Search Results - "Weilenmann, C."
-
1
Calcium-calmodulin dependent protein kinase II (CaMKII): A main signal responsible for early reperfusion arrhythmias
Published in Journal of molecular and cellular cardiology (01-12-2011)“…Abstract To explore whether CaMKII-dependent phosphorylation events mediate reperfusion arrhythmias, Langendorff perfused hearts were submitted to global…”
Get full text
Journal Article -
2
Early effects of Epac depend on the fine-tuning of the sarcoplasmic reticulum Ca2+ handling in cardiomyocytes
Published in Journal of molecular and cellular cardiology (01-01-2018)“…In cardiac muscle, signaling through cAMP governs many fundamental cellular functions, including contractility, relaxation and automatism. cAMP cascade leads…”
Get full text
Journal Article -
3
Increased intracellular Ca2+ and SR Ca2+ load contribute to arrhythmias after acidosis in rat heart. Role of Ca2+/calmodulin-dependent protein kinase II
Published in American journal of physiology. Heart and circulatory physiology (01-10-2008)“…Returning to normal pH after acidosis, similar to reperfusion after ischemia, is prone to arrhythmias. The type and mechanisms of these arrhythmias have never…”
Get more information
Journal Article -
4
Allergy to betalactam antibiotics in children: a prospective follow‐up study in retreated children after negative responses in skin and challenge tests
Published in Allergy (Copenhagen) (01-01-2007)“…Background: Up to 10% of the patients in whom suspected betalactam hypersensitivity (HS) has been excluded by skin and challenge tests report suspected…”
Get full text
Journal Article -
5
Role of dual-site phospholamban phosphorylation in the stunned heart: insights from phospholamban site-specific mutants
Published in American journal of physiology. Heart and circulatory physiology (01-09-2003)“…Phosphorylation of phospholamban (PLB) at Ser16 (protein kinase A site) and at Thr17 [Ca2+/calmodulin kinase II (CaMKII) site] increases sarcoplasmic reticulum…”
Get more information
Journal Article -
6
Phosphorylation of phospholamban in ischemia-reperfusion injury: Functional role of Thr(17) residue
Published in Molecular and cellular biochemistry (01-08-2004)“…Phospholamban (PLB) is a sarcoplasmic reticulum (SR) protein that when phosphorylated at Ser(16) by PKA and/or at Thr(17) by CaMKII increases the affinity of…”
Get full text
Journal Article -
7
Increased brain radioactivity by intranasal 32P-labeled siRNA dendriplexes within in situ-forming mucoadhesive gels
Published in International journal of nanomedicine (01-03-2012)“…Background: Molecules taken up by olfactory and trigeminal nerve neurons directly access the brain by the nose-to-brain pathway. In situ-forming mucoadhesive…”
Get full text
Journal Article -
8
The importance of the Thr17 residue of phospholamban as a phosphorylation site under physiological and pathological conditions
Published in Brazilian journal of medical and biological research (01-05-2006)“…The sarcoplasmic reticulum (SR) Ca2+-ATPase (SERCA2a) is under the control of an SR protein named phospholamban (PLN). Dephosphorylated PLN inhibits SERCA2a,…”
Get full text
Journal Article -
9
Effects of acidosis on phosphorylation of phospholamban and troponin I in rat cardiac muscle
Published in The American journal of physiology (01-01-1996)“…Acidosis inhibits Ca2+ transport by the sarcoplasmic reticulum of cardiac muscle and decreases the Ca2+ sensitivity of the contractile proteins, although the…”
Get full text
Journal Article -
10
Mechanisms Involved in the Acidosis Enhancement of the Isoproterenol-induced Phosphorylation of Phospholamban in the Intact Heart
Published in The Journal of biological chemistry (17-04-1998)“…Previous experiments have shown that acidosis enhances isoproterenol-induced phospholamban (PHL) phosphorylation (Mundiña-Weilenmann, C., Vittone, L.,…”
Get full text
Journal Article -
11
Endoplasmic reticulum contribution to the relaxant effect of cGMP- and cAMP-elevating agents in feline aorta
Published in American journal of physiology. Heart and circulatory physiology (01-06-2000)“…The contribution of endoplasmic reticulum (ER) and phosphorylation of phospholamban (PLB) to the relaxant effect of cGMP- and cAMP-elevating agents was studied…”
Get more information
Journal Article -
12
Dihydropyridine-sensitive calcium channels from skeletal muscle. II. Functional effects of differential phosphorylation of channel subunits
Published in The Journal of biological chemistry (05-09-1991)“…Dihydropyridine-sensitive Ca2+ channels from skeletal muscle are multisubunit proteins and are regulated by protein phosphorylation. The purpose of this study…”
Get full text
Journal Article -
13
Demonstration of the phosphorylation of dihydropyridine-sensitive calcium channels in chick skeletal muscle and the resultant activation of the channels after reconstitution
Published in The Journal of biological chemistry (05-03-1991)“…We have examined the effects of cAMP elevating agents on the phosphorylation of dihydropyridine-sensitive Ca2+ channels in intact newborn chick skeletal…”
Get full text
Journal Article -
14
Dihydropyridine-sensitive skeletal muscle Ca channels in polarized planar bilayers. 2. Effects of phosphorylation by cAMP-dependent protein kinase
Published in Biophysical journal (01-10-1991)“…The effects of phosphorylation on the voltage-dependent properties of dihydropyridine-sensitive Ca channels of skeletal muscle were studied. Single channel…”
Get full text
Journal Article -
15
Dihydropyridine-sensitive skeletal muscle Ca channels in polarized planar bilayers. 1. Kinetics and voltage dependence of gating
Published in Biophysical journal (01-10-1991)“…Rabbit skeletal muscle transverse tubule (T) membranes were fused with planar bilayers. Ca channel activity was studied with a "cellular" approach, using…”
Get full text
Journal Article -
16
Immunodetection of Phosphorylation Sites of Phospholamban in Aortic Smooth Muscle Effects of Sodium Nitroprusside
Published in Annals of the New York Academy of Sciences (01-09-1998)Get full text
Journal Article -
17
Selective cytotoxicity of PAMAM G5 core--PAMAM G2.5 shell tecto-dendrimers on melanoma cells
Published in International journal of nanomedicine (01-01-2012)“…The controlled introduction of covalent linkages between dendrimer building blocks leads to polymers of higher architectural order known as tecto-dendrimers…”
Get full text
Journal Article -
18
Early effects of Epac depend on the fine-tuning of the sarcoplasmic reticulum Ca 2+ handling in cardiomyocytes
Published in Journal of molecular and cellular cardiology (01-01-2018)“…In cardiac muscle, signaling through cAMP governs many fundamental cellular functions, including contractility, relaxation and automatism. cAMP cascade leads…”
Get full text
Journal Article -
19
Plasmodium falciparum CS C-terminal fragment: preclinical evaluation and phase I clinical studies
Published in Parassitologia (01-09-1999)“…Preclinical evaluation of synthetic peptides corresponding to the C-terminal regions of the circumsporozoite (CS) protein in various Plasmodia showed that…”
Get more information
Journal Article -
20
Selective cytotoxicity of PAMAM G5 core ndash;PAMAM G2.5 shell tecto-dendrimers on melanoma cells
Published in International journal of nanomedicine (01-07-2012)“…Priscila Schilrreff,1 Cecilia Mundiña-Weilenmann,2 Eder Lilia Romero,1 Maria Jose Morilla11Programa de Nanomedicinas, Universidad Nacional de Quilmes,…”
Get full text
Journal Article