Search Results - "Weimar, Willem"

Tacrolimus inhibits NF-κB activation in peripheral human T cells by Vafadari, Ramin, Kraaijeveld, Rens, Weimar, Willem, Baan, Carla C

“…The calcineurin inhibitor, tacrolimus (TAC), inhibits the protein phosphatase activity of calcineurin, leading to suppression of the nuclear translocation of…”
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Hepatitis E virus infection among solid organ transplant recipients, the Netherlands by Pas, Suzan D, de Man, Rob A, Mulders, Claudia, Balk, Aggie H M M, van Hal, Peter T W, Weimar, Willem, Koopmans, Marion P G, Osterhaus, Albert D M E, van der Eijk, Annemiek A

“…We screened 1,200 living heart, lung, liver, and kidney transplant recipients for hepatitis E virus infection by reverse transcription PCR. In 12 (1%)…”
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Long-term prognosis after kidney donation: a propensity score matched comparison of living donors and non-donors from two population cohorts by Janki, Shiromani, Dehghan, Abbas, van de Wetering, Jacqueline, Steyerberg, Ewout W., Klop, Karel W. J., Kimenai, Hendrikus J. A. N., Rizopoulos, Dimitris, Hoorn, Ewout J., Stracke, Sylvia, Weimar, Willem, Völzke, Henry, Hofman, Albert, Ijzermans, Jan N. M.

“…Background Live donor nephrectomy is a safe procedure. However, long-term donor prognosis is debated, necessitating high-quality studies. Methods A follow-up…”
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Down-Regulation of Surface CD28 under Belatacept Treatment: An Escape Mechanism for Antigen-Reactive T-Cells by de Graav, Gretchen N, Hesselink, Dennis A, Dieterich, Marjolein, Kraaijeveld, Rens, Weimar, Willem, Baan, Carla C

“…The co-stimulatory inhibitor of the CD28-CD80/86-pathway, belatacept, allows calcineurin-inhibitor-free immunosuppression in kidney transplantation. However,…”
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Boosting the VZV-Specific Memory B and T Cell Response to Prevent Herpes Zoster After Kidney Transplantation by Kho, Marcia M. L., Weimar, Willem, Malahe, S. Reshwan K., Zuijderwijk, Joke M., de Kuiper, Ronella, Boer-Verschragen, Marieken J., Eijk, Annemiek A. van der, Hesselink, Dennis A., Reinders, Marlies E. J., van Besouw, Nicole M.

“…Background Solid organ transplant recipients are at high risk to develop (complicated) herpes zoster (HZ). Booster vaccination could prevent HZ. However,…”
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Reflections of unspecified anonymous kidney donors on their motivation and the impact of donation on their mental health: A qualitative study by Pronk, Mathilde C., Zuidema, Willij, Weimar, Willem, van de Wetering, Jacqueline, Ismail, Sohal Y., Massey, Emma K.

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Effects of Hypoxia on the Immunomodulatory Properties of Adipose Tissue-Derived Mesenchymal Stem cells by Roemeling-van Rhijn, Marieke, Mensah, Fane K F, Korevaar, Sander S, Leijs, Maarten J, van Osch, Gerjo J V M, Ijzermans, Jan N M, Betjes, Michiel G H, Baan, Carla C, Weimar, Willem, Hoogduijn, Martin J

“…Adipose tissue-derived mesenchymal stem cells (ASC) are of great interest as a cellular therapeutic agent for regenerative and immunomodulatory purposes. The…”
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Human mesenchymal stem cells are susceptible to lysis by CD8(+) T cells and NK cells by Crop, Meindert J, Korevaar, Sander S, de Kuiper, Ronella, IJzermans, Jan N M, van Besouw, Nicole M, Baan, Carla C, Weimar, Willem, Hoogduijn, Martin J

“…There is growing interest in the use of mesenchymal stem cells (MSCs) to improve the outcome of organ transplantation. The immunogenicity of MSCs is, however,…”
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Belatacept Does Not Inhibit Follicular T Cell-Dependent B-Cell Differentiation in Kidney Transplantation by de Graav, Gretchen N, Hesselink, Dennis A, Dieterich, Marjolein, Kraaijeveld, Rens, Verschoor, Wenda, Roelen, Dave L, Litjens, Nicolle H R, Chong, Anita S, Weimar, Willem, Baan, Carla C

“…Humoral alloreactivity has been recognized as a common cause of kidney transplant dysfunction. B-cell activation, differentiation, and antibody production are…”
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Interaction between adipose tissue-derived mesenchymal stem cells and regulatory T-cells by Engela, Anja U, Baan, Carla C, Peeters, Annemiek M A, Weimar, Willem, Hoogduijn, Martin J

