Search Results - "Weinberg, Jason"
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The immunoproteasome and viral infection: a complex regulator of inflammation
Published in Frontiers in microbiology (29-01-2015)“…During viral infection, proper regulation of immune responses is necessary to ensure successful viral clearance with minimal host tissue damage. Proteasomes…”
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Gut dysbiosis promotes M2 macrophage polarization and allergic airway inflammation via fungi-induced PGE
Published in Cell host & microbe (15-01-2014)“…Although imbalances in gut microbiota composition, or "dysbiosis," are associated with many diseases, the effects of gut dysbiosis on host systemic physiology…”
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Gut Dysbiosis Promotes M2 Macrophage Polarization and Allergic Airway Inflammation via Fungi-Induced PGE2
Published in Cell host & microbe (15-01-2014)“…Although imbalances in gut microbiota composition, or “dysbiosis,” are associated with many diseases, the effects of gut dysbiosis on host systemic physiology…”
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4
Risk of Staphylococcus aureus Bacteremia Before and After Solid Organ Transplantation
Published in Transplantation (01-08-2023)“…Solid organ transplant recipients are at high risk for Staphylococcus aureus bacteremia, but the risks before and after transplantation require further…”
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Neurodevelopmental outcomes of children with congenital cytomegalovirus: a systematic scoping review
Published in Pediatric research (01-01-2024)“…Background With the emergence of newborn congenital cytomegalovirus (cCMV) screening programs, more infants are being diagnosed and require long-term…”
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Nephrotoxicity of Intravenous Ganciclovir in Pediatric Hematopoietic Cell Transplant Recipients
Published in The Pediatric infectious disease journal (23-07-2024)“…Associations between ganciclovir and severe nephrotoxicity are incompletely defined. Studies incorporating the time-varying nature of medication exposures and…”
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Emerging antiviral therapeutics for human adenovirus infection: Recent developments and novel strategies
Published in Antiviral research (01-04-2021)“…Human adenoviruses (HAdV) are ubiquitous human pathogens that cause a significant burden of respiratory, ocular, and gastrointestinal illnesses. Although HAdV…”
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Adenoviruses in medicine: innocuous pathogen, predator, or partner
Published in Trends in molecular medicine (01-01-2023)“…The consequences of human adenovirus (HAdV) infections are generally mild. However, despite the perception that HAdVs are harmless, infections can cause severe…”
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Inhibition of Human Adenovirus Replication by the Importin α/β1 Nuclear Import Inhibitor Ivermectin
Published in Journal of virology (31-08-2020)“…Human adenoviruses (HAdV) are ubiquitous within the human population and comprise a significant burden of respiratory illnesses worldwide. Pediatric and…”
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Effects of tumor necrosis factor on viral replication and pulmonary inflammation during acute mouse adenovirus type 1 respiratory infection
Published in Virology (New York, N.Y.) (01-08-2020)“…CD8 T cells contribute to effective clearance of mouse adenovirus type 1 (MAV-1) and to virus-induced pulmonary inflammation. We characterized effects of a CD8…”
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Daily Fevers, Pancytopenia, and Elevated Transaminase Levels in a 5-month-old Boy
Published in Pediatrics in review (01-12-2022)Get full text
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Hyperoxia/Hypoxia Exposure Primes a Sustained Pro-Inflammatory Profile of Preterm Infant Macrophages Upon LPS Stimulation
Published in Frontiers in immunology (18-11-2021)“…Preterm infants are highly susceptible to sustained lung inflammation, which may be triggered by exposure to multiple environmental cues such as supplemental…”
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Mouse Adenovirus Type 1 Persistence Exacerbates Inflammation Induced by Allogeneic Bone Marrow Transplantation
Published in Journal of virology (23-03-2022)“…Bone marrow transplantation (BMT) recipients are at risk for substantial morbidity and mortality from human adenovirus infections, often in the setting of…”
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Severe Acute Respiratory Syndrome Coronavirus 2: Manifestations of Disease and Approaches to Treatment and Prevention in Humans
Published in Comparative medicine (01-10-2021)“…The coronavirus disease 2019 (COVID-19) pandemic was caused by a novel coronavirus, severe acute respiratory syndromecoronavirus 2 (SARS-CoV-2). This virus has…”
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Fas activity mediates airway inflammation during mouse adenovirus type 1 respiratory infection
Published in Virology (New York, N.Y.) (01-08-2018)“…CD8 T cells play a key role in clearance of mouse adenovirus type 1 (MAV-1) from the lung and contribute to virus-induced airway inflammation. We tested the…”
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IL-17 contributes to neutrophil recruitment but not to control of viral replication during acute mouse adenovirus type 1 respiratory infection
Published in Virology (New York, N.Y.) (01-05-2014)“…Abstract IL-17-producing CD4+ helper T cells (Th17 cells) promote inflammatory responses to many pathogens. We used mouse adenovirus type 1 (MAV-1) to…”
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Alveolar Epithelial Cell-Derived Prostaglandin E2 Serves as a Request Signal for Macrophage Secretion of Suppressor of Cytokine Signaling 3 during Innate Inflammation
Published in The Journal of immunology (1950) (15-06-2016)“…Preservation of gas exchange mandates that the pulmonary alveolar surface restrain unnecessarily harmful inflammatory responses to the many challenges to which…”
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Age-Dependent Effects of Immunoproteasome Deficiency on Mouse Adenovirus Type 1 Pathogenesis
Published in Journal of virology (01-08-2019)“…Acute respiratory infection with mouse adenovirus type 1 (MAV-1) induces activity of the immunoproteasome, an inducible form of the proteasome that shapes CD8…”
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Prostaglandin E2 Production and T Cell Function in Mouse Adenovirus Type 1 Infection following Allogeneic Bone Marrow Transplantation
Published in PloS one (25-09-2015)“…Adenovirus infections are important complications of bone marrow transplantation (BMT). We demonstrate delayed clearance of mouse adenovirus type 1 (MAV-1)…”
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Advance Care Planning in an Accountable Care Organization Is Associated with Increased Advanced Directive Documentation and Decreased Costs
Published in Journal of palliative medicine (01-04-2018)“…Advance care planning (ACP) documents patient wishes and increases awareness of palliative care options. To study the association of outpatient ACP with…”
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