Search Results - "Weidner, Julie"
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Spotlight on microRNAs in allergy and asthma
Published in Allergy (Copenhagen) (01-06-2021)“…In past 10 years, microRNAs (miRNAs) have gained scientific attention due to their importance in the pathophysiology of allergic diseases and their potential…”
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Circulating microRNAs correlate to clinical parameters in individuals with allergic and non-allergic asthma
Published in Respiratory research (07-05-2020)“…Asthma is a chronic airway disease affecting millions of people. Better methods to define asthma subgroups using clinical parameters and molecular biomarkers…”
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Context-dependent deposition and regulation of mRNAs in P-bodies
Published in eLife (03-01-2018)“…Cells respond to stress by remodeling their transcriptome through transcription and degradation. Xrn1p-dependent degradation in P-bodies is the most prevalent…”
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Editorial: The application of new technology in the diagnosis of allergic diseases
Published in Frontiers in allergy (25-09-2024)Get full text
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House Dust Mite Induces Bone Marrow IL-33-Responsive ILC2s and TH Cells
Published in International journal of molecular sciences (26-05-2020)“…Type 2 innate lymphoid cells (ILC2s) and their adaptive counterpart type 2 T helper (TH2) cells respond to interleukin-33 (IL-33) by producing IL-5, which is a…”
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Interplay Between the IL-33/ST2 Axis and Bone Marrow ILC2s in Protease Allergen-Induced IL-5-Dependent Eosinophilia
Published in Frontiers in immunology (02-06-2020)“…Eosinophils develop from CD34 progenitor cells in the bone marrow under the influence of interleukin (IL)-5. Several cell types produce IL-5, including type 2…”
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Rapamycin Dampens Inflammatory Properties of Bone Marrow ILC2s in IL-33-Induced Eosinophilic Airway Inflammation
Published in Frontiers in immunology (03-06-2022)“…The alarmin cytokine interleukin (IL)-33 plays an important proinflammatory role in type 2 immunity and can act on type 2 innate lymphoid cells (ILC2s) and…”
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Defects in the secretory pathway and high Ca2+ induce multiple P-bodies
Published in Molecular biology of the cell (01-08-2010)“…mRNA is sequestered and turned over in cytoplasmic processing bodies (PBs), which are induced by various cellular stresses. Unexpectedly, in Saccharomyces…”
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Gymnotic uptake of AntimiRs alter microRNA-34a levels in 2D and 3D epithelial cell culture
Published in Molecular therapy. Nucleic acids (12-09-2023)“…MicroRNAs are attractive therapeutic targets in many diseases, including chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. Among…”
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The Serum/Glucocorticoid-Regulated Kinase 1 Is Targeted by miR-19a in CD4+ T Cells
Published in Cells (Basel, Switzerland) (01-01-2023)“…The polarization of CD4+ T cells into different T helper subsets is an important process in many diseases, including asthma. Part of the adaptive immune…”
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Correction: Context-dependent deposition and regulation of mRNAs in P-bodies
Published in eLife (23-08-2018)Get full text
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Single-nucleotide polymorphisms in the sulfatase-modifying factor 1 gene are associated with lung function and COPD
Published in ERJ open research (01-04-2022)“…Single nucleotide polymorphisms (SNPs) in various genes have been shown to associate with COPD, suggesting a role in disease pathogenesis. Sulfatase modifying…”
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Preparation of Sequencing RNA Libraries through Chemical Cross-linking Coupled to Affinity Purification (cCLAP) in Saccharomyces cerevisiae
Published in Bio-protocol (05-10-2018)“…Ribonucleoprotein particles (mRNPs) are complexes consisting of mRNAs and RNA-binding proteins (RBPs) which control mRNA transcription localization, turnover,…”
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Biomarker-based clustering of patients with chronic obstructive pulmonary disease
Published in ERJ open research (01-01-2023)“…COPD has been associated repeatedly with single biomarkers of systemic inflammation, ignoring the complexity of inflammatory pathways. This study aimed to…”
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Sulfatase modifying factor 1 (SUMF1) is associated with Chronic Obstructive Pulmonary Disease
Published in Respiratory research (02-05-2017)“…It has been observed that mice lacking the sulfatase modifying factor (Sumf1) developed an emphysema-like phenotype. However, it is unknown if SUMF1 may play a…”
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MicroRNAs in type 2 immunity
Published in Cancer letters (01-07-2018)“…Type 2 immunity drives the pathology of allergic diseases and is necessary for expulsion of parasitic worms as well as having important implications in tumor…”
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Chemical modification patterns for microRNA therapeutic mimics: a structure-activity relationship (SAR) case-study on miR-200c
Published in Nucleic acids research (12-04-2024)“…Abstract microRNA (miRNA) mimics are an emerging class of oligonucleotide therapeutics, with a few compounds already in clinical stages. Synthetic miRNAs are…”
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House Dust Mite Induces Bone Marrow IL-33-Responsive ILC2s and T H Cells
Published in International journal of molecular sciences (26-05-2020)“…Type 2 innate lymphoid cells (ILC2s) and their adaptive counterpart type 2 T helper (T 2) cells respond to interleukin-33 (IL-33) by producing IL-5, which is a…”
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Physiological estrogen levels are dispensable for the sex difference in immune responses during allergen-induced airway inflammation
Published in Immunobiology (1979) (01-05-2023)“…Women show an increased prevalence of adult-onset asthma compared to men and previous studies have shown that testosterone inhibits while estrogen worsens…”
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The polysome-associated proteins Scp160 and Bfr1 prevent P body formation under normal growth conditions
Published in Journal of cell science (01-05-2014)“…Numerous mRNAs are degraded in processing bodies (P bodies) in Saccharomyces cerevisiae. In logarithmically growing cells, only 0-1 P bodies per cell are…”
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