“…Mesenchymal stem cells (MSCs) exhibit immunosuppressive capabilities, which have evoked interest in their application as cell therapy in transplant patients…”
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Independent risk factors for urological complications after deceased donor kidney transplantation by Slagt, Inez K B, Ijzermans, Jan N M, Visser, Laurents J, Weimar, Willem, Roodnat, Joke I, Terkivatan, Türkan

“…Urological complications after kidney transplantation are mostly related to the ureteroneocystostomy, often requiring interventions with additional costs,…”
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Three‐Year Efficacy and Safety Results from a Study of Everolimus Versus Mycophenolate Mofetil in de novo Renal Transplant Patients by Vítko, Štefan, Margreiter, Raimund, Weimar, Willem, Dantal, Jacques, Kuypers, Dirk, Winkler, Michael, Øyen, Ole, Viljoen, Hendrik G., Filiptsev, Pavel, Sadek, Sami, Li, Yulan, Cretin, Nathalie, Budde, Klemens

“…Everolimus 1.5 or 3 mg/day was compared with mycophenolate mofetil (MMF) 2 g/day in a randomized, multicenter 36‐month trial in de novo renal allograft…”
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Genetic Polymorphisms in ABCB1 Influence the Pharmacodynamics of Tacrolimus by VAFADARI, Ramin, BOUAMAR, Rachida, HESSELINK, Dennis A, KRAAIJEVELD, Rens, VAN SCHAIK, Ron H. N, WEIMAR, Willem, BAAN, Carla C, VAN GELDER, Teun

“…Tacrolimus has a large interindividual pharmacokinetic variability, and quantification of its effect is difficult. It is a substrate of ABCB1, an efflux pump…”
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Comparison of a home-based (multi) systemic intervention to promoting Medication AdheRence and Self-management among kidney transplant recipients with care-as-usual: the MARS randomized controlled trial protocol by Beck, Denise Karin, Tielen, Mirjam, Rechards, Marloes, Timman, Reinier, Boonstra, Charlotte, Versteegh, Josette, van de Wetering, Jacqueline, Zietse, Robert, van Gelder, Teun, Weimar, Willem, van Saase, Jan, van Busschbach, Jan, Massey, Emma Kay

“…After kidney transplantation non-adherence and inadequate self-management undermine clinical outcomes and quality of life. Both have been demonstrated to be…”
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Everolimus (certican) 12-month safety and efficacy versus mycophenolate mofetil in de novo renal transplant recipients by VITKO, Stefan, MARGREITER, Raimund, WEIMAR, Willem, DANTAL, Jacques, VILJOEN, Hendrik G, YULAN LI, JAPPE, Annette, CRETIN, Nathalie

“…Everolimus is a proliferation inhibitor designed to target chronic rejection, including prevention of acute rejection. Everolimus blocks growth factor-mediated…”
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Uremia causes premature ageing of the T cell compartment in end-stage renal disease patients by Meijers, Ruud Wj, Litjens, Nicolle Hr, de Wit, Elly A, Langerak, Anton W, van der Spek, Ashley, Baan, Carla C, Weimar, Willem, Betjes, Michiel Gh

“…End-stage renal disease (ESRD) patients treated with renal replacement therapy (RRT) have premature immunologically aged T cells which may underlie…”
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A shift towards pro-inflammatory CD16+ monocyte subsets with preserved cytokine production potential after kidney transplantation by Vereyken, Elly J F, Kraaij, Marina D, Baan, Carla C, Rezaee, Farhad, Weimar, Willem, Wood, Kathryn J, Leenen, Pieter J M, Rowshani, Ajda T

“…The presence of monocyte-macrophage lineage cells in rejecting kidney transplants is associated with worse graft outcome. At present, it is still unclear how…”
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The Dutch National Living Donor Kidney Exchange Program by De Klerk, Marry, Keizer, Karin M., Claas, Frans H. J., Witvliet, Marian, Haase‐Kromwijk, Bernadette J. J. M., Weimar, Willem

“…The wait time for deceased‐donor kidney transplantation has increased to 4–5 years in the Netherlands. Strategies to expand the donor pool include a living…”
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FTY720, a novel immunomodulator: Efficacy and safety results from the first phase 2A study in de novo renal transplantation by TEDESCO-SILVA, Helio, MOURAD, Georges, VANRENTERGHEM, Yves, KAHAN, Barry D, GRINYO BOIRA, Josep, WEIMAR, Willem, MULGAONKAR, Shamkant, NASHAN, Björn, MADSEN, Soren, CHARPENTIER, Bernard, PELLET, Pascale

“…FTY720 is the first of a new drug class: sphingosine-1-phosphate receptor agonist. Its effect relates to the modulation of lymphocytes trafficking from blood…”
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Response: Commentary: Belatacept Does Not Inhibit Follicular T Cell-Dependent B-Cell Differentiation in Kidney Transplantation by Baan, Carla C, de Graav, Gretchen N, Weimar, Willem, Hesselink, Dennis A

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