Search Results - "Weiner, Amber"

High-Quality Genome Assemblies Reveal Long Non-coding RNAs Expressed in Ant Brains by Shields, Emily J., Sheng, Lihong, Weiner, Amber K., Garcia, Benjamin A., Bonasio, Roberto

“…Ants are an emerging model system for neuroepigenetics, as embryos with virtually identical genomes develop into different adult castes that display diverse…”
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Surface and Global Proteome Analyses Identify ENPP1 and Other Surface Proteins as Actionable Immunotherapeutic Targets in Ewing Sarcoma by Mooney, Brian, Negri, Gian Luca, Shyp, Taras, Delaidelli, Alberto, Zhang, Hai-Feng, Spencer Miko, Sandra E, Weiner, Amber K, Radaoui, Alexander B, Shraim, Rawan, Lizardo, Michael M, Hughes, Christopher S, Li, Amy, El-Naggar, Amal M, Rouleau, Melanie, Li, Wei, Dimitrov, Dimiter S, Kurmasheva, Raushan T, Houghton, Peter J, Diskin, Sharon J, Maris, John M, Morin, Gregg B, Sorensen, Poul H

“…Ewing sarcoma is the second most common bone sarcoma in children, with 1 case per 1.5 million in the United States. Although the survival rate of patients…”
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Graphical Interpretation and Analysis of Proteins and their Ontologies (GiaPronto): A One-Click Graph Visualization Software for Proteomics Data Sets by Weiner, Amber K., Sidoli, Simone, Diskin, Sharon J., Garcia, Benjamin A.

“…Here we present a free interactive web tool to process and visualize proteomics data sets with a single click. GiaPronto can process all proteomics…”
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Advancing childhood cancer research through young investigator and advocate collaboration by Weiner, Amber K, Palmer, Antonia, Moll, Melanie Frost, Lindberg, Gavin, Reidy, Kevin, Diskin, Sharon J, Mackall, Crystal L, Maris, John M, Sullivan, Patrick J

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Subtelomeric CTCF and cohesin binding site organization using improved subtelomere assemblies and a novel annotation pipeline by Stong, Nicholas, Deng, Zhong, Gupta, Ravi, Hu, Sufen, Paul, Shiela, Weiner, Amber K, Eichler, Evan E, Graves, Tina, Fronick, Catrina C, Courtney, Laura, Wilson, Richard K, Lieberman, Paul M, Davuluri, Ramana V, Riethman, Harold

“…Mapping genome-wide data to human subtelomeres has been problematic due to the incomplete assembly and challenges of low-copy repetitive DNA elements. Here, we…”
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Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs by Yarmarkovich, Mark, Marshall, Quinlen F, Warrington, John M, Premaratne, Rasika, Farrel, Alvin, Groff, David, Li, Wei, di Marco, Moreno, Runbeck, Erin, Truong, Hau, Toor, Jugmohit S, Tripathi, Sarvind, Nguyen, Son, Shen, Helena, Noel, Tiffany, Church, Nicole L, Weiner, Amber, Kendsersky, Nathan, Martinez, Dan, Weisberg, Rebecca, Christie, Molly, Eisenlohr, Laurence, Bosse, Kristopher R, Dimitrov, Dimiter S, Stevanovic, Stefan, Sgourakis, Nikolaos G, Kiefel, Ben R, Maris, John M

“…The majority of oncogenic drivers are intracellular proteins, thus constraining their immunotherapeutic targeting to mutated peptides (neoantigens) presented…”
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Abstract 2633: Advancing childhood cancer research through young investigator and advocate collaboration by Weiner, Amber K., Lindberg, Gavin, Moll, Melanie, Palmer, Antonia, Reidy, Kevin, Diskin, Sharon J., Mackall, Crystal L., Maris, John M., Sullivan, Patrick J.

“…Abstract Background: Cancer advocates and researchers share the same goal of driving science forward to create new therapies to cure more patients. The power…”
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Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of linc-ADAL in adipocyte metabolism by Zhang, Xuan, Xue, Chenyi, Lin, Jennie, Ferguson, Jane F, Weiner, Amber, Liu, Wen, Han, Yumiao, Hinkle, Christine, Li, Wenjun, Jiang, Hongfeng, Gosai, Sager, Hachet, Melanie, Garcia, Benjamin A, Gregory, Brian D, Soccio, Raymond E, Hogenesch, John B, Seale, Patrick, Li, Mingyao, Reilly, Muredach P

