Search Results - "Weick, James"

Improved outcomes with "7+3" induction chemotherapy for acute myeloid leukemia over the past four decades: analysis of SWOG trial data by Othus, Megan, Garcia-Manero, Guillermo, Godwin, John E, Weick, James K, Appelbaum, Frederick R, Erba, Harry P, Estey, Elihu H

“…We have previously shown that complete response (CR) rates and overall survival of patients with acute myeloid leukemia have improved since the 1980s. However,…”
Get full text

Associations between complete remission and 2- to 3-year survival following 7 + 3 induction for acute myeloid leukemia by Othus, Megan, Garcia-Manero, Guillermo, Godwin, John, Weick, James, Stirewalt, Derek, Appelbaum, Frederick, Erba, Harry, Estey, Elihu

“…Among acute myeloid leukemia (AML) patients treated with 7 + 3 induction, we evaluate the association between complete morphologic remission (CR) and long-term…”
Get full text

Second cycle remission achievement with 7+3 and survival in adults with newly diagnosed acute myeloid leukemia: analysis of recent SWOG trials by Othus, Megan, Estey, Elihu H., Garcia-Manero, Guillermo, Wood, Brent L., Stirewalt, Derek L., Godwin, John E., Weick, James K., Anderson, Jeanne E., Appelbaum, Frederick R., Erba, Harry P., Walter, Roland B.

Get full text

Prognostic significance of Bcl-6 protein expression in DLBCL treated with CHOP or R-CHOP: a prospective correlative study by Winter, Jane N., Weller, Edie A., Horning, Sandra J., Krajewska, Maryla, Variakojis, Daina, Habermann, Thomas M., Fisher, Richard I., Kurtin, Paul J., Macon, William R., Chhanabhai, Mukesh, Felgar, Raymond E., Hsi, Eric D., Medeiros, L. Jeffrey, Weick, James K., Reed, John C., Gascoyne, Randy D.

“…Bcl-6 protein expression, a marker of germinal center origin, has been associated with a favorable prognosis in diffuse large B-cell lymphoma (DLBCL). To…”
Get full text

Expression of p21 protein predicts clinical outcome in DLBCL patients older than 60 years treated with R-CHOP but not CHOP: a prospective ECOG and Southwest Oncology Group correlative study on E4494 by Winter, Jane N, Li, Shuli, Aurora, Vikas, Variakojis, Daina, Nelson, Beverly, Krajewska, Maryla, Zhang, Lijun, Habermann, Thomas M, Fisher, Richard I, Macon, William R, Chhanabhai, Mukesh, Felgar, Raymond E, Hsi, Eric D, Medeiros, L Jeffrey, Weick, James K, Weller, Edie A, Melnick, Ari, Reed, John C, Horning, Sandra J, Gascoyne, Randy D

“…To prospectively investigate the prognostic significance of p21 and p53 expression in diffuse large B-cell lymphoma in the context of the U.S. Intergroup trial…”
Get full text

Increasing Lengths of First Complete Remission with 7+3 Induction Chemotherapy for Acute Myeloid Leukemia over the Past Four Decades: Analysis of SWOG Trial Data by Othus, Megan, Garcia-Manero, Guillermo, Godwin, John E., Weick, James K., Appelbaum, Frederick R., Erba, Harry P., Estey, Elihu H.

“…Background: We have previously shown that the survival of patients with AML who fail to achieve complete remission (CR) with 7+3 has improved since the 1980s…”
Get full text

The evaluation of gemcitabine in resistant or relapsing multiple myeloma, phase II: a Southwest Oncology Group study by WEICK, James K, CROWLEY, John J, HUSSEIN, Mohamed A, MOORE, Dennis F, BARLOGIE, Bart

“…Gemcitabine is a cytosine arabinoside (Ara-C) analog with activity in many human tumor systems. We evaluated the drug's activity in resistant or relapsing…”
Get full text

Estrogen Receptor Methylation Is Associated with Improved Survival in Adult Acute Myeloid Leukemia by QING LI, KOPECKY, K. J, MOHAN, A, WILLMAN, C. L, APPELBAUM, F. R, WEICK, J. K, ISSA, J.-P. J

“…Estrogen receptor methylation (ERM) is a frequent molecular alteration in adult acute myeloid leukemia (AML). In this study, we sought to determine the…”
Get full text

Associations between Complete Remissions (CRs) with 7+3 Induction Chemotherapy for Acute Myeloid Leukemia and 2-3 Year Survival (“Potential Cure”) over the Past Four Decades: Analysis of SWOG Trial Data by Othus, Megan, Garcia-Manero, Guillermo, Godwin, John, Weick, James K., Anderson, Jeanne E., Stirewalt, Derek, Appelbaum, Frederick R., Erba, Harry P., Estey, Elihu H.

“…Background: CRs are known to be associated with improved overall survival (OS) for acute myeloid leukemia (AML) patients (pts) treated with curative-intent,…”
Get full text

2nd cycle Remission Achievement with 7+3 Is Associated with Shorter Survival in Adults with Newly Diagnosed Acute Myeloid Leukemia: Analysis of Recent SWOG Trials by Othus, Megan, Estey, Elihu H., Garcia-Manero, Guillermo, Wood, Brent, Stirewalt, Derek, Godwin, John, Weick, James K., Anderson, Jeanne E., Appelbaum, Frederick R., Erba, Harry P., Walter, Roland B.

“…Background: Intensive chemotherapy will induce a complete morphologic remission (CR) in many adults with acute myeloid leukemia (AML). Whether it matters that…”
Get full text

Frequency and Clinical Significance of the Expression of the Multidrug Resistance Proteins MDR1/P-Glycoprotein, MRP1, and LRP in Acute Myeloid Leukemia. A Southwest Oncology Group Study by Leith, Catherine P., Kopecky, Kenneth J., Chen, I-Ming, Eijdems, Lisette, Slovak, Marilyn L., McConnell, Thomas S., Head, David R., Weick, James, Grever, Michael R., Appelbaum, Frederick R., Willman, Cheryl L.

