Search Results - "Weill, Laure"
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Translational control by changes in poly(A) tail length: recycling mRNAs
Published in Nature structural & molecular biology (01-06-2012)“…Recent studies have revealed how poly(A) tail length and the selection of alternative polyadenylation sites contribute to translational control. This Review…”
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2
Evolution of Somite Compartmentalization: A View From Xenopus
Published in Frontiers in cell and developmental biology (17-01-2022)“…Somites are transitory metameric structures at the basis of the axial organization of vertebrate musculoskeletal system. During evolution, somites appear in…”
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3
The analysis of the skeletal muscle metabolism is crucial for designing optimal exercise paradigms in type 2 diabetes mellitus
Published in Molecular medicine (Cambridge, Mass.) (10-06-2024)“…Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that commonly results from a high-calorie diet and sedentary lifestyle, leading to insulin…”
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4
Involvement of Aryl hydrocarbon receptor in myelination and in human nerve sheath tumorigenesis
Published in Proceedings of the National Academy of Sciences - PNAS (06-02-2018)“…Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor involved in xenobiotic metabolism. Plexiform neurofibromas (PNFs) can transform into…”
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5
NADPH oxidase 4 inhibition is a complementary therapeutic strategy for spinal muscular atrophy
Published in Frontiers in cellular neuroscience (14-09-2023)“…Introduction Spinal muscular atrophy (SMA) is a fatal neurodegenerative disorder, characterized by motor neuron (MN) degeneration and severe muscular atrophy…”
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Low-Intensity Running and High-Intensity Swimming Exercises Differentially Improve Energy Metabolism in Mice With Mild Spinal Muscular Atrophy
Published in Frontiers in physiology (01-10-2019)“…Spinal Muscular Atrophy (SMA), an autosomal recessive neurodegenerative disease characterized by the loss of spinal-cord motor-neurons, is caused by mutations…”
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Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice
Published in Frontiers in molecular neuroscience (20-10-2017)“…Amyotrophic Lateral Sclerosis is an adult-onset neurodegenerative disease characterized by the specific loss of motor neurons, leading to muscle paralysis and…”
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Musashi 1 regulates the timing and extent of meiotic mRNA translational activation by promoting the use of specific CPEs
Published in Nature structural & molecular biology (01-08-2017)“…New data reveal how Musashi binding to Xenopus oocyte mRNAs promotes changes in RNA secondary structure that modulate CPEB1 binding and influence…”
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Xenopus SOX5 enhances myogenic transcription indirectly through transrepression
Published in Developmental biology (15-10-2018)“…In anamniotes, somite compartimentalization in the lateral somitic domain leads simultaneously to myotome and dermomyotome formation. In the myotome, Xenopus…”
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Author Correction: Musashi 1 regulates the timing and extent of meiotic mRNA translational activation by promoting the use of specific CPEs
Published in Nature structural & molecular biology (01-08-2019)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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11
Lineage tracing of sclerotome cells in amphibian reveals that multipotent somitic cells originate from lateral somitic frontier
Published in Developmental biology (01-09-2019)“…The two somite compartments, dorso-lateral dermomyotome and medio-ventral sclerotome are major vertebrate novelties, but little is known about their…”
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12
Dysregulation of muscle cholesterol transport in amyotrophic lateral sclerosis
Published in Brain (London, England : 1878) (28-08-2024)“…Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder affecting motor neurons, with a typical lifespan of 3-5 years. Altered…”
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13
Activating ATF6 in spinal muscular atrophy promotes SMN expression and motor neuron survival through the IRE1α‐XBP1 pathway
Published in Neuropathology and applied neurobiology (01-08-2022)“…Aim Spinal muscular atrophy (SMA) is a neuromuscular disease caused by survival of motor neuron (SMN) deficiency that induces motor neuron (MN) degeneration…”
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14
IGF-1R Reduction Triggers Neuroprotective Signaling Pathways in Spinal Muscular Atrophy Mice
Published in The Journal of neuroscience (26-08-2015)“…Spinal muscular atrophy (SMA) is a neuromuscular disease characterized by the selective loss of spinal motor neurons due to the depletion of the survival of…”
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15
A new type of IRES within gag coding region recruits three initiation complexes on HIV-2 genomic RNA
Published in Nucleic acids research (01-03-2010)“…Genomic RNA of primate lentiviruses serves both as an mRNA that encodes Gag and Gag-Pol polyproteins and as a propagated genome. Translation of this RNA is…”
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16
IGF-1 R Reduction Triggers Neuroprotective Signaling Pathways in Spinal Muscular Atrophy Mice
Published in The Journal of neuroscience (06-08-2015)“…Spinal muscular atrophy (SMA) is a neuromuscular disease characterized by the selective loss of spinal motor neurons due to the depletion of the survival of…”
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17
HIV-2 genomic RNA contains a novel type of IRES located downstream of its initiation codon
Published in Nature structural & molecular biology (01-11-2005)“…Eukaryotic translation initiation begins with assembly of a 48S ribosomal complex at the 5' cap structure or at an internal ribosomal entry segment (IRES). In…”
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18
Transcription factor YY1 binds to the murine beta interferon promoter and regulates its transcriptional capacity with a dual activator/repressor role
Published in Journal of virology (01-03-2003)“…The induction of the beta interferon (IFN-beta) gene constitutes one of the first responses of the cell to virus infection. Its regulation is achieved through…”
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Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice
Published in Frontiers in molecular neuroscience (20-10-2017)Get full text
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20
Selection and evolution of NTP-specific aptamers
Published in Nucleic acids research (01-01-2004)“…ATP occupies a central position in biology, for it is both an elementary building block of RNA and the most widely used cofactor in all living organisms. For…”
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