Search Results - "Weiner, Joshua"

Deterministic Squeezed States with Collective Measurements and Feedback by Cox, Kevin C, Greve, Graham P, Weiner, Joshua M, Thompson, James K

“…We demonstrate the creation of entangled, spin-squeezed states using a collective, or joint, measurement and real-time feedback. The pseudospin state of an…”
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Combinatorial homophilic interaction between γ-protocadherin multimers greatly expands the molecular diversity of cell adhesion by Schreiner, Dietmar, Weiner, Joshua A

“…The specificity of interactions between neurons is believed to be mediated by diverse cell adhesion molecules, including members of the cadherin superfamily…”
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Regulation of neural circuit formation by protocadherins by Peek, Stacey L., Mah, Kar Men, Weiner, Joshua A.

“…The protocadherins (Pcdhs), which make up the most diverse group within the cadherin superfamily, were first discovered in the early 1990s. Data implicating…”
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CRISPR/Cas9 interrogation of the mouse Pcdhg gene cluster reveals a crucial isoform-specific role for Pcdhgc4 by Garrett, Andrew M, Bosch, Peter J, Steffen, David M, Fuller, Leah C, Marcucci, Charles G, Koch, Alexis A, Bais, Preeti, Weiner, Joshua A, Burgess, Robert W

“…The mammalian Pcdhg gene cluster encodes a family of 22 cell adhesion molecules, the gamma-Protocadherins (γ-Pcdhs), critical for neuronal survival and neural…”
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Safety, pharmacokinetics, and immunogenicity of the combination of the broadly neutralizing anti-HIV-1 antibodies 3BNC117 and 10-1074 in healthy adults: A randomized, phase 1 study by Cohen, Yehuda Z, Butler, Allison L, Millard, Katrina, Witmer-Pack, Maggi, Levin, Rebeka, Unson-O'Brien, Cecilia, Patel, Roshni, Shimeliovich, Irina, Lorenzi, Julio C C, Horowitz, Jill, Walsh, Stephen R, Lin, Shu, Weiner, Joshua A, Tse, Anna, Sato, Alicia, Bennett, Chelsey, Mayer, Bryan, Seaton, Kelly E, Yates, Nicole L, Baden, Lindsey R, deCamp, Allan C, Ackerman, Margaret E, Seaman, Michael S, Tomaras, Georgia D, Nussenzweig, Michel C, Caskey, Marina

“…Additional forms of pre-exposure prophylaxis are needed to prevent HIV-1 infection. 3BNC117 and 10-1074 are broadly neutralizing anti-HIV-1 antibodies that…”
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Homophilic Protocadherin Cell-Cell Interactions Promote Dendrite Complexity by Molumby, Michael J., Keeler, Austin B., Weiner, Joshua A.

“…Growth of a properly complex dendrite arbor is a key step in neuronal differentiation and a prerequisite for neural circuit formation. Diverse cell surface…”
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Regulation of Wnt signaling by protocadherins by Mah, Kar Men, Weiner, Joshua A.

“…The ∼70 protocadherins comprise the largest group within the cadherin superfamily. Their diversity, the complexity of the mechanisms through which their genes…”
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γ-Protocadherins Control Cortical Dendrite Arborization by Regulating the Activity of a FAK/PKC/MARCKS Signaling Pathway by Garrett, Andrew M., Schreiner, Dietmar, Lobas, Mark A., Weiner, Joshua A.

“…The 22 γ-protocadherins (γ-Pcdhs) potentially specify thousands of distinct homophilic adhesive interactions in the brain. Neonatal lethality of mice lacking…”
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A steady-state superradiant laser with less than one intracavity photon by Bohnet, Justin G., Chen, Zilong, Weiner, Joshua M., Meiser, Dominic, Holland, Murray J., Thompson, James K.

“…A superradiant laser with less than one intracavity photon is shown to synchronize its lasing medium spontaneously and simultaneously isolate it from the…”
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Cardiac Xenotransplantation: Clinical Impact of Science and Discovery by Garry, Daniel J., Weiner, Joshua I., Greising, Sarah M., Garry, Mary G., Sachs, David H.

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Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge by Om, Kier, Paquin-Proulx, Dominic, Montero, Maria, Peachman, Kristina, Shen, Xiaoying, Wieczorek, Lindsay, Beck, Zoltan, Weiner, Joshua A, Kim, Dohoon, Li, Yifan, Mdluli, Thembi, Shubin, Zhanna, Bryant, Christopher, Sharma, Vishakha, Tokarev, Andrey, Dawson, Peter, White, Yohann, Appelbe, Oliver, Klatt, Nichole R, Tovanabutra, Sodsai, Estes, Jacob D, Matyas, Gary R, Ferrari, Guido, Alving, Carl R, Tomaras, Georgia D, Ackerman, Margaret E, Michael, Nelson L, Robb, Merlin L, Polonis, Victoria, Rolland, Morgane, Eller, Michael A, Rao, Mangala, Bolton, Diane L

“…To augment HIV-1 pox-protein vaccine immunogenicity using a next generation adjuvant, a prime-boost strategy of recombinant modified vaccinia virus Ankara and…”
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Protocadherins and other atypical cadherins by Weiner, Joshua A.

