Search Results - "Weinberger, Dov"
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3K3A-Activated Protein C Inhibits Choroidal Neovascularization Growth and Leakage and Reduces NLRP3 Inflammasome, IL-1β, and Inflammatory Cell Accumulation in the Retina
Published in International journal of molecular sciences (26-06-2023)“…3K3A-Activated Protein C (APC) is a recombinant variant of the physiological anticoagulant APC with cytoprotective properties and reduced bleeding risks. We…”
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3K3A-Activated Protein C Prevents Microglia Activation, Inhibits NLRP3 Inflammasome and Limits Ocular Inflammation
Published in International journal of molecular sciences (17-11-2022)“…3K3A-Activated Protein C (APC) is a recombinant variant of the physiological anticoagulant APC with pleiotropic cytoprotective properties albeit without the…”
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3
Scleral cross-linking using riboflavin and ultraviolet-A radiation for prevention of progressive myopia in a rabbit model
Published in Experimental eye research (01-10-2014)“…Our study demonstrates the effect of scleral cross-linking using riboflavin and ultraviolet-A radiation on the development of axial myopia in a rabbit model…”
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4
Degradation of HIF-1alpha under hypoxia combined with induction of Hsp90 polyubiquitination in cancer cells by hypericin: a unique cancer therapy
Published in PloS one (19-09-2011)“…The perihydroxylated perylene quinone hypericin has been reported to possess potent anti-metastatic and antiangiogenic activities, generated by targeting…”
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5
Effect of different lens status on intraocular pressure elevation in patients treated with anti-vascular endothelial growth factor injections
Published in International journal of ophthalmology (18-01-2020)“…To assess the effect of lens status on sustained intraocular pressure (IOP) elevation in patients treated intravitreally with anti-vascular endothelial growth…”
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The Histone Deacetylase Inhibitor AN7, Attenuates Choroidal Neovascularization in a Mouse Model
Published in International journal of molecular sciences (07-02-2019)“…Choroidal neovascularization (CNV) is a complication of age-related macular degeneration and a major contributing factor to vision loss. In this paper, we show…”
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Transcleral approach for closing retinal tears using DuraSeal™ hydrogel sealant
Published in Indian journal of ophthalmology (01-02-2018)“…Purpose: The aim of this study was to evaluate an innovative approach for closing retinal tears using DuraSeal™ (DS) hydrogel sealant in a rabbit model…”
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ApoE4 induces synaptic and ERG impairments in the retina of young targeted replacement apoE4 mice
Published in PloS one (31-05-2013)“…The vertebrate retina, which is part of the central nervous system, is a window into the brain. The present study investigated the extent to which the retina…”
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Laser capsulotomy following cataract surgery: Comparing time to capsulotomy with implantation of two broadly used intraocular lenses
Published in Indian journal of ophthalmology (01-02-2017)“…The aim of this study is to compare the length of time from uneventful cataract surgery using one of two common posterior chamber intraocular lenses (IOLs)…”
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10
Aflibercept clearance through the drainage system in a rat model
Published in International journal of retina and vitreous (08-09-2021)“…Abstract Background As intravitreal anti-VEGF injections became the mainstay of treatment for many retinal diseases, the cause of a secondary sustained…”
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Effect of Subconjunctival and Intraocular Bevacizumab Injections on Corneal Neovascularization in a Mouse Model
Published in Current eye research (01-02-2010)“…Purpose: This study sought to evaluate the efficacy of bevacizumab (Avastin®), an anti-VEGF agent, in the reduction of corneal neovascularization in a rodent…”
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12
Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
Published in Journal of visualized experiments (03-04-2016)“…Myopic individuals, especially those with severe myopia, are at higher-than-normal risk of cataract, glaucoma, retinal detachment and chorioretinal…”
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13
Correlation between Interleukin-6 and Thrombin-Antithrombin III Complex Levels in Retinal Diseases
Published in Current eye research (02-09-2017)“…Purpose: This study aims to evaluate and correlate the levels of interleukin-6 (IL-6) and thrombin-antithrombin III complex (TAT) in the vitreous of patients…”
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Activated Protein C (APC) and 3K3A-APC-Induced Regression of Choroidal Neovascularization (CNV) Is Accompanied by Vascular Endothelial Growth Factor (VEGF) Reduction
Published in Biomolecules (Basel, Switzerland) (26-02-2021)“…The activated protein C (APC) ability to inhibit choroidal neovascularization (CNV) growth and leakage was recently shown in a murine model. A modified APC,…”
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15
Changes in Retinal Function and Cellular Remodeling Following Experimental Retinal Detachment in a Rabbit Model
Published in Journal of ophthalmology (01-01-2017)“…Purpose. To explore functional electroretinographic (ERG) changes and associated cellular remodeling following experimental retinal detachment in a rabbit…”
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Intravitreal bevacizumab as supplemental treatment or monotherapy for severe retinopathy of prematurity
Published in Retina (Philadelphia, Pa.) (01-07-2011)“…To investigate the benefit of intravitreal bevacizumab as supplemental or primary treatment for retinopathy of prematurity. The files of nine consecutive…”
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Retinopathy of Prematurity in Assisted versus Natural Conception and Singleton versus Multiple Births
Published in Ophthalmology (Rochester, Minn.) (01-02-2007)“…Objectives To determine whether the incidence and severity of retinopathy of prematurity (ROP) differs between infants conceived naturally and those born after…”
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VEGF Mediates ApoE4-Induced Neovascularization and Synaptic Pathology in the Choroid and Retina
Published in Current Alzheimer research (01-01-2015)“…Apolipoprotein E4 (apoE4), the most prevalent genetic risk factor for Alzheimer's disease (AD), is associated with neuronal and vascular impairments. Recent…”
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Endothelial Cell Loss During Pterygium Surgery: Importance of Timing of Mitomycin C Application
Published in Cornea (01-09-2009)“…PURPOSE:To determine if the timing of mitomycin C (MMC) application during pterygium surgery affects endothelial cell loss. METHODS:A retrospective,…”
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Effect of Repeated Applanation Tonometry on the Accuracy of Intraocular Pressure Measurements
Published in Current eye research (01-06-2010)“…Purpose: To evaluate the stability of successive applanation tonometry measurements in glaucomatous eyes. Methods: A prospective, comparative, randomized, and…”
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