Search Results - "Weighill, Deborah"
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Fungal-Bacterial Networks in the Populus Rhizobiome Are Impacted by Soil Properties and Host Genotype
Published in Frontiers in microbiology (29-03-2019)“…Plant root-associated microbial symbionts comprise the plant rhizobiome. These microbes function in provisioning nutrients and water to their hosts, impacting…”
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2
Linking crop traits to transcriptome differences in a progeny population of tetraploid potato
Published in BMC plant biology (18-03-2020)“…Potato is the third most consumed crop in the world. Breeding for traits such as yield, product quality and pathogen resistance are main priorities…”
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3-way networks: application of hypergraphs for modelling increased complexity in comparative genomics
Published in PLoS computational biology (01-03-2015)“…We present and develop the theory of 3-way networks, a type of hypergraph in which each edge models relationships between triplets of objects as opposed to…”
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Data Integration in Poplar: ‘Omics Layers and Integration Strategies
Published in Frontiers in genetics (25-09-2019)“…Populus trichocarpa is an important biofuel feedstock that has been the target of extensive research and is emerging as a model organism for plants, especially…”
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Defining the genetic components of callus formation: A GWAS approach
Published in PloS one (17-08-2018)“…A characteristic feature of plant cells is the ability to form callus from parenchyma cells in response to biotic and abiotic stimuli. Tissue culture…”
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Gene Targeting in Disease Networks
Published in Frontiers in genetics (23-04-2021)“…Profiling of whole transcriptomes has become a cornerstone of molecular biology and an invaluable tool for the characterization of clinical phenotypes and the…”
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7
Genus-Wide Assessment of Lignocellulose Utilization in the Extremely Thermophilic Genus Caldicellulosiruptor by Genomic, Pangenomic, and Metagenomic Analyses
Published in Applied and environmental microbiology (01-05-2018)“…Metagenomic data from Obsidian Pool (Yellowstone National Park, USA) and 13 genome sequences were used to reassess genus-wide biodiversity for the extremely…”
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Multi-Phenotype Association Decomposition: Unraveling Complex Gene-Phenotype Relationships
Published in Frontiers in genetics (10-05-2019)“…Various patterns of multi-phenotype associations (MPAs) exist in the results of Genome Wide Association Studies (GWAS) involving different topologies of single…”
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Characterization of DWARF14 Genes in Populus
Published in Scientific reports (15-02-2016)“…Strigolactones are a new class of plant hormones regulating shoot branching and symbiotic interactions with arbuscular mycorrhizal fungi. Studies of branching…”
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10
Network Metamodeling: Effect of Correlation Metric Choice on Phylogenomic and Transcriptomic Network Topology
Published in Advances in biochemical engineering, biotechnology (01-01-2017)“…We explore the use of a network meta-modeling approach to compare the effects of similarity metrics used to construct biological networks on the topology of…”
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Finding New Cell Wall Regulatory Genes in Populus trichocarpa Using Multiple Lines of Evidence
Published in Frontiers in plant science (08-10-2019)“…Understanding the regulatory network controlling cell wall biosynthesis is of great interest in Populus trichocarpa, both because of its status as a model…”
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12
Wavelet-Based Genomic Signal Processing for Centromere Identification and Hypothesis Generation
Published in Frontiers in genetics (31-05-2019)“…Various 'omics data types have been generated for , each providing a layer of information which can be represented as a density signal across a chromosome. We…”
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13
High Throughput Screening Technologies in Biomass Characterization
Published in Frontiers in energy research (27-11-2018)“…Biomass analysis is a slow and tedious process and not solely due to the long generation time for most plant species. Screening large numbers of plant variants…”
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Pleiotropic and Epistatic Network-Based Discovery: Integrated Networks for Target Gene Discovery
Published in Frontiers in energy research (11-05-2018)“…Biological organisms are complex systems that are composed of functional networks of interacting molecules and macro-molecules. Complex phenotypes are the…”
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Predicting genotype-specific gene regulatory networks
Published in Genome research (01-03-2022)“…Understanding how each person's unique genotype influences their individual patterns of gene regulation has the potential to improve our understanding of human…”
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Promise of bile circulating tumor DNA in biliary tract cancers
Published in Cancer (01-06-2023)“…An explosion of technological advances has facilitated the unprecedented use of liquid biopsy methods to isolate and interrogate circulating tumor DNA for…”
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GRAND: a database of gene regulatory network models across human conditions
Published in Nucleic acids research (07-01-2022)“…Abstract Gene regulation plays a fundamental role in shaping tissue identity, function, and response to perturbation. Regulatory processes are controlled by…”
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Parallel accelerated Custom Correlation Coefficient calculations for genomics applications
Published in Parallel computing (01-05-2019)“…•A novel mapping of 2-way and 3-way CCC calculations to GPUs is presented.•A parallel algorithm scaling to thousands of compute nodes is developed.•Near-ideal…”
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Parallel accelerated vector similarity calculations for genomics applications
Published in Parallel computing (01-07-2018)“…•A novel mapping of 2-way / 3-way vector similarity calculations to GPUs is presented.•A parallel algorithm scaling to thousands of compute nodes is…”
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DRAGON: Determining Regulatory Associations using Graphical models on multi-Omic Networks
Published in Nucleic acids research (22-02-2023)“…The increasing quantity of multi-omic data, such as methylomic and transcriptomic profiles collected on the same specimen or even on the same cell, provides a…”
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