Search Results - "Weinberg, Rona S."

Hematotoxicity in Workers Exposed to Low Levels of Benzene by Lan, Qing, Zhang, Luoping, Li, Guilan, Vermeulen, Roel, Weinberg, Rona S., Dosemeci, Mustafa, Rappaport, Stephen M., Shen, Min, Alter, Blanche P., Wu, Yongji, Kopp, William, Waidyanatha, Suramya, Rabkin, Charles, Guo, Weihong, Chanock, Stephen, Hayes, Richard B., Linet, Martha, Kim, Sungkyoon, Yin, Songnian, Rothman, Nathaniel, Smith, Martyn T.

“…Benzene is known to have toxic effects on the blood and bone marrow, but its impact at levels below the U.S. occupational standard of 1 part per million (ppm)…”
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Donor chimerism and immune reconstitution following haploidentical transplantation in sickle cell disease by Chu, Yaya, Talano, Julie-An, Baxter-Lowe, Lee Ann, Verbsky, James W, Morris, Erin, Mahanti, Harshini, Ayello, Janet, Keever-Taylor, Carolyn, Johnson, Bryon, Weinberg, Rona S, Shi, Qiuhu, Moore, Theodore B, Fabricatore, Sandra, Grossman, Brenda, van de Ven, Carmella, Shenoy, Shalini, Cairo, Mitchell S

“…We previously reported the initial results of a phase II multicenter transplant trial using haploidentical parental donors for children and aolescents with…”
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Role of epigenetic modifications in normal globin gene regulation and butyrate-mediated induction of fetal hemoglobin by Fathallah, Hassana, Weinberg, Rona S., Galperin, Yelena, Sutton, Millicent, Atweh, George F.

“…Butyrate is a prototype of histone deacetylase inhibitors that is believed to reactivate silent genes by inducing epigenetic modifications. Although butyrate…”
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Broadly neutralizing antibodies target the coronavirus fusion peptide by Dacon, Cherrelle, Tucker, Courtney, Peng, Linghang, Lee, Chang-Chun D, Lin, Ting-Hui, Yuan, Meng, Cong, Yu, Wang, Lingshu, Purser, Lauren, Williams, Jazmean K, Pyo, Chul-Woo, Kosik, Ivan, Hu, Zhe, Zhao, Ming, Mohan, Divya, Cooper, Andrew J R, Peterson, Mary, Skinner, Jeff, Dixit, Saurabh, Kollins, Erin, Huzella, Louis, Perry, Donna, Byrum, Russell, Lembirik, Sanae, Drawbaugh, David, Eaton, Brett, Zhang, Yi, Yang, Eun Sung, Chen, Man, Leung, Kwanyee, Weinberg, Rona S, Pegu, Amarendra, Geraghty, Daniel E, Davidson, Edgar, Douagi, Iyadh, Moir, Susan, Yewdell, Jonathan W, Schmaljohn, Connie, Crompton, Peter D, Holbrook, Michael R, Nemazee, David, Mascola, John R, Wilson, Ian A, Tan, Joshua

“…The potential for future coronavirus outbreaks highlights the need to broadly target this group of pathogens. We used an epitope-agnostic approach to identify…”
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Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern by Cho, Hyeseon, Gonzales-Wartz, Kristina Kay, Huang, Deli, Yuan, Meng, Peterson, Mary, Liang, Janie, Beutler, Nathan, Torres, Jonathan L, Cong, Yu, Postnikova, Elena, Bangaru, Sandhya, Talana, Chloe Adrienna, Shi, Wei, Yang, Eun Sung, Zhang, Yi, Leung, Kwanyee, Wang, Lingshu, Peng, Linghang, Skinner, Jeff, Li, Shanping, Wu, Nicholas C, Liu, Hejun, Dacon, Cherrelle, Moyer, Thomas, Cohen, Melanie, Zhao, Ming, Lee, Frances Eun-Hyung, Weinberg, Rona S, Douagi, Iyadh, Gross, Robin, Schmaljohn, Connie, Pegu, Amarendra, Mascola, John R, Holbrook, Michael, Nemazee, David, Rogers, Thomas F, Ward, Andrew B, Wilson, Ian A, Crompton, Peter D, Tan, Joshua

