptic active zone
Published in Journal of neurochemistry (01-10-2013)“…The amyloid precursor protein (APP) and its mammalian homologs, APLP1, APLP2, have been allocated to an organellar pool residing in the Golgi apparatus and in…”
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The proteome of the presynaptic active zone from mouse brain
Published in Molecular and cellular neuroscience (01-03-2014)“…Neurotransmitter release as well as the structural and functional dynamics of the presynaptic active zone is controlled by proteinaceous components. Here we…”
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Measuring the Beam Energy in Proton Therapy Facilities Using ATLAS IBL Pixel Detectors
Published in Instruments (Basel) (01-11-2022)“…The accurate measurement of the beam range in the frame of quality assurance (QA) is a requirement for clinical use of a proton therapy machine. Conventionally…”
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APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone
Published in PLoS computational biology (01-04-2016)“…The hallmarks of Alzheimer's disease (AD) are characterized by cognitive decline and behavioral changes. The most prominent brain region affected by the…”
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Amyloid precursor protein knockout diminishes synaptic vesicle proteins at the presynaptic active zone in mouse brain
Published in Current Alzheimer research (01-12-2014)“…The amyloid precursor protein (APP) has previously been allocated to an organellar pool residing in the Golgi apparatus and in endosomal compartments, and in…”
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6
The Proteome of the Murine Presynaptic Active Zone
Published in Proteomes (24-04-2014)“…The proteome of the presynaptic active zone controls neurotransmitter release and the short- and long-term structural and functional dynamics of the nerve…”
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Regional Specializations of the PAZ Proteomes Derived from Mouse Hippocampus, Olfactory Bulb and Cerebellum
Published in Proteomes (13-05-2015)“…Neurotransmitter release as well as structural and functional dynamics at the presynaptic active zone (PAZ) comprising synaptic vesicles attached to the…”
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Deep TL: progress of a machine learning aided personal dose monitoring system
Published in Radiation protection dosimetry (24-05-2023)“…Abstract Personal dosemeters using thermoluminescence detectors can provide information about the irradiation event beyond the pure dose estimation, which is…”
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Fast and accurate dose predictions for novel radiotherapy treatments in heterogeneous phantoms using conditional 3D‐UNet generative adversarial networks
Published in Medical physics (Lancaster) (01-05-2022)“…Purpose Novel radiotherapy techniques like synchrotron X‐ray microbeam radiation therapy (MRT) require fast dose distribution predictions that are accurate at…”
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Characterisation, simulation and test beam data analysis of stitched passive CMOS strip sensors
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (01-04-2024)“…In the passive CMOS Strips Project, strip sensors were designed at the University of Bonn and produced by LFoundry in 150 nm technology, with an additional…”
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Characterisation and simulation of stitched CMOS strip sensors
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (01-07-2024)“…In high-energy physics, there is a need to investigate alternative silicon sensor concepts that offer cost-efficient, large-area coverage. Sensors based on…”
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Evaluation of passive CMOS strip sensors
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (11-09-2022)“…Silicon sensors will continue to be the central tracking elements for upcoming particle physics detectors. They will have to cover large areas and thus be a…”
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13
The synaptic proteome
Published in Cell and tissue research (01-01-2015)“…Synapses are focal hot spots for signal transduction and plasticity in the brain. A synapse comprises an axon terminus, the presynapse, the synaptic cleft…”
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APP-A Novel Player within the Presynaptic Active Zone Proteome
Published in Frontiers in molecular neuroscience (20-02-2017)“…The amyloid precursor protein (APP) was discovered in the 1980s as the precursor protein of the amyloid A4 peptide. The amyloid A4 peptide, also known as…”
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Experimental consolidation and absolute measurement of the $$^\text {nat}$$C(p,x)$$^{11}$$C nuclear activation cross section at 100 MeV for particle therapy physics
Published in The European physical journal. A, Hadrons and nuclei (01-08-2021)“…Abstract The $$^\text {nat}$$ nat C(p,x) $$^{11}$$ 11 C reaction has been discussed in detail in the past [EXFOR database, Otuka et al. (Nuclear Data Sheets…”
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Results from the commissioning of the ATLAS pixel detector with cosmics data
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (11-05-2010)“…The ATLAS pixel detector consists of three barrel layers and three disk-layers in the endcaps, comprising a total of 80 million pixel cells. Commissioning for…”
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Measurement of nuclear activation cross sections of protons on natural carbon for proton beam energies between 100 and 220 MeV
Published in Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms (01-09-2019)“…In this work, we present measurements of nuclear activation cross sections from carbon. Carbon can be used for proton fluence calculation in proton therapy by…”
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Accurate and Fast Deep Learning Dose Prediction for a Preclinical Microbeam Radiation Therapy Study Using Low-Statistics Monte Carlo Simulations
Published in Cancers (04-04-2023)“…Microbeam radiation therapy (MRT) utilizes coplanar synchrotron radiation beamlets and is a proposed treatment approach for several tumor diagnoses that…”
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Towards using secondary gamma-rays from proton-induced radioactivation of titanium implants for off-line field verification
Published in Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms (01-04-2021)“…This experimental study investigates the radioactivation of titanium during proton therapy. Titanium is a commonly used material for implants. Because of its…”
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Experimental consolidation and absolute measurement of the natC(p,x)11C nuclear activation cross section at 100 MeV for particle therapy physics
Published in The European physical journal. A, Hadrons and nuclei (2021)“…The nat C(p,x) 11 C reaction has been discussed in detail in the past [EXFOR database, Otuka et al. (Nuclear Data Sheets 120:272–276, 2014)]. However, measured…”
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