Search Results - "Weigand, Luise U."

Formin-like 1 (FMNL1) Is Regulated by N-terminal Myristoylation and Induces Polarized Membrane Blebbing by Han, Yanyan, Eppinger, Elfriede, Schuster, Ingrid G., Weigand, Luise U., Liang, Xiaoling, Kremmer, Elisabeth, Peschel, Christian, Krackhardt, Angela M.

“…The formin protein formin-like 1 (FMNL1) is highly restrictedly expressed in hematopoietic lineage-derived cells and has been previously identified as a…”
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349 A novel ‘off the shelf’ TCR-NK cell therapy platform for the treatment of solid tumours: development of optimised MAGE-A4 targeting TCR-NK cells for advancement into the clinic by Cardoso, Ines, Pollmann, Sylvie, Weigand, Luise U

“…BackgroundT cell receptor (TCR)-T based therapies, such as MAGE-A4 TCR-T cells, have shown compelling data demonstrating effective infiltration into and…”
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A single TCR alpha-chain with dominant peptide recognition in the allorestricted HER2/neu-specific T cell repertoire by Liang, Xiaoling, Weigand, Luise U, Schuster, Ingrid G, Eppinger, Elfriede, van der Griendt, Judith C, Schub, Andrea, Leisegang, Matthias, Sommermeyer, Daniel, Anderl, Florian, Han, Yanyan, Ellwart, Joachim, Moosmann, Andreas, Busch, Dirk H, Uckert, Wolfgang, Peschel, Christian, Krackhardt, Angela M

“…T cells can recognize tumor cells specifically by their TCR and the transfer of TCR-engineered T cells is a promising novel tool in anticancer therapies. We…”
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Isolation of human MHC class II‐restricted T cell receptors from the autologous T‐cell repertoire with potent anti‐leukaemic reactivity by Weigand, Luise U, Liang, Xiaoling, Schmied, Sabine, Mall, Sabine, Klar, Richard, Stötzer, Oliver J, Salat, Christoph, Götze, Katharina, Mautner, Josef, Peschel, Christian, Krackhardt, Angela M

“…Summary Adoptive transfer of T cells genetically modified with tumour‐specific T‐cell receptors (TCR) is a promising novel approach in the treatment of cancer…”
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Abstract 1329: Development of the first optimised “off the shelf” MAGE-A4 targeting TCR-NK cells for advancement into the clinic for the treatment of solid tumors by Vollmers, Sarah, Cieslar-Pobuda, Artur, Kmiecik, Justyna, Malachin, Giulia, Sætersmoen, Michelle L., Haugen, Frida Høsøien, Boieri, Margherita, Sandve, Maja, Clement, Dennis, Cardoso, Ines, Wanichawan, Pimthanya, Haugstøyl, Martha E., Oldenburg, Anja, Christ, Liliane, Oberoi, Pranav, Mora-Velandia, Luz, Holm, Anders, Hassan, Namir J., Gauthy, Emilie, Ino, Julia, Pollmann, Sylvie, Weigand, Luise U.

“…Abstract T cell receptor (TCR)-T based therapies, such as MAGE-A4 TCR-T cells, have shown compelling data demonstrating effective infiltration into and…”
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An approved in vitro approach to preclinical safety and efficacy evaluation of engineered T cell receptor anti-CD3 bispecific by Harper, Jane, Adams, Katherine J, Bossi, Giovanna, Wright, Debbie E, Stacey, Andrea R, Bedke, Nicole, Martinez-Hague, Ruth, Blat, Dan, Humbert, Laure, Buchanan, Hazel, Le Provost, Gabrielle S, Donnellan, Zoe, Carreira, Ricardo J, Paston, Samantha J, Weigand, Luise U, Canestraro, Martina, Sanderson, Joseph P, Botta Gordon-Smith, Sophie, Lowe, Kate L, Rygiel, Karolina A, Powlesland, Alex S, Vuidepot, Annelise, Hassan, Namir J, Cameron, Brian J, Jakobsen, Bent K, Dukes, Joseph

“…Robust preclinical testing is essential to predict clinical safety and efficacy and provide data to determine safe dose for first-in-man studies. There are a…”
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Abstract 2805: Cancer-specific T cell receptor isolation for cancer immunotherapy by Weigand, Luise U., Paston, Samantha, Hibbert, Linda, Ryan, Ruth K., Baker, Debbie E., Simmons, Ruth A., Harper, Jane V., Dukes, Joseph D., Bossi, Giovanna, Grand, Francis, Hickman, Emma, Powlesland, Alex, Vuidepot, Annelise, Hassan, Namir J., Jakobsen, Bent K.

“…Abstract Malignant cells may be recognized by T cells binding cell surface Class I HLA-peptide complexes presenting disease-associated epitopes. Many cancer…”
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Transfer of Human T-Cell Receptors (TCR) Containing Murine Chimeric Constant Beta-Gamma-Chain Sequences Reduces the Risk of Mixed Heterodimers and Shows Enhanced in Vitro-Accumulation of TCR-Tranduced Effector Cells by Krackhardt, Angela, Liang, Xiaoling, Schuster, Ingrid G, Weigand, Luise U, Eppinger, Elfriede, Uckert, Wolfgang, Busch, Dirk, Peschel, Christian

“…Abstract 3583 Poster Board III-520 Adoptive transfer of T-cell receptor (TCR)-transduced T cells may represent an attractive and promising novel approach to…”
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A Single TCR{alpha}-Chain with Dominant Peptide Recognition in the Allorestricted HER2/neu-Specific T Cell Repertoire by Liang, Xiaoling, Weigand, Luise U, Schuster, Ingrid G, Eppinger, Elfriede, van der Griendt, Judith C, Schub, Andrea, Leisegang, Matthias, Sommermeyer, Daniel, Anderl, Florian, Han, Yanyan, Ellwart, Joachim, Moosmann, Andreas, Busch, Dirk H, Uckert, Wolfgang, Peschel, Christian, Krackhardt, Angela M

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