Search Results - "Weiner, M W"

Alzheimer's Disease Neuroimaging Initiative (ADNI): Clinical characterization by PETERSEN, R. C, AISEN, P. S, TROJANOWSKI, J. Q, WEINER, M. W, BECKETT, L. A, DONOHUE, M. C, GAMST, A. C, HARVEY, D. J, JACK, C. R, JAGUST, W. J, SHAW, L. M, TOGA, A. W

“…Neuroimaging measures and chemical biomarkers may be important indices of clinical progression in normal aging and mild cognitive impairment (MCI) and need to…”
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Relationships between biomarkers in aging and dementia by JAGUST, W. J, LANDAU, S. M, MATHIS, C. A, SHAW, L. M, TROJANOWSKI, J. Q, KOEPPE, R. A, REIMAN, E. M, FOSTER, N. L, PETERSEN, R. C, WEINER, M. W, PRICE, J. C

“…PET imaging using [(18)F]fluorodeoxyglucose (FDG) and [(11)C]Pittsburgh compound B (PIB) have been proposed as biomarkers of Alzheimer disease (AD), as have…”
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MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers by Schuff, N., Woerner, N., Boreta, L., Kornfield, T., Shaw, L. M., Trojanowski, J. Q., Thompson, P. M., Jack, C. R., Weiner, M. W.

“…Hippocampal volume change over time, measured with MRI, has huge potential as a marker for Alzheimer's disease. The objectives of this study were: (i) to test…”
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MRI and CSF biomarkers in normal, MCI, and AD subjects Predicting future clinical change by VEMURI, P, WISTE, H. J, WEIGAND, S. D, SHAW, L. M, TROJANOWSKI, J. Q, WEINER, M. W, KNOPMAN, D. S, PETERSEN, R. C, JACK, C. R

“…To investigate the relationship between baseline MRI and CSF biomarkers and subsequent change in continuous measures of cognitive and functional abilities in…”
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Episodic memory loss is related to hippocampal-mediated  -amyloid deposition in elderly subjects by Mormino, E. C., Kluth, J. T., Madison, C. M., Rabinovici, G. D., Baker, S. L., Miller, B. L., Koeppe, R. A., Mathis, C. A., Weiner, M. W., Jagust, W. J.

“…Although β-amyloid (Aβ) plaques are a primary diagnostic criterion for Alzheimer's disease, this pathology is commonly observed in the brains of non-demented…”
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MRI and CSF biomarkers in normal, MCI, and AD subjects Diagnostic discrimination and cognitive correlations by VEMURI, P, WISTE, H. J, WEIGAND, S. D, SHAW, L. M, TROJANOWSKI, J. Q, WEINER, M. W, KNOPMAN, D. S, PETERSEN, R. C, JACK, C. R

“…To assess the correlations of both MRI and CSF biomarkers with clinical diagnosis and with cognitive performance in cognitively normal (CN) subjects and…”
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Comparing predictors of conversion and decline in mild cognitive impairment by LANDAU, S. M, HARVEY, D, WEINER, M. W, JAGUST, W. J, MADISON, C. M, REIMAN, E. M, FOSTER, N. L, AISEN, P. S, PETERSEN, R. C, SHAW, L. M, TROJANOWSKI, J. Q, JACK, C. R

“…A variety of measurements have been individually linked to decline in mild cognitive impairment (MCI), but the identification of optimal markers for predicting…”
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Diffusion tensor imaging of cingulum fibers in mild cognitive impairment and Alzheimer disease by ZHANG, Y, SCHUFF, N, CHUI, H, JAGUST, W. J, MILLER, B. L, WEINER, M. W, JAHNG, G.-H, BAYNE, W, MORI, S, SCHAD, L, MUELLER, S, DU, A.-T, KRAMER, J. H, YAFFE, K

“…Neuroimaging in mild cognitive impairment (MCI) and Alzheimer disease (AD) generally shows medial temporal lobe atrophy and diminished glucose metabolism and…”
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Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease by Furney, S J, Simmons, A, Breen, G, Pedroso, I, Lunnon, K, Proitsi, P, Hodges, A, Powell, J, Wahlund, L-O, Kloszewska, I, Mecocci, P, Soininen, H, Tsolaki, M, Vellas, B, Spenger, C, Lathrop, M, Shen, L, Kim, S, Saykin, A J, Weiner, M W, Lovestone, S

“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder with considerable evidence suggesting an initiation of disease in the entorhinal cortex…”
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Brain atrophy associated with baseline and longitudinal measures of cognition by Cardenas, V.A, Chao, L.L, Studholme, C, Yaffe, K, Miller, B.L, Madison, C, Buckley, S.T, Mungas, D, Schuff, N, Weiner, M.W

