Search Results - "Weiner, DB"

Comparison of cellular and humoral immune responses induced by primary, consensus or mosaic HIV-1 Env DNA vaccines by Yan, J, Pankhong, P, Khan, AS, Sardesai, NY, Weiner, DB

“…Doc number: P333…”
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Robust antibody and cellular responses with an improved DNA vaccine alone by Hutnick, N, Myles, DJ, Muthumani, K, Morrow, M, Yan, J, Khan, AS, Sardasai, NY, Weiner, DB

“…Doc number: P15…”
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Minimally invasive and surface electroporation delivery of DNA vaccines for the induction of robust humoral immune responses against HIV antigens by Sardesai, NY, Khan, AS, McCoy, J, Lin, F, Mendoza, JM, Yang, M, Yan, J, Hutnick, N, Muthumani, K, Weiner, DB, Broderick, KE

“…Doc number: O9…”
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E-DNA IM or ID delivery prime enhances antibody and T cell responses following recombinant gp120 env boost by Hutnick, NA, Karuppiah, M, Pollara, J, Yan, J, Myles, DJ, Broderick, K, Morrow, M, Sardasai, N, Montefiori, D, Barnett, S, Ferrari, G, Weiner, DB

“…Doc number: P364…”
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Improved systemic and mucosal antibody responses with a CCR10 ligand adjuvant by Hutnick, N, Myles, DJ, Ginsberg, A, Khan, AS, Yan, J, Moldoveanu, Z, Mestecky, J, Marx, PA, Kutzler, M, Weiner, DB

“…Doc number: P203…”
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Potent cellular immune responses after therapeutic immunization of HIV-positive patients with the PENNVAX®-B DNA vaccine in a Phase I Trial by Tebas, P, Ramirez, L, Morrow, MP, Yan, J, Shah, D, Lee, J, Weiner, DB, Boyer, J, Bagarazzi, M, Sardesai, NY

“…Doc number: P276…”
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DNA vaccines expressing conserved elements provide potent and broad immune responses by Pavlakis, GN, Kulkarni, V, Valentin, A, Rosati, M, Sardesai, NY, Mothe, B, Brander, C, LeGall, S, Weiner, DB, Rolland, M, Mullins, JI, Felber, BK

“…Doc number: O67…”
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OA05-02. Analysis of DNA compared to Ad5 vaccination, as single and mixed modalities, demonstrates robust induction of cellular immune responses in macaques by Hirao, LA, Wu, L, Satishchandran, A, Khan, AS, Finnefrock, A, Casimiro, D, Shiver, J, Betts, MR, Sardesai, NY, Weiner, DB

“…Meeting abstracts - A single PDF containing all abstracts in this Supplement is available at…”
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P19-46. Co-delivery of mucosal chemokine plasmids in a systemically delivered DNA vaccine elicits systemic and mucosal immune responses in mice and macaques by Kraynyak, KA, Kutzler, MA, Pahar, B, Sylvester, A, Yan, J, Carnathan, D, Khan, AS, Sardesai, N, Moldoveanu, Z, Mestecky, J, Betts, MR, Marx, P, Weiner, DB

“…From: AIDS Vaccine 2009 Paris, France 19-22 October 2009 Author details 1-Department of Pathology and Laboratory Medicine, University of Pennsylvania,…”
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P19-49. Modulation of vaccine induced responses through CTLA-4 and 41BB enhances protection in macaques following SIVmac251 challenge by Hirao, LA, Hokey, DA, Weber, J, Yan, J, Boyer, JD, Dai, A, Anderson, H, Lewis, M, Jure-Kunkel, MN, Weiner, DB

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P03-11. DNA vaccination with IL-12 lowers viral replication following SIVmac251 challenge by Hirao, LA, Wu, L, Khan, AS, Dai, A, Karl, J, Lank, S, Wiseman, R, O'Connor, D, Watkins, D, Miller, N, Betts, MR, Sardesai, NY, Boyer, JD, Weiner, DB

“…Results Viral loads were followed out 35 weeks post-infection and area under the curve analysis revealed that the DNA and the DNA+12 group had a significant…”
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Novel strategy for generation of mucosal immune responses against HIV-1 following systemic vaccination by Kutzler, Michele A, Schoenly, Kimberly A, Muthumani, Karuppiah, Parkinson, Rose M, Maquire, Henry, Ugen, Kenneth, Weiner, D B

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Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors by Lieberman, Judy, Song, Erwei, Zhu, Pengcheng, Lee, Sang-Kyung, Chowdhury, Dipanjan, Kussman, Steven, Dykxhoorn, Derek M, Feng, Yi, Palliser, Deborah, Weiner, David B, Shankar, Premlata, Marasco, Wayne A

“…Delivery of small interfering RNAs (siRNAs) into cells is a key obstacle to their therapeutic application. We designed a protamine-antibody fusion protein to…”
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Developing DNA vaccines that call to dendritic cells by Kutzler, Michele A., Weiner, David B.

“…DNA vaccination is a novel immunization strategy that has great potential for the development of vaccines and immune therapeutics. This strategy has been…”
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Molecular adjuvant HMGB1 enhances anti-influenza immunity during DNA vaccination by Fagone, P, Shedlock, D J, Bao, H, Kawalekar, O U, Yan, J, Gupta, D, Morrow, M P, Patel, A, Kobinger, G P, Muthumani, K, Weiner, D B

“…DNA-based vaccines, while highly immunogenic in mice, generate significantly weaker responses in primates. Therefore, current efforts are aimed at increasing…”
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Enhancement of human immunodeficiency virus type 1-DNA vaccine potency through incorporation of T-helper 1 molecular adjuvants by Calarota, Sandra A., Weiner, David B.

“…It is clear that the development of a safe and effective vaccine for human immunodeficiency virus type 1 (HIV‐1) remains a crucial goal for controlling the…”
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Coimmunization with an Optimized IL-15 Plasmid Results in Enhanced Function and Longevity of CD8 T Cells That Are Partially Independent of CD4 T Cell Help by Kutzler, Michele A, Robinson, Tara M, Chattergoon, Michael A, Choo, Daniel K, Choo, Andrew Y, Choe, Philip Y, Ramanathan, Mathura P, Parkinson, Rose, Kudchodkar, Sagar, Tamura, Yutaka, Sidhu, Maninder, Roopchand, Vidia, Kim, J. Joseph, Pavlakis, George N, Felber, Barbara K, Waldmann, Thomas A, Boyer, Jean D, Weiner, David B

“…DNA vaccines are a promising technology for the induction of Ag-specific immune responses, and much recent attention has gone into improving their immune…”
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Plasmids encoding the mucosal chemokines CCL27 and CCL28 are effective adjuvants in eliciting antigen-specific immunity in vivo by Kutzler, M A, Kraynyak, K A, Nagle, S J, Parkinson, R M, Zharikova, D, Chattergoon, M, Maguire, H, Muthumani, K, Ugen, K, Weiner, D B

“…A hurdle facing DNA vaccine development is the ability to generate strong immune responses systemically and at local immune sites. We report a novel…”
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Introduction by Weiner, DB

“…[...]improving the immune potency and deliverability of DNA vaccines has grown to be a central issue in this emerging field. [...]special thanks go to Caroline…”
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DNA Vaccines against Human Immunodeficiency Virus Type 1 in the Past Decade by GIRI, Malavika, UGEN, Kenneth E, WEINER, David B

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