Search Results - "Weigel, Thaddeus K"
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Chronic social defeat reduces myelination in the mouse medial prefrontal cortex
Published in Scientific reports (18-04-2017)“…The medial prefrontal cortex (mPFC) plays a key role in top-down control of the brain’s stress axis, and its structure and function are particularly vulnerable…”
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Cutting Edge: Critical Roles for Microbiota-Mediated Regulation of the Immune System in a Prenatal Immune Activation Model of Autism
Published in The Journal of immunology (1950) (01-08-2018)“…Recent studies suggest that autism is often associated with dysregulated immune responses and altered microbiota composition. This has led to growing…”
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Altered circadian behavior and light sensing in mouse models of Alzheimer's disease
Published in Frontiers in aging neuroscience (20-06-2023)“…Circadian symptoms have long been observed in Alzheimer's disease (AD) and often appear before cognitive symptoms, but the mechanisms underlying circadian…”
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The Behavioral Sequelae of Social Defeat Require Microglia and Are Driven by Oxidative Stress in Mice
Published in The Journal of neuroscience (10-07-2019)“…Chronic social defeat (CSD) in male mice can produce anxiety and aberrant socialization. Animals susceptible to CSD show activation of microglia, which have…”
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Decoding microglia responses to psychosocial stress reveals blood-brain barrier breakdown that may drive stress susceptibility
Published in Scientific reports (26-07-2018)“…An animal’s ability to cope with or succumb to deleterious effects of chronic psychological stress may be rooted in the brain’s immune responses manifested in…”
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Insulin resistance and impaired lipid metabolism as a potential link between diabetes and Alzheimer's disease
Published in Drug development research (01-04-2020)“…Diabetes disrupts organs throughout the body including the brain. Evidence suggests diabetes is a risk factor for Alzheimer's disease (AD) and…”
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Oxidized cholesterol species as signaling molecules in the brain: diabetes and Alzheimer's disease
Published in Health psychology & behavioral medicine (01-12-2019)“…Type 2 diabetes is associated with adverse central nervous system effects, including a doubled risk for Alzheimer's disease (AD) and increased risk of…”
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Critical roles for microbiota-mediated regulation of the immune system in a prenatal immune activation model of autism
Published in The Journal of immunology (1950) (02-07-2018)“…Recent studies suggest that autism is often associated with dysregulated immune responses and altered microbiota composition. This has led to growing…”
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