“…Long intergenic noncoding RNAs (lincRNAs) have emerged as important modulators of cellular functions. Most lincRNAs are not conserved among mammals, raising…”
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Targeting of intracellular oncoproteins with peptide-centric CARs by Yarmarkovich, Mark, Marshall, Quinlen F., Warrington, John M., Premaratne, Rasika, Farrel, Alvin, Groff, David, Li, Wei, di Marco, Moreno, Runbeck, Erin, Truong, Hau, Toor, Jugmohit S., Tripathi, Sarvind, Nguyen, Son, Shen, Helena, Noel, Tiffany, Church, Nicole L., Weiner, Amber, Kendsersky, Nathan, Martinez, Dan, Weisberg, Rebecca, Christie, Molly, Eisenlohr, Laurence, Bosse, Kristopher R., Dimitrov, Dimiter S., Stevanovic, Stefan, Sgourakis, Nikolaos G., Kiefel, Ben R., Maris, John M.

“…The majority of oncogenic drivers are intracellular proteins, constraining their immunotherapeutic targeting to mutated peptides (neoantigens) presented by…”
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Retraction Note: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs by Yarmarkovich, Mark, Marshall, Quinlen F., Warrington, John M., Premaratne, Rasika, Farrel, Alvin, Groff, David, Li, Wei, di Marco, Moreno, Runbeck, Erin, Truong, Hau, Toor, Jugmohit S., Tripathi, Sarvind, Nguyen, Son, Shen, Helena, Noel, Tiffany, Church, Nicole L., Weiner, Amber, Kendsersky, Nathan, Martinez, Dan, Weisberg, Rebecca, Christie, Molly, Eisenlohr, Laurence, Bosse, Kristopher R., Dimitrov, Dimiter S., Stevanovic, Stefan, Sgourakis, Nikolaos G., Kiefel, Ben R., Maris, John M.

“…Following the publication of our manuscript, a new high-resolution structure of the HLA-A·24:02/PHOX2B peptide/10LH scFv complex by X-ray crystallography…”
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RETRACTED ARTICLE: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs by Yarmarkovich, Mark, Marshall, Quinlen F., Warrington, John M., Premaratne, Rasika, Farrel, Alvin, Groff, David, Li, Wei, di Marco, Moreno, Runbeck, Erin, Truong, Hau, Toor, Jugmohit S., Tripathi, Sarvind, Nguyen, Son, Shen, Helena, Noel, Tiffany, Church, Nicole L., Weiner, Amber, Kendsersky, Nathan, Martinez, Dan, Weisberg, Rebecca, Christie, Molly, Eisenlohr, Laurence, Bosse, Kristopher R., Dimitrov, Dimiter S., Stevanovic, Stefan, Sgourakis, Nikolaos G., Kiefel, Ben R., Maris, John M.

“…The majority of oncogenic drivers are intracellular proteins, thus constraining their immunotherapeutic targeting to mutated peptides (neoantigens) presented…”
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Abstract 684: Integrative proteomics and transcriptomics to define the cell surface landscape of neuroblastoma by Weiner, Amber K., Sidoli, Simone, Glisovic-Aplenc, Tina, Maris, John M., Garcia, Benjamin A., Diskin, Sharon J.

“…Abstract BACKGROUND. Neuroblastoma (NB) is an embryonal tumor of the sympathetic nervous system that accounts for 12% of childhood cancer deaths. Despite…”
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Advancing Immunotherapy Through Proteogenomics: Identification and Validation of DLK1 as a Target in Neuroblastoma by Weiner, Amber Kathryn

“…Neuroblastoma is an embryonal tumor of the sympathetic nervous system that accounts for 12% of childhood cancer deaths. Despite multimodal therapy, survival…”
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Abstract 3650: Integrative mass spectrometry and RNA-sequencing identifies DLK1 as a candidate immunotherapeutic target in neuroblastoma by Weiner, Amber K., Radaoui, Alexander B., Kendsersky, Nathan M., Harenza-Rokita, Jo Lynne, Sidoli, Simone, Conkrite, Karina L., Vaksman, Zalman, Rathi, Komal, Raman, Pichai, Martinez, Daniel, Bhatti, Tricia, Tsang, Matthew, Pawel, Bruce, Garcia, Benjamin A., Maris, John M., Diskin, Sharon J.