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Dendritic Cells Display Subset and Tissue-Specific Maturation Dynamics over Human Life by Granot, Tomer, Senda, Takashi, Carpenter, Dustin J., Matsuoka, Nobuhide, Weiner, Joshua, Gordon, Claire L., Miron, Michelle, Kumar, Brahma V., Griesemer, Adam, Ho, Siu-Hong, Lerner, Harvey, Thome, Joseph J.C., Connors, Thomas, Reizis, Boris, Farber, Donna L.

“…Maturation and migration to lymph nodes (LNs) constitutes a central paradigm in conventional dendritic cell (cDC) biology but remains poorly defined in humans…”
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Distinct Features and Functions of Systemic and Mucosal Humoral Immunity Among SARS-CoV-2 Convalescent Individuals by Butler, Savannah E, Crowley, Andrew R, Natarajan, Harini, Xu, Shiwei, Weiner, Joshua A, Bobak, Carly A, Mattox, Daniel E, Lee, Jiwon, Wieland-Alter, Wendy, Connor, Ruth I, Wright, Peter F, Ackerman, Margaret E

“…Understanding humoral immune responses to SARS-CoV-2 infection will play a critical role in the development of vaccines and antibody-based interventions. We…”
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Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV by Ackerman, Margaret E., Das, Jishnu, Pittala, Srivamshi, Broge, Thomas, Linde, Caitlyn, Suscovich, Todd J., Brown, Eric P., Bradley, Todd, Natarajan, Harini, Lin, Shu, Sassic, Jessica K., O’Keefe, Sean, Mehta, Nickita, Goodman, Derrick, Sips, Magdalena, Weiner, Joshua A., Tomaras, Georgia D., Haynes, Barton F., Lauffenburger, Douglas A., Bailey-Kellogg, Chris, Roederer, Mario, Alter, Galit

“…Antibodies are the primary correlate of protection for most licensed vaccines; however, their mechanisms of protection may vary, ranging from physical blockade…”
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Mining for humoral correlates of HIV control and latent reservoir size by Das, Jishnu, Devadhasan, Anush, Linde, Caitlyn, Broge, Tom, Sassic, Jessica, Mangano, Max, O'Keefe, Sean, Suscovich, Todd, Streeck, Hendrik, Irrinki, Alivelu, Pohlmeyer, Chris, Min-Oo, Gundula, Lin, Shu, Weiner, Joshua A, Cihlar, Thomas, Ackerman, Margaret E, Julg, Boris, Deeks, Steven, Lauffenburger, Douglas A, Alter, Galit

“…While antiretroviral therapy (ART) has effectively revolutionized HIV care, the virus is never fully eliminated. Instead, immune dysfunction, driven by…”
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Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women by Martinez, David R., Fong, Youyi, Li, Shuk Hang, Yang, Fang, Jennewein, Madeleine F., Weiner, Joshua A., Harrell, Erin A., Mangold, Jesse F., Goswami, Ria, Seage, George R., Alter, Galit, Ackerman, Margaret E., Peng, Xinxia, Fouda, Genevieve G., Permar, Sallie R.

“…The placental transfer of maternal IgG is critical for infant protection against infectious pathogens. However, factors that modulate the placental transfer of…”
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Longitudinal Systemic and Mucosal Immune Responses to SARS-CoV-2 Infection by Wright, Peter F, Prevost-Reilly, Alejandra C, Natarajan, Harini, Brickley, Elizabeth B, Connor, Ruth I, Wieland-Alter, Wendy F, Miele, Anna S, Weiner, Joshua A, Nerenz, Robert D, Ackerman, Margaret E

“…A longitudinal study determined the breadth, kinetics, and correlations of systemic and mucosal antibody responses to SARS-CoV-2 infection. Twenty-six…”
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Akirin proteins in development and disease: critical roles and mechanisms of action by Bosch, Peter J., Peek, Stacey L., Smolikove, Sarit, Weiner, Joshua A.

“…The Akirin genes, which encode small, nuclear proteins, were first characterized in 2008 in Drosophila and rodents. Early studies demonstrated important roles…”
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Protein Kinase C Phosphorylation of a γ-Protocadherin C-terminal Lipid Binding Domain Regulates Focal Adhesion Kinase Inhibition and Dendrite Arborization by Keeler, Austin B., Schreiner, Dietmar, Weiner, Joshua A.

“…The γ-protocadherins (γ-Pcdhs) are a family of 22 adhesion molecules with multiple critical developmental functions, including the proper formation of…”
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