Search Results - "Weingart, Jon"
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Impact of COVID-19 on an Academic Neurosurgery Department: The Johns Hopkins Experience
Published in World neurosurgery (01-07-2020)“…Coronavirus disease 2019 (COVID-19) is a disruptive pandemic that has continued to test the limits of health care system capacities. It is important to…”
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Identifying Recurrent Malignant Glioma after Treatment Using Amide Proton Transfer-Weighted MR Imaging: A Validation Study with Image-Guided Stereotactic Biopsy
Published in Clinical cancer research (15-01-2019)“…To quantify the accuracy of amide proton transfer-weighted (APTw) MRI for identifying active glioma after treatment via radiographically guided stereotactic…”
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Establishing percent resection and residual volume thresholds affecting survival and recurrence for patients with newly diagnosed intracranial glioblastoma
Published in Neuro-oncology (Charlottesville, Va.) (01-01-2014)“…Surgery is first-line therapy for glioblastoma, and there is evidence that gross total resection is associated with improved survival. Gross total resection,…”
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Independent association of extent of resection with survival in patients with malignant brain astrocytoma
Published in Journal of neurosurgery (01-01-2009)“…With recent advances in the adjuvant treatment of malignant brain astrocytomas, it is increasingly debated whether extent of resection affects survival. In…”
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Multiple resections for patients with glioblastoma: prolonging survival
Published in Journal of neurosurgery (01-04-2013)“…Glioblastoma is the most common and aggressive type of primary brain tumor in adults. These tumors recur regardless of intervention. This propensity to recur…”
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6
Association of surgically acquired motor and language deficits on overall survival after resection of glioblastoma multiforme
Published in Neurosurgery (01-09-2009)“…Balancing the benefits of extensive tumor resection with the consequence of potential postoperative deficits remains a challenge in malignant astrocytoma…”
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A systematic review and meta-analysis of supratotal versus gross total resection for glioblastoma
Published in Journal of neuro-oncology (01-07-2020)“…Purpose Due to the infiltrative nature of glioblastoma (GBM) outside of the contrast-enhancing region on MRI, there is interest in exploring supratotal…”
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Independent association of extent of resection with survival in patients with malignant brain astrocytoma : Clinical article
Published in Journal of neurosurgery (2009)“…Object With recent advances in the adjuvant treatment of malignant brain astrocytomas, it is increasingly debated whether extent of resection affects survival…”
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Amide proton transfer-weighted magnetic resonance image-guided stereotactic biopsy in patients with newly diagnosed gliomas
Published in European journal of cancer (1990) (01-09-2017)“…Pathological assessment using World Health Organization (WHO) criteria is the gold standard for diagnosis of gliomas. However, the accuracy of diagnosis is…”
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Extent of Surgical Resection is Independently Associated with Survival in Patients with Hemispheric Infiltrating Low-grade Gliomas
Published in Neurosurgery (01-10-2008)“…ABSTRACT OBJECTIVE It remains unknown whether the extent of surgical resection affects survival or disease progression in patients with supratentorial…”
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Surgical outcomes for older patients with glioblastoma multiforme: preoperative factors associated with decreased survival: Clinical article
Published in Journal of neurosurgery (01-03-2011)“…As the population ages, the incidence of glioblastoma multiforme (GBM) among older patients (age > 65 years) will increase. Older patients, unlike their…”
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Supratentorial Glioblastoma Multiforme: The Role of Surgical Resection Versus Biopsy Among Older Patients
Published in Annals of surgical oncology (01-01-2011)“…Background The peak incidence of glioblastoma multiforme (GBM) occurs in those aged 65 years and older. However, studies on this patient group remain limited…”
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Risk Factors for Preoperative Seizures and Loss of Seizure Control in Patients Undergoing Surgery for Metastatic Brain Tumors
Published in World neurosurgery (01-08-2017)“…Abstract Objective Metastatic brain tumors are the most common brain tumors in adults. Patients with metastatic brain tumors have poor prognoses with median…”
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Genomic Alterations in Molecularly Defined Oligodendrogliomas
Published in Neurosurgery (15-07-2024)“…Oligodendrogliomas are defined by IDH1/2 mutation and codeletion of chromosome arms 1p/19q. Although previous studies identified CIC, FUBP1, and TERTp as…”
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Establishment and Biological Characterization of a Panel of Glioblastoma Multiforme (GBM) and GBM Variant Oncosphere Cell Lines
Published in PloS one (30-03-2016)“…Human tumor cell lines form the basis of the majority of present day laboratory cancer research. These models are vital to studying the molecular biology of…”
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A comparative analysis of the Hospital Frailty Risk Score in predicting postoperative outcomes among intracranial tumor patients
Published in Journal of neurosurgery (01-08-2023)“…In recent years, frailty indices such as the 11- and 5-factor modified frailty indices (mFI-11 and mFI-5), American Society of Anesthesiologists (ASA) physical…”
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Surgical Resection for Primary Central Nervous System Lymphoma: A Systematic Review
Published in World neurosurgery (01-06-2019)“…Primary central nervous system lymphomas (PCNSLs) account for 1%–2% of primary central nervous system tumors. Until recently, treatment has centered on biopsy,…”
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Use of Gliadel (BCNU) Wafer in the Surgical Treatment of Malignant Glioma: A 10-Year Institutional Experience
Published in Annals of surgical oncology (01-10-2008)“…Background Gliadel (polifeprosan 20 with carmustine [BCNU] implant) is commonly used for local delivery of BCNU to high-grade gliomas after resection and is…”
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A Crowdsourced Consensus on Supratotal Resection Versus Gross Total Resection for Anatomically Distinct Primary Glioblastoma
Published in Neurosurgery (01-10-2021)“…Abstract BACKGROUND Gross total resection (GTR) of contrast-enhancing tumor is associated with increased survival in primary glioblastoma. Recently, there has…”
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Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme
Published in Journal of neurosurgery (01-03-2009)“…Gliadel (BCNU) wafer and concomitant temozolomide (TMZ) therapy, when used individually as adjuvant therapies, extend survival from that achieved by resection…”
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