“…Abstract BACKGROUND. Neuroblastoma (NB) is an embryonal tumor of the sympathetic nervous system that accounts for 12% of childhood cancer deaths. Despite…”
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Abstract 6573: Targeting DLK1, a Notch ligand, with an antibody-drug conjugate in adrenocortical carcinoma by Sun, Nai-Yun, Kumar, Suresh, Weiner, Amber, Kim, Yoo Sun, Mendoza, Arnulfo, Nguyen, Rosa, Okada, Reona, Pommier, Yves, Martinez, Dan, Pogoriler, Jennifer, Diskin, Sharon, Maris, John, Del Rivero, Jaydira, Roper, Nitin

“…Abstract Adrenocortical carcinoma (ACC) is an aggressive and rare endocrine malignancy with poor prognosis. First-line therapy (adrenolytic agent mitotane in…”
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Abstract LB-B04: A multi-omic surfaceome study identifies DLK1 as an epigenetically regulated protein and immunotherapeutic target in neuroblastoma by Weiner, Amber K., Radaoui, Alexander B., Tsang, Matthew, Martinez, Dan, Sidoli, Simone, Conkrite, Karina L., Delaidelli, Alberto, Rokita, Jo Lynne, Lane, Maria V., Vaksman, Zalman, Rathi, Komal S., Raman, Pichai, Pogoriler, Jennifer, Bhatti, Tricia, Pawel, Bruce, Teicher, Beverly, Erickson, Stephen W., Sorensen, Poul, Mosse, Yael P., Krytska, Kateryna, Zammarchi, Francesca, Berkel, Patrick H. van, Smith, Malcolm A., Garcia, Benjamin A., Maris, John M., Diskin, Sharon J.

“…Abstract Background: Neuroblastoma (NB) is an embryonal tumor of the sympathetic nervous system that accounts for 12% of childhood cancer deaths. While the…”
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Abstract 2012: A humanized anaplastic lymphoma kinase (ALK)-directed antibody-drug conjugate (ADC) demonstrates potent cytotoxicity in neuroblastoma (NBL) and fusion positive rhabdomyosarcoma (FP RMS) by Guerra, Alberto D., Kennedy, Annie, Adams, Cynthia, Shraim, Rawan, Weiner, Amber K., Chen, Chuan, Krytska, Kateryna, Larmour, Colleen, Matkar, Smita, Dimitrov, Dimiter, Jelev, Dontcho V., Mossé, Yael P.

“…Abstract Introduction: ALK is a lineage restricted oncoprotein expressed on the cell surface of NBL as wild-type (WT), mutated, or amplified, and recently…”
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Abstract 1090: GPC2 directed CAR T cells are efficacious against fusion-positive and fusion-negative rhabdomyosarcomas by Shraim, Rawan, Schuerch, Patrick M., Giudice, Anna Maria, Conkrite, Karina L., Weiner, Amber K., Radaoui, Alexander B., Mooney, Brian, Kurmasheva, Raushan T., Houghton, Peter J., Morin, Gregg B., Mosse, Yael B., Sorensen, Poul H., Garcia, Benjamin A., Sacan, Ahmet, Maris, John M., Bosse, Kristopher R., Diskin, Sharon J.

“…Abstract Background: Rhabdomyosarcoma (RMS) is an aggressive pediatric solid tumor with poor survival and new targeted therapies are needed. Aims: Using an…”
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Abstract A009: Proteogenomic prioritization of immunotherapeutic targets in rhabdomyosarcoma nominate MEGF10 for preclinical development by Shraim, Rawan, Weiner, Amber K., Conkrite, Karina L., Radaoui, Alexander B., Maris, John M., Mosse, Yael P., Diskin, Sharon J., Sacan, Ahmet, Garcia, Benjamin A., Houghton, Peter J., Kurmasheva, Raushan T., Sorensen, Poul, Morin, Gregg B., Mooney, Brian

“…Abstract Background: Rhabdomyosarcoma (RMS) has a high unmet need in terms of precision therapy development as there are currently no approved immunotherapies…”
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Abstract 4515: PIONEER: harnessing multi-omics data to enhance immunotherapeutic target discovery and development by Weiner, Amber K., Murali, Hemma, Shraim, Rawan, Conkrite, Karina L., Radaoui, Alexander B., Martinez, Daniel, Mooney, Brian, Spencer Miko, Sandra E., Negri, Gian, Delaidelli, Alberto, de Jong, Caitlyn, Zhu, Yuankun, Heath, Allison P., Pogoriler, Jennifer, Mosse, Yael P., Taylor, Deanne M., Sorensen, Poul H., Morin, Gregg B., Garcia, Benjamin A., Maris, John M., Diskin, Sharon J.

“…Abstract Introduction: Immunotherapeutic strategies have produced remarkable results in some malignancies. However, optimal cell surface targets in many…”
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