“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern threatens the efficacy of existing vaccines and therapeutic…”
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MPD-RC 101 prospective study of reduced-intensity allogeneic hematopoietic stem cell transplantation in patients with myelofibrosis by Rondelli, Damiano, Goldberg, Judith D., Isola, Luis, Price, Leah S., Shore, Tsiporah B., Boyer, Michael, Bacigalupo, Andrea, Rambaldi, Alessandro, Scarano, Marco, Klisovic, Rebecca B., Gupta, Vikas, Andreasson, Bjorn, Mascarenhas, John, Wetzler, Meir, Vannucchi, Alessandro M., Prchal, Josef T., Najfeld, Vesna, Orazi, Attilio, Weinberg, Rona S., Miller, Crystal, Barosi, Giovanni, Silverman, Lewis R., Prosperini, Giuseppe, Marchioli, Roberto, Hoffman, Ronald

“…From 2007 to 2011, 66 patients with primary myelofibrosis or myelofibrosis (MF) preceded by essential thrombocythemia or polycythemia vera were enrolled into a…”
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Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses by Dacon, Cherrelle, Peng, Linghang, Lin, Ting-Hui, Tucker, Courtney, Lee, Chang-Chun D., Cong, Yu, Wang, Lingshu, Purser, Lauren, Cooper, Andrew J.R., Williams, Jazmean K., Pyo, Chul-Woo, Yuan, Meng, Kosik, Ivan, Hu, Zhe, Zhao, Ming, Mohan, Divya, Peterson, Mary, Skinner, Jeff, Dixit, Saurabh, Kollins, Erin, Huzella, Louis, Perry, Donna, Byrum, Russell, Lembirik, Sanae, Murphy, Michael, Zhang, Yi, Yang, Eun Sung, Chen, Man, Leung, Kwanyee, Weinberg, Rona S., Pegu, Amarendra, Geraghty, Daniel E., Davidson, Edgar, Doranz, Benjamin J., Douagi, Iyadh, Moir, Susan, Yewdell, Jonathan W., Schmaljohn, Connie, Crompton, Peter D., Mascola, John R., Holbrook, Michael R., Nemazee, David, Wilson, Ian A., Tan, Joshua

“…Humanity has faced three recent outbreaks of novel betacoronaviruses, emphasizing the need to develop approaches that broadly target coronaviruses. Here, we…”
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Validation of simple prediction algorithms to consistently achieve CD3+ and postselection CD34+ targets with leukapheresis by Yoon, Edward J., Zhang, Jiahao, Weinberg, Rona S., Brochstein, Joel A., Nandi, Vijay, Sachais, Bruce S., Shi, Patricia A.

“…BACKGROUND Cellular therapies using engineered T cells, haploidentical transplants, and autologous gene therapy are increasing. Specified CD3+ or high CD34+…”
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Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses by Dacon, Cherrelle, Peng, Linghang, Lin, Ting-Hui, Tucker, Courtney, Lee, Chang-Chun D., Cong, Yu, Wang, Lingshu, Purser, Lauren, Cooper, Andrew J.R., Williams, Jazmean K., Pyo, Chul-Woo, Yuan, Meng, Kosik, Ivan, Hu, Zhe, Zhao, Ming, Mohan, Divya, Peterson, Mary, Skinner, Jeff, Dixit, Saurabh, Kollins, Erin, Huzella, Louis, Perry, Donna, Byrum, Russell, Lembirik, Sanae, Murphy, Michael, Zhang, Yi, Yang, Eun Sung, Chen, Man, Leung, Kwanyee, Weinberg, Rona S., Pegu, Amarendra, Geraghty, Daniel E., Davidson, Edgar, Doranz, Benjamin J., Douagi, Iyadh, Moir, Susan, Yewdell, Jonathan W., Schmaljohn, Connie, Crompton, Peter D., Mascola, John R., Holbrook, Michael R., Nemazee, David, Wilson, Ian A., Tan, Joshua

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Butyrate increases the efficiency of translation of γ-globin mRNA by Weinberg, Rona S., Ji, Xinjun, Sutton, Millicent, Perrine, Susan, Galperin, Yelena, Li, Qiliang, Liebhaber, Stephen A., Stamatoyannopoulos, George, Atweh, George F.

