Search Results - "Weigel, Guenter"
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Electrospun polyurethane vascular grafts: In vitro mechanical behavior and endothelial adhesion molecule expression
Published in Journal of biomedical materials research. Part A (01-05-2010)“…Engineered small diameter vascular grafts must closely match mechanical characteristics of native vessels and exhibit stimulus‐responsive bioactivity. In this…”
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Heme oxygenase and angiogenic activity of endothelial cells: stimulation by carbon monoxide and inhibition by tin protoporphyrin-IX
Published in Antioxidants & redox signaling (01-04-2003)“…The activity of heme oxygenase enzymes (HOs) is responsible for the endogenous source of carbon monoxide (CO). Their activities can be inhibited by tin…”
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The decellularized porcine heart valve matrix in tissue engineering: platelet adhesion and activation
Published in Thrombosis and haemostasis (01-09-2005)“…An approach in tissue engineering of heart valves is the use of decellularized xenogeneic matrices to avoid immune response after implantation. The…”
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IgG deposition and activation of the classical complement pathway involvement in the activation of human granulocytes by decellularized porcine heart valve tissue
Published in Biomaterials (01-04-2008)“…Abstract Decellularization treatment of heart valves has been thought to eliminate tissue immunogenicity. Early failure of tissue-engineered xenogeneic heart…”
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Beck and back: A paradigm change in coronary sinus interventions—pulsatile stretch on intact coronary venous endothelium
Published in The Journal of thoracic and cardiovascular surgery (01-06-2007)“…Objectives Strategies to recover myocardium in therapeutically unresponsive patients are again under scrutiny, including techniques developed in the pioneering…”
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Decellularized, xenogeneic small-diameter arteries: Transition from a muscular to an elastic phenotype in vivo
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-10-2008)“…Reports regarding the biocompatibility of xenogeneic, decellularized bioprosthetic implants differ between bioinertness and complete graft degradation. We…”
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Opposite effects of prostaglandin-J2 on VEGF in normoxia and hypoxia: role of HIF-1
Published in Biochemical and biophysical research communications (30-01-2004)“…The vascular endothelial growth factor (VEGF) is produced in response to hypoxia or inflammatory cytokines. In normoxia VEGF synthesis is upregulated by…”
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Effect of mycophenolate mofetil therapy on lymphocyte activation in heart transplant recipients
Published in The Journal of heart and lung transplantation (01-10-2002)“…Mycophenolic acid is reported to provide effective immunosuppression by inhibiting inosine monophosphate dehydrogenase. In an attempt to monitor the effects of…”
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Extracorporeal Membrane Oxygenation Induces Short-Term Loss of High-Molecular-Weight von Willebrand Factor Multimers
Published in Anesthesia and analgesia (01-04-2015)“…BACKGROUND:High-molecular-weight (HMW) von Willebrand factor (vWF) multimers are crucial for primary hemostasis. Increased shear stress from ventricular assist…”
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(Meth)acrylate-based photoelastomers as tailored biomaterials for artificial vascular grafts
Published in Journal of polymer science. Part A, Polymer chemistry (15-05-2009)“…Cardiovascular disease is one of the leading causes of morbidity and mortality in the western hemisphere. Currently available synthetic vascular conduits, like…”
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Human immune-cell response towards diverse xenogeneic and allogeneic decellularized biomaterials
Published in International journal of surgery (London, England) (01-12-2016)“…Abstract Background Immunological knowledge on processed biological implants and mesh-prostheses is still mainly based on animal models, lacking information on…”
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Predicting Transfusion Requirements During Extracorporeal Membrane Oxygenation
Published in Journal of cardiothoracic and vascular anesthesia (01-06-2016)“…Patients requiring extracorporeal membrane oxygenation (ECMO) have a well-known bleeding risk and the potential for experiencing possibly fatal thromboembolic…”
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Anti-coagulation assessment with prothrombin time and anti-Xa assays in real-world patients on treatment with rivaroxaban
Published in Annals of hematology (01-09-2015)“…Monitoring of anti-coagulation with the direct factor Xa inhibitor rivaroxaban is considered unnecessary in a routine clinical setting. However, assessment of…”
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Identification of Aspergillus fumigatus Surface Components That Mediate Interaction of Conidia and Hyphae With Human Platelets
Published in The Journal of infectious diseases (01-10-2015)“…Background. Platelets were recently identified as a part of innate immunity. They are activated by contact with Aspergillus fumigatus; putative consequences…”
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Role of Heme Oxygenase-1 in Human Endothelial Cells: Lesson From the Promoter Allelic Variants
Published in Arteriosclerosis, thrombosis, and vascular biology (01-08-2010)“…OBJECTIVE—Heme oxygenase-1 (HO-1) is an antioxidative, antiinflammatory, and cytoprotective enzyme that is induced in response to cellular stress. The HO-1…”
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Decellularization protocols of porcine heart valves differ importantly in efficiency of cell removal and susceptibility of the matrix to recellularization with human vascular cells
Published in The Journal of thoracic and cardiovascular surgery (01-02-2004)“…We compared 3 different decellularization protocols in porcine heart valves for efficiency of complete cell removal and potential for recellularization…”
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Genotyping of coeliac-specific human leucocyte antigen in children with type 1 diabetes: does this screening method make sense?
Published in Archives of disease in childhood (01-07-2017)“…ObjectivesDue to a high linkage disequilibrium of diabetes and coeliac-specific human leucocyte antigen (HLA) genotypes, the prevalence of coeliac disease (CD)…”
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Interference of the new oral anticoagulant dabigatran with frequently used coagulation tests
Published in Clinical chemistry and laboratory medicine (01-09-2012)“…Dabigatran etexilate is a new oral anticoagulant for the therapy and prophylaxis of venous thromboembolism and stroke prevention in patients with atrial…”
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Electrospun Small-Diameter Polyurethane Vascular Grafts: Ingrowth and Differentiation of Vascular-Specific Host Cells
Published in Artificial organs (01-01-2012)“…No small‐diameter synthetic graft has yet shown comparable performance to autologous vessels. Synthetic conduits fail due to their inherent surface…”
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