“…Therapeutic resistance is a major obstacle in the treatment of acute myeloid leukemia (AML). Such resistance has been associated with rapid drug efflux…”
Get full text

Differences in Outcomes in Males and Females with Diffuse Large B-Cell Lymphoma with Induction Rituximab and Follicular Lymphoma Treated with Maintenance Rituximab by Habermann, Thomas M, Hong, Fangxin, Morrison, Vicki A., Dakhil, Shaker R., Weick, James K., Frankel, Stanley R., Gascoyne, Randy D., Fisher, Richard I, Cheson, Bruce D., Weller, Edie A., Kahl, Brad S., Peterson, Bruce A., Hochster, Howard S, Horning, Sandra J.

“…Abstract 3705 Improved outcomes were reported in USA studies in DLBCL (Habermann et al. J Clin Oncol 2006) in a two-staged randomized study of R-CHOP…”
Get full text

Gene Risk Scores Based on Expression of 6 Genes Quanitated by Nuclease Protection Assay in Formalin Fixed Paraffin-Embedded Tissue (FFPET) Specimens From CHOP and RCHOP Treated Patients with Diffuse Large B-Cell Lymphoma (DLBCL) Predict Outcome: An ECOG and SWOG Study by Winter, Jane N., Hong, Fangxin, Rimsza, Lisa M., LeBlanc, Michael, Variakojis, Daina, Krajewska, Maryla, Habermann, Thomas M., Melnick, Ari, Weick, James K., Pollock, Frederick, Botros, Ihab, Reed, John C., Fisher, Richard I, Kahl, Brad S., Horning, Sandra J., Gascoyne, Randy D.

“…Abstract 87 The International Prognostic Index (IPI) remains the most powerful predictor of clinical outcome in DLBCL in the R-CHOP era, serving as a useful…”
Get full text

A Randomized Investigation of High-Dose Versus Standard-Dose Cytosine Arabinoside With Daunorubicin in Patients With Previously Untreated Acute Myeloid Leukemia: A Southwest Oncology Group Study by Weick, James K., Kopecky, Kenneth J., Appelbaum, Frederick R., Head, David R., Kingsbury, Laura L., Balcerzak, Stanley P., Bickers, John N., Hynes, H.E., Welborn, Jeanna L., Simon, Sheryl R., Grever, Michael

“…Interest in high-dose cytarabine (HDAC) for both induction and postremission therapy for acute myeloid leukemia (AMD prompted the Southwest Oncology Group…”
Get full text

Massive hemolysis in Clostridium perfringens infections by Becker, R C, Giuliani, M, Savage, R A, Weick, J K

“…Over a 14-month period at the Cleveland Clinic Foundation, 424 strains of Clostridium were isolated; of these, 52 strains were Clostridium perfringens isolated…”
Get more information

Alternating Combination Chemotherapy and Levamisole Improves Survival in Multiple Myeloma : A Southwest Oncology Group Study by SALMON, Sydney E, HAUT, Arthur, BONNET, John D, AMARE, Mammo, WEICK, James K, DURIE, Brian G. M, DIXON, Dennis O

Get full text

Expression of p21 Protein Predicts Clinical Outcome in DLBCL Patients Over Age 60 Treated with R-CHOP but not CHOP: A prospective ECOG and SWOG correlative study of E4494 by Winter, Jane N., Li, Shuli, Aurora, Vikas, Variakojis, Daina, Nelson, Beverly, Krajewska, Maryla, Zhang, Lijun, Habermann, Thomas M., Fisher, Richard I., Macon, William R., Chhanabhai, Mukesh, Felgar, Raymond E., Hsi, Eric D., Medeiros, L. Jeffrey, Weick, James K., Weller, Edie A., Melnick, Ari, Reed, John C., Horning, Sandra J., Gascoyne, Randy D.

Get full text

Correlation of Multidrug Resistance (MDR1) Protein Expression With Functional Dye/Drug Efflux in Acute Myeloid Leukemia by Multiparameter Flow Cytometry: Identification of Discordant MDR-/Efflux+ and MDR1+/Efflux- Cases by Leith, Catherine P., Chen, L-Ming, Kopecky, Kenneth J., Appelbaum, Frederick R., Head, David R., Godwin, John E., Weick, James K., Willman, Cheryl L.

“…Resistance to chemotherapy is a major factor limiting successful treatment of acute myeloid leukemia (AMD; one of the best characterized drug resistance…”
Get full text

Prognostic significance of Bcl-6 protein expression in DLBCL treated with chop or R-CHOP : a prospective correlative study. Commentary by MOSKOWITZ, Craig, WINTER, Jane N, CHHANABHAI, Mukesh, FELGAR, Raymond E, HSI, Eric D, MEDEIROS, L. Jeffrey, WEICK, James K, REED, John C, GASCOYNE, Randy D, WELLER, Edie A, HORNING, Sandra J, KRAJEWSKA, Maryla, VARIAKOJIS, Daina, HABERMANN, Thomas M, FISHER, Richard I, KURTIN, Paul J, MACON, William R

Get full text

The use of cimetidine for the treatment of pruritus in polycythemia vera by Weick, J K, Donovan, P B, Najean, Y, Dresch, C, Pisciotta, A V, Cooperberg, A A, Goldberg, J D

“…Thirty-four patients with polycythemia vera complicated by pruritus were treated with 900 mg of cimetidine daily for 30 days and their responses to treatment…”
Get more information