Search Results - "Weiner, Alan"

An Integrated Developmental Approach to Personality Disorders in Adolescence: Expanding Kernberg's Object Relations Theory by Normandin, Lina, Alan Weiner, Karin Ensink

“…This article is a tribute to Dr. Otto F. Kernberg and his contribution to the theoretical understanding of personality pathology in adolescence. In his object…”
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TFOS DEWS II iatrogenic report by Gomes, José Alvaro P., Azar, Dimitri T., Baudouin, Christophe, Efron, Nathan, Hirayama, Masatoshi, Horwath-Winter, Jutta, Kim, Terry, Mehta, Jodhbir S., Messmer, Elisabeth M., Pepose, Jay S., Sangwan, Virender S., Weiner, Alan L., Wilson, Steven E., Wolffsohn, James S.

“…Dry eye can be caused by a variety of iatrogenic interventions. The increasing number of patients looking for eye care or cosmetic procedures involving the…”
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Psychotherapy for Borderline Personality Disorder in Adolescents by Weiner, Alan S., PhD, Ensink, Karin, PhD, Normandin, Lina, PhD

“…Research on borderline personality disorder (BPD) in adolescence has helped to clarify the characteristics of BPD in young people. The considerable emotional…”
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Drug and gene delivery to the back of the eye: from bench to bedside by Rowe-Rendleman, Cheryl L, Durazo, Shelley A, Kompella, Uday B, Rittenhouse, Kay D, Di Polo, Adriana, Weiner, Alan L, Grossniklaus, Hans E, Naash, Muna I, Lewin, Alfred S, Horsager, Alan, Edelhauser, Henry F

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Cockayne Syndrome Group B Protein (CSB) Plays a General Role in Chromatin Maintenance and Remodeling by Newman, John C., Bailey, Arnold D., Weiner, Alan M.

“…Cockayne syndrome (CS) is an inherited neurodevelopmental disorder with progeroid features. Although the genes responsible for CS have been implicated in a…”
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Tethering of the conserved piggyBac transposase fusion protein CSB-PGBD3 to chromosomal AP-1 proteins regulates expression of nearby genes in humans by Gray, Lucas T, Fong, Kimberly K, Pavelitz, Thomas, Weiner, Alan M

“…The CSB-PGBD3 fusion protein arose more than 43 million years ago when a 2.5-kb piggyBac 3 (PGBD3) transposon inserted into intron 5 of the Cockayne syndrome…”
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An abundant evolutionarily conserved CSB-PiggyBac fusion protein expressed in Cockayne syndrome by Newman, John C, Bailey, Arnold D, Fan, Hua-Ying, Pavelitz, Thomas, Weiner, Alan M

“…Cockayne syndrome (CS) is a devastating progeria most often caused by mutations in the CSB gene encoding a SWI/SNF family chromatin remodeling protein…”
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What role (if any) does the highly conserved CSB-PGBD3 fusion protein play in Cockayne syndrome? by Weiner, Alan M., Gray, Lucas T.

“…► Cockayne syndrome (CS) is a devastating progeria usually caused by CSB mutations. ► A piggyBac transposon inserted into the primate CSB gene over 43 million…”
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SINEs and LINEs: the art of biting the hand that feeds you by Weiner, Alan M

“…SINEs and LINEs are short and long interspersed retrotransposable elements, respectively, that invade new genomic sites using RNA intermediates. SINEs and…”
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tRNA Maturation: RNA Polymerization without a Nucleic Acid Template by Weiner, Alan M.

“…The CCA-adding enzyme, which builds and repairs the 3′ terminal CCA sequence of tRNA, is the only RNA polymerase that can synthesize a defined nucleotide…”
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The conserved Cockayne syndrome B-piggyBac fusion protein (CSB-PGBD3) affects DNA repair and induces both interferon-like and innate antiviral responses in CSB-null cells by Bailey, Arnold D., Gray, Lucas T., Pavelitz, Thomas, Newman, John C., Horibata, Katsuyoshi, Tanaka, Kiyoji, Weiner, Alan M.

“…► Cockayne syndrome is a devasting childhood progeria most often caused by defects in the CSB gene. ► The CSB gene encodes a repair and chromatin remodeling…”
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Advancements in ocular drug delivery by Weiner, Alan L, Gilger, Brian C

“…This review covers both noninvasive and invasive ophthalmic drug delivery systems that can have application to therapy of veterinary ophthalmic diseases…”
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E Pluribus Unum: 3′ End Formation of Polyadenylated mRNAs, Histone mRNAs, and U snRNAs by Weiner, Alan M.

“…The 3′ ends of almost all eukaryotic RNAs are generated by nucleolytic cleavage. Remarkably, three groups now demonstrate that similar or identical…”
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Ubiquitin Recognition by the Cockayne Syndrome Group B Protein: Binding Will Set You Free by Gray, Lucas T., Weiner, Alan M.

“…Transcription-coupled nucleotide excision repair (TC-NER) requires the coordinated efforts of many proteins. In this issue of Molecular Cell, Anindya et al…”
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PGBD5: a neural-specific intron-containing piggyBac transposase domesticated over 500 million years ago and conserved from cephalochordates to humans by Pavelitz, Thomas, Gray, Lucas T, Padilla, Stephanie L, Bailey, Arnold D, Weiner, Alan M

“…piggyBac domain (PGBD) transposons are found in organisms ranging from fungi to humans. Three domesticated piggyBac elements have been described. In the…”
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Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide Complexes by Xiong, Yong, Li, Fang, Wang, Jimin, Weiner, Alan M., Steitz, Thomas A.

“…CCA-adding enzymes catalyze the addition of CCA onto the 3′ terminus of immature tRNAs without using a nucleic acid template and have been divided into two…”
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Role of the C-Terminal Domain of RNA Polymerase II in U2 snRNA Transcription and 3′ Processing by Jacobs, Erica Y., Ogiwara, Ikuo, Weiner, Alan M.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Closely related CC- and A-adding enzymes collaborate to construct and repair the 3'-terminal CCA of tRNA in Synechocystis sp. and Deinococcus radiodurans by Tomita, Kozo, Weiner, Alan M

“…The 3'-terminal CCA sequence of tRNA is faithfully constructed and repaired by the CCA-adding enzyme (ATP(CTP):tRNA nucleotidyltransferase) using CTP and ATP…”
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Crystal Structures of the Bacillus stearothermophilus CCA-Adding Enzyme and Its Complexes with ATP or CTP by Li, Fang, Xiong, Yong, Wang, Jimin, Cho, HyunDae D., Tomita, Kozo, Weiner, Alan M., Steitz, Thomas A.

“…CCA-adding enzymes polymerize CCA onto the 3′ terminus of immature tRNAs without using a nucleic acid template. The 3.0 Å resolution crystal structures of the…”
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Reengineering CCA-adding enzymes to function as (U,G)- or dCdCdA-adding enzymes or poly(C,A) and poly(U,G) polymerases by Cho, HyunDae D, Verlinde, Christophe L.M.J, Weiner, Alan M

“…CCA-adding enzymes build and repair the 3'-terminal CCA sequence of tRNA. These unusual RNA polymerases use either a ribonucleoprotein template (class I) or…”
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