Search Results - "Weinberg, R B"
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Bitter taster status predicts susceptibility to vection-induced motion sickness and nausea
Published in Neurogastroenterology and motility (01-02-2012)“…Background Sensitivity to bitter taste and susceptibility to nausea are both protective mechanisms that guard against toxin ingestion, and both these traits…”
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Efflux of lipid from fibroblasts to apolipoproteins: dependence on elevated levels of cellular unesterified cholesterol
Published in Journal of lipid research (01-11-1992)“…Earlier work from this laboratory showed that enrichment of cells with free cholesterol enhanced the efflux of phospholipid to lipoprotein acceptors,…”
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Identification of functional domains in the plasma apolipoproteins by analysis of inter-species sequence variability
Published in Journal of lipid research (01-12-1994)“…Molecular evolution theory posits that sequence motifs essential for protein function are constrained by selective pressure from changing over long stretches…”
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Effect of the apolipoprotein A-IV Q360H polymorphism on postprandial plasma triglyceride clearance
Published in Journal of lipid research (01-02-2001)“…Apolipoprotein (apo)A-IV is synthesized in the small intestine during fat absorption and is incorporated onto the surface of nascent chylomicrons. In…”
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Apolipoprotein A-IV-2 allele: Association of its worldwide distribution with adult persistence of lactase and speculation on its function and origin
Published in Genetic epidemiology (01-11-1999)“…Apolipoprotein A‐IV (apo A‐IV) is a 46‐Kd plasma glycoprotein that may play a major role in intestinal lipid absorption. A genetic polymorphism in the apo A‐IV…”
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Attenuated hypercholesterolemic response to a high-cholesterol diet in subjects heterozygous for the apolipoprotein A-IV-2 allele
Published in The New England journal of medicine (15-09-1994)“…Background. Previous studies have suggested that the variant apolipoprotein (apo) allele apo A-IV-2 may influence the response of the plasma cholesterol…”
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Adsorption of apolipoprotein A-IV to phospholipid monolayers spread at the air/water interface. A model for its labile binding to high density lipoproteins
Published in The Journal of biological chemistry (05-05-1992)“…The mechanisms that mediate the labile binding of apolipoprotein A-IV (apoA-IV) to high density lipoproteins (HDL) are not known. We therefore used a surface…”
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Distinctive structure and function of human apolipoprotein variant ApoA-IV-2
Published in The Journal of biological chemistry (25-10-1990)“…We have investigated the molecular structure, phospholipid binding, and lecithin-cholesterol acyltransferase catalytic activity of pure apoA-IV-2, a basic…”
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Effect of apolipoprotein A-IV genotype and dietary fat on cholesterol absorption in humans
Published in Journal of lipid research (01-12-2000)“…We investigated the effect of the A-IV-2 allele, which encodes a Q360H substitution in apolipoprotein (apo) A-IV, and dietary fat on cholesterol absorption in…”
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Structural properties and lipid binding of human apolipoprotein A-IV
Published in The Journal of biological chemistry (25-04-1985)“…The in vivo affinity of human apolipoprotein A-IV (apo-A-IV) for plasma lipoproteins is considerably less than that of other apolipoproteins. We have therefore…”
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Bioavailability and efficacy of omeprazole given orally and by nasogastric tube
Published in Digestive diseases and sciences (01-03-1996)“…We compared the bioavailability and the efficacy of omeprazole provided either as encapsulated enteric-coated granules or as enteric-coated granules delivered…”
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Effects of phospholipid on the structure of human apolipoprotein A-IV
Published in The Journal of biological chemistry (15-05-1990)“…We have used fluorescence and circular dichroism spectroscopy to investigate the effect of phospholipid on the structure and molecular stability of human…”
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Interfacial properties of recombinant human cholesterol ester transfer protein
Published in The Journal of biological chemistry (25-11-1994)“…We investigated the interfacial behavior of recombinant human cholesterol ester transfer protein (rCETP) using monolayer and surface balance techniques. rCETP…”
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Sensitivity of serum apolipoprotein A-IV levels to changes in dietary fat content
Published in Gastroenterology (New York, N.Y. 1943) (01-01-1990)“…The distinctive biological properties of apolipoprotein A-IV suggest that its concentration in serum should be specifically regulated by dietary triglyceride…”
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Human apolipoprotein A-IV: displacement from the surface of triglyceride-rich particles by HDL2-associated C-apoproteins
Published in Journal of lipid research (01-01-1985)“…Human apolipoprotein A-IV rapidly dissociates from the surface of lymph chylomicrons following their entry into circulation by an unknown mechanism. We have…”
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Isolation and characterization of human apolipoprotein A-IV from lipoprotein-depleted serum
Published in Journal of lipid research (01-01-1983)“…Human apolipoprotein A-IV is an acidic polypeptide of molecular weight 46,000 that is secreted into lymph on the surface of nascent chylomicrons, but which…”
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The self-association of human apolipoprotein A-IV. Evidence for an in vivo circulating dimeric form
Published in The Journal of biological chemistry (15-11-1985)“…We have investigated the self-association properties of human apolipoprotein A-IV using several complementary physical techniques. Sedimentation equilibrium…”
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