“…Abstract The overall goal was to identify patterns of brain atrophy associated with cognitive impairment and future cognitive decline in non-demented elders…”
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White matter lesions impair frontal lobe function regardless of their location by TULLBERG, M, FLETCHER, E, DECARLI, C, MUNGAS, D, REED, B. R, HARVEY, D. J, WEINER, M. W, CHUI, H. C, JAGUST, W. J

“…To analyze the effect of white matter lesions in different brain regions on regional cortical glucose metabolism, regional cortical atrophy, and cognitive…”
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Chronic divalproex sodium use and brain atrophy in Alzheimer disease by FLEISHER, A. S, TRURAN, D, TARIOT, P. N, MAI, J. T, LANGBAUM, J. B. S, AISEN, P. S, CUMMINGS, J. L, JACK, C. R, WEINER, M. W, THOMAS, R. G, SCHNEIDER, L. S

“…We evaluated the effect of the divalproex sodium formulation of valproic acid on brain volumes using MRI in people with mild to moderate Alzheimer disease (AD)…”
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Distinct clinical and metabolic deficits in PCA and AD are not related to amyloid distribution by ROSENBLOOM, M. H, ALKALAY, A, MORMINO, E. C, ROSEN, H. J, GORNO-TEMPINI, M. L, WEINER, M. W, MILLER, B. L, JAGUST, W. J, RABINOVICI, G. D, AGARWAL, N, BAKER, S. L, O'NEIL, J. P, JANABI, M, YEN, I. V, GROWDON, M, JANG, J, MADISON, C

“…Patients with posterior cortical atrophy (PCA) often have Alzheimer disease (AD) at autopsy, yet are cognitively and anatomically distinct from patients with…”
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Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease by Du, A T, Schuff, N, Amend, D, Laakso, M P, Hsu, Y Y, Jagust, W J, Yaffe, K, Kramer, J H, Reed, B, Norman, D, Chui, H C, Weiner, M W

“…OBJECTIVES To explore volume changes of the entorhinal cortex (ERC) and hippocampus in mild cognitive impairment (MCI) and Alzheimer's disease (AD) compared…”
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Fear conditioning in frontotemporal lobar degeneration and Alzheimer's disease by Hoefer, M., Allison, S. C., Schauer, G. F., Neuhaus, J. M., Hall, J., Dang, J. N., Weiner, M. W., Miller, B. L., Rosen, H. J.

“…Emotional blunting and abnormal processing of rewards and punishments represent early features of frontotemporal lobar degeneration (FTLD). Better…”
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Hippocampal atrophy rates and CSF biomarkers in elderly APOE2 normal subjects by CHIANG, G. C, INSEL, P. S, TOSUN, D, SCHUFF, N, TRURAN-SACREY, D, RAPTENTSETSANG, S. T, JACK, C. R, AISEN, P. S, PETERSEN, R. C, WEINER, M. W

“…To determine whether elderly normal APOE E2 (APOE2) carriers exhibit slower rates of hippocampal atrophy and memory decline compared to APOE3/3 carriers. We…”
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MRI predictors of cognition in subcortical ischemic vascular disease and Alzheimer's disease by MUNGAS, D, JAGUST, W. J, REED, B. R, KRAMER, J. H, WEINER, M. W, SCHUFF, N, NORMAN, D, MACK, W. J, WILLIS, L, CHUI, H. C

“…Causes of cognitive impairment in subcortical ischemic vascular disease (SIVD) are less well understood than in AD, but have been thought to result from direct…”
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White Matter Alterations in Cognitively Normal apoE ε2 Carriers: Insight into Alzheimer Resistance? by CHIANG, G. C, ZHAN, W, SCHUFF, N, WEINER, M. W

“…The basis for decreased vulnerability to AD among apoE ε2 carriers is unknown. The purpose of this study was to use diffusion tensor imaging to detect possible…”
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Higher atrophy rate of entorhinal cortex than hippocampus in AD by DU, A. T, SCHUFF, N, CHUI, H. C, WEINER, M. W, KRAMER, J. H, GANZER, S, ZHU, X. P, JAGUST, W. J, MILLER, B. L, REED, B. R, MUNGAS, D, YAFFE, K

“…To determine if atrophy rates were higher for entorhinal cortex (ERC) than for hippocampus in Alzheimer disease (AD), to determine the relationship between…”
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Hippocampal and cortical atrophy predict dementia in subcortical ischemic vascular disease by FEIN, G, DI SCLAFANI, V, GREENFIELD, T, CHUI, H, TANABE, J, CARDENAS, V, WEINER, M. W, JAGUST, W. J, REED, B. R, NORMAN, D, SCHUFF, N, KUSDRA, L

“…The cause of dementia in subcortical ischemic vascular disease (SIVD) is controversial. To determine whether cognitive impairment in SIVD 1) correlates with…”
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