Search Results - "Weijian, Bei"
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1
Pathological and therapeutic roles of bioactive peptide trefoil factor 3 in diverse diseases: recent progress and perspective
Published in Cell death & disease (17-01-2022)“…Trefoil factor 3 (TFF3) is the last small-molecule peptide found in the trefoil factor family, which is mainly secreted by intestinal goblet cells and exerts…”
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2
Hesperidin ameliorates insulin resistance by regulating the IRS1‐GLUT2 pathway via TLR4 in HepG2 cells
Published in Phytotherapy research (01-06-2019)“…The aim of this study was to evaluate the effect and mechanism of hesperidin (HES) on insulin resistance (IR) in the human hepatocellular carcinoma cell line…”
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3
FTZ Ameliorates Diabetic Cardiomyopathy by Inhibiting Inflammation and Cardiac Fibrosis in the Streptozotocin-Induced Model
Published in Evidence-based complementary and alternative medicine (2021)“…Background. The pathogenesis and clinical features of diabetic cardiomyopathy (DCM) have been well studied in the past decade; however, effective approaches to…”
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4
The traditional Chinese medicine formula Fufang-Zhenzhu-Tiaozhi protects myocardia from injury in diabetic minipigs with coronary heart disease
Published in Biomedicine & pharmacotherapy (01-05-2021)“…Diabetes mellitus (DM) is a major risk factor for coronary heart disease (CHD). Previous research has reported that the Fufang-Zhenzhu-Tiaozhi (FTZ) formula…”
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5
Ginsenoside Rb1 ameliorates the abnormal hepatic glucose metabolism by activating STAT3 in T2DM mice
Published in Journal of functional foods (01-05-2023)“…[Display omitted] •Ginsenoside Rb1 improves type 2 diabetes mellitus.•Rb1 ameliorates the abnormal hepatic glucose metabolism in T2DM mice.•Rb1 promotes…”
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6
Ginseng extract improves pancreatic islet injury and promotes β-cell regeneration in T2DM mice
Published in Frontiers in pharmacology (25-06-2024)“… (Araliaceae; Ginseng Radix et Rhizoma), a traditional plant commonly utilized in Eastern Asia, has demonstrated efficacy in treating neuro-damaging diseases…”
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7
FTZ attenuates liver steatosis and fibrosis in the minipigs with type 2 diabetes by regulating the AMPK signaling pathway
Published in Biomedicine & pharmacotherapy (01-06-2021)“…Fufang Zhenzhu Tiaozhi formula (FTZ), a preparation of Chinese herbal medicine, has various pharmacological properties, such as hypoglycemic, hypolipidemic,…”
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Chinese medicine Fufang Zhenzhu Tiaozhi capsule ameliorates coronary atherosclerosis in diabetes mellitus-related coronary heart disease minipigs
Published in Biomedicine & pharmacotherapy (01-12-2022)“…Diabetes mellitus-related coronary heart disease (DM-CHD) is the most common cause of death in diabetic patients. Various studies have shown that Chinese…”
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9
Chinese Medicine FTZ Recipe Protects against High-Glucose-Induced Beta Cell Injury through Alleviating Oxidative Stress
Published in Evidence-based complementary and alternative medicine (01-01-2019)“…Objective. To investigate the effect of FTZ on high-glucose-induced oxidative stress and underlying mechanisms. Methods. We used a β cell dysfunction and…”
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10
Hesperidin activates the GLP-1R/cAMP-CREB/IRS2/PDX1 pathway to promote transdifferentiation of islet α cells into β cells Across the spectrum
Published in Heliyon (30-08-2024)“…In all age, FoShou as a Chinese medicinal herb has been active in various kinds of Traditional Chinese medicine formula to treating diabetes. Hesperidin (HES),…”
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11
A new TCM formula FTZ lowers serum cholesterol by regulating HMG-CoA reductase and CYP7A1 in hyperlipidemic rats
Published in Journal of ethnopharmacology (17-05-2011)“…Fufang Zhenzhu Tiao Zhi (FTZ) showed significant hypolipidemic effect by at least three pathways in the high lipid diet induced hyperlipidemic rats: (1)…”
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12
Traditional Chinese Medicine Fufang-Zhenzhu-Tiaozhi capsule prevents renal injury in diabetic minipigs with coronary heart disease
Published in Chinese medicine (30-08-2022)“…Abstract Background Renal injury is one of the common microvascular complications of diabetes, known as diabetic kidney disease (DKD) seriously threatening…”
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13
Oleanolic Acid Attenuates Insulin Resistance via NF-[kappa]B to Regulate the IRS1-GLUT4 Pathway in HepG2 Cells
Published in Evidence-based complementary and alternative medicine (01-01-2016)“…The aim of our study is to elucidate the mechanisms of oleanolic acid (OA) on insulin resistance (IR) in HepG2 cells. HepG2 cells were induced with FFA as the…”
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14
Analysis of the Constituents in Rat Serum after Oral Administration of Fufang Zhenzhu Tiaozhi Capsule by UPLC–Q–TOF–MS/MS
Published in Chromatographia (01-02-2012)“…A rapid and sensitive UPLC/Q–TOF–MS method has been established for analysis of the constituents in rat serum after oral administration of Fufang Zhenzhu…”
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15
Neuroprotective effects of a standardized flavonoid extract from Diospyros kaki leaves
Published in Journal of ethnopharmacology (29-10-2009)“…Flavonoids, extracted from the leaves of Diospyros kaki, are the main therapeutic components of NaoXingQing (NXQ), a potent and patented Chinese herbal remedy…”
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16
Neuroprotective effects of a standardized extract of Diospyros kaki leaves on MCAO transient focal cerebral ischemic rats and cultured neurons injured by glutamate or hypoxia
Published in Planta medica (01-06-2007)“…Naoxinqing (NXQ, a standardized extract of Diospyros kaki leaves) is a patented and approved drug of Traditional Chinese Medicine (TCM) used for the treatment…”
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17
NaoXinQing, an anti-stroke herbal medicine, reduces hydrogen peroxide-induced injury in NG108-15 cells
Published in Neuroscience letters (17-06-2004)“…NaoXinQing (NXQ) is a patented and approved drug of Traditional Chinese Medicine that has been used for years for the treatment of syndrome of apoplexy, but…”
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18
NLRP3 inflammasome and IL-1β pathway in type 2 diabetes and atherosclerosis: Friend or foe?
Published in Pharmacological research (01-11-2021)“…Type 2 diabetes and atherosclerosis have gradually garnered great attention as inflammatory diseases. Previously, the fact that Interleukin-1β (IL-1β)…”
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19
Role of prostaglandin E2 in macrophage polarization: Insights into atherosclerosis
Published in Biochemical pharmacology (01-01-2023)“…[Display omitted] Atherosclerosis, a trigger of cardiovascular disease, poses grave threats to human health. Although atherosclerosis depends on lipid…”
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20
15-Hydroxyprostaglandin dehydrogenase inhibitor SW033291 ameliorates hepatic abnormal lipid metabolism, ER stress, and inflammation through PGE2/EP4 in T2DM mice
Published in Bioorganic chemistry (01-08-2023)“…[Display omitted] •SW033291 improves aberrant hepatic lipid metabolism by inhibiting lipid uptake, lipogenesis and promoting fatty acid β-oxidation.•SW033291…”
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