“…Fetal hemoglobin (Hb F) levels increase in most patients with sickle cell disease following intermittent butyrate therapy. Although the full effects of…”
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Impact of High-Molecular-Risk Mutations on Transplantation Outcomes in Patients with Myelofibrosis by Tamari, Roni, Rapaport, Franck, Zhang, Nan, McNamara, Caroline, Kuykendall, Andrew, Sallman, David A., Komrokji, Rami, Arruda, Andrea, Najfeld, Vesna, Sandy, Lonette, Medina, Juan, Litvin, Rivka, Famulare, Christopher A., Patel, Minal A., Maloy, Molly, Castro-Malaspina, Hugo, Giralt, Sergio A., Weinberg, Rona S., Mascarenhas, John O., Mesa, Ruben, Rondelli, Damiano, Dueck, Amylou C., Levine, Ross L., Gupta, Vikas, Hoffman, Ronald, Rampal, Raajit K.

“…•In this retrospective analysis, high-risk molecular mutations were found to not affect outcomes of patients with myelofibrosis (MF) undergoing allogeneic…”
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Polymorphisms in cytokine and cellular adhesion molecule genes and susceptibility to hematotoxicity among workers exposed to benzene by QING LAN, LUOPING ZHANG, DOSEMECI, Mustafa, ALTER, Blanche P, WEINBERG, Rona S, SONGNIAN YIN, YEAGER, Meredith, WELCH, Robert, WAIDYANATHA, Suramya, KIM, Sungkyoon, CHANOCK, Stephen, ROTHMAN, Nathaniel, MIN SHEN, SMITH, Martyn T, GUILAN LI, VERMEULEN, Roel, RAPPAPORT, Stephen M, FORREST, Matthew S, HAYES, Richard B, LINET, Martha

“…Benzene is a recognized hematotoxin and leukemogen but its mechanism of action and the role of genetic susceptibility are still unclear. Cytokines, chemokines,…”
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Hemoglobinopathies by Atweh, George F, DeSimone, Joseph, Saunthararajah, Yogen, Fathallah, Hassana, Weinberg, Rona S, Nagel, Ronald L, Fabry, Mary E, Adams, Robert J

“…The outlook for patients with sickle cell disease has improved steadily during the last two decades. In spite of these improvements, curative therapies are…”
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Second generation knockout sickle mice: the effect of HbF by Fabry, Mary E., Suzuka, Sandra M., Weinberg, Rona S., Lawrence, Christine, Factor, Stephen M., Gilman, John G., Costantini, Frank, Nagel, Ronald L.

“…Sickle transgenic mice expressing exclusively human globins are desirable for studying pathophysiology and testing gene therapy strategies, but they must have…”
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Overview of Cellular Therapy by Weinberg, Rona S., PhD

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Hematopoietic Progenitor Cell Products Derived From Bone Marrow and Peripheral Blood by Weinberg, Rona S., PhD

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Recovery of Highly Functional Human Hematopoietic Stem and Progenitor Cells from 27-Year Old Cryopreserved Umbilical Cord Blood by Broxmeyer, Hal E., Luchsinger, Larry L, Weinberg, Rona S, Jimenez, Alexandra, Masson Frenet, Emeline, Kaplan, Mark, Cooper, Scott, Ropa, James

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Syngeneic stem cell transplant for spent‐phase polycythaemia vera: eradication of myelofibrosis and restoration of normal haematopoiesis by Richard, Shambavi, Isola, Luis, Scigliano, Eileen, Singh, Harvinder, Najfeld, Vesna, Gilbert, Harriet, Weinberg, Rona S., Fruchtman, Steven

“…We report a patient with spent‐phase polycythaemia vera (S‐PV) and massive splenomegaly who failed to engraft after a syngeneic granulocyte colony‐stimulating…”
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In Vivo Silencing of the Human γ-Globin Gene in Murine Erythroid Cells Following Retroviral Transduction by Lung, Hui-yu, Meeus, Ilse S, Weinberg, Rona S, Atweh, George F

“…ABSTRACT Increased expression of fetal hemoglobin can ameliorate the clinical severity of sickle cell disease. Whereas temporary induction of fetal hemoglobin…”
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Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system by JIE DAI, WEINBERG, R. S, WAXMAN, S, YONGKUI JING

“…Arsenic trioxide (As2O3) induces clinical remission in acute promyelocytic leukemia (APL) with minimal toxicity and apoptosis in APL-derived NB4 cells at low…”
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