Search Results - "Wei-Chih Chen"

Dipeptidylpeptidase 4 as a Marker of Activated Fibroblasts and a Potential Target for the Treatment of Fibrosis in Systemic Sclerosis by Soare, Alina, Györfi, Hermina A., Matei, Alexandru E., Dees, Clara, Rauber, Simon, Wohlfahrt, Thomas, Chen, Chih‐Wei, Ludolph, Ingo, Horch, Raymund E., Bäuerle, Tobias, Hörsten, Stephan, Mihai, Carina, Distler, Oliver, Ramming, Andreas, Schett, Georg, Distler, Jörg H. W.

“…Objective Expression of dipeptidylpeptidase 4 (DPP‐4) identifies a dermal fibroblast lineage involved in scarring during wound healing. The role of DDP‐4 in…”
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Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis by Chakraborty, Debomita, Šumová, Barbora, Mallano, Tatjana, Chen, Chih-Wei, Distler, Alfiya, Bergmann, Christina, Ludolph, Ingo, Horch, Raymund E., Gelse, Kolja, Ramming, Andreas, Distler, Oliver, Schett, Georg, Šenolt, Ladislav, Distler, Jörg H. W.

“…Signal transducer and activator of transcription 3 (STAT3) is phosphorylated by various kinases, several of which have been implicated in aberrant fibroblast…”
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Nintedanib inhibits macrophage activation and ameliorates vascular and fibrotic manifestations in the Fra2 mouse model of systemic sclerosis by Huang, Jingang, Maier, Christiane, Zhang, Yun, Soare, Alina, Dees, Clara, Beyer, Christian, Harre, Ulrike, Chen, Chih-Wei, Distler, Oliver, Schett, Georg, Wollin, Lutz, Distler, Jörg H W

“…Nintedanib is an inhibitor targeting platelet-derived growth factor receptor, fibroblast growth factor receptor and vascular endothelial growth factor receptor…”
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Response to ‘Validation of generalized drug‐related rash diagnoses using International Classification of Diseases 9th and 10th Revision codes’ by Chen, Chih‐Wei, Wei, James Cheng‐Chung

“…Linked Article: Goldenberg et al. Br J Dermatol 2022; 186:583–585…”
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A Low-Power Dual-Frequency SIMO Buck Converter Topology With Fully-Integrated Outputs and Fast Dynamic Operation in 45 nm CMOS by Chih-Wei Chen, Fayed, Ayman

“…The dual-frequency single-inductor multiple-output (DF-SIMO) buck converter topology is proposed. Unlike conventional single-frequency SIMO topologies, the…”
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Airway obstruction as a pulmonary manifestation of rheumatoid arthritis: comment on the article by Prisco et al by Wang, Sheng‐Yuan, Chen, Chih‐Wei, Wei, James Cheng‐Chung

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Near-infrared nanosecond-pulsed laser-activated highly efficient intracellular delivery mediated by nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles by Santra, Tuhin Subhra, Kar, Srabani, Chen, Te-Chang, Chen, Chih-Wei, Borana, Jayant, Lee, Ming-Chang, Tseng, Fan-Gang

“…Here, an efficient intracellular delivery of molecules with high cell viability is reported using nanosecond-pulsed laser-activated plasmonic photoporation,…”
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Regarding: Adherence to a healthy sleep pattern is associated with lower risks of all‐cause, cardiovascular, and cancer‐specific mortality by Lin, Yen‐Po, Chen, Chih‐Wei, Wei, James Cheng‐Chung

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Inactivation of autophagy ameliorates glucocorticoid-induced and ovariectomy-induced bone loss by Lin, Neng-Yu, Chen, Chih-Wei, Kagwiria, Rosebeth, Liang, Ruifang, Beyer, Christian, Distler, Alfiya, Luther, Julia, Engelke, Klaus, Schett, Georg, Distler, Jörg Hw

“…Autophagy has recently been shown to regulate osteoclast activity and osteoclast differentiation. Here, we aim to investigate the impact of autophagy…”
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A platform‐based approach to assisting rheumatoid arthritis management by Walter, Paul, Kau, Chien‐Kai, Chen, Chih‐Wei

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Recombinant Adenosine Deaminase Ameliorates Inflammation, Vascular Disease, and Fibrosis in Preclinical Models of Systemic Sclerosis by Zhang, Yun, Zhu, Honglin, Layritz, Florian, Luo, Hui, Wohlfahrt, Thomas, Chen, Chih‐Wei, Soare, Alina, Bergmann, Christina, Ramming, Andreas, Groeber, Florian, Reuter, Christian, Fornasini, GianFranco, Soukhareva, Nadejda, Schreiber, Brian, Ramamurthy, Santosh, Amann, Kerstin, Schett, Georg, Distler, Jörg H. W.

“…Objective Systemic sclerosis (SSc) is characterized by fibrosis, vascular disease, and inflammation. Adenosine signaling plays a central role in fibroblast…”
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Critical care response during the COVID-19 pandemic by Chen, Wei-Chih, Yang, Kuang-Yao

“…Since the coronavirus disease 2019 (COVID-19) pandemic, millions of people worldwide have passed away due to critical illness. Intensive care for severe…”
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Hypoxia-preconditioned mesenchymal stem cells ameliorate ischemia/reperfusion-induced lung injury by Liu, Yung-Yang, Chiang, Chi-Huei, Hung, Shih-Chieh, Chian, Chih-Feng, Tsai, Chen-Liang, Chen, Wei-Chih, Zhang, Haibo

“…Hypoxia preconditioning has been proven to be an effective method to enhance the therapeutic action of mesenchymal stem cells (MSCs). However, the beneficial…”
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Evidence for a strain-tuned topological phase transition in ZrTe5 by Mutch, Joshua, Chen, Wei-Chih, Went, Preston, Qian, Tiema, Wilson, Ilham Zaky, Andreev, Anton, Chen, Cheng-Chien, Chu, Jiun-Haw

“…A phase transition between topologically distinct insulating phases involves closing and reopening the bandgap. Near the topological phase transition, the bulk…”
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The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis by Zehender, Ariella, Huang, Jingang, Györfi, Andrea-Hermina, Matei, Alexandru-Emil, Trinh-Minh, Thuong, Xu, Xiaohan, Li, Yi-Nan, Chen, Chih-Wei, Lin, Jianping, Dees, Clara, Beyer, Christian, Gelse, Kolja, Zhang, Zhong-Yin, Bergmann, Christina, Ramming, Andreas, Birchmeier, Walter, Distler, Oliver, Schett, Georg, Distler, Jörg H. W.

“…Uncontrolled activation of TGFβ signaling is a common denominator of fibrotic tissue remodeling. Here we characterize the tyrosine phosphatase SHP2 as a…”
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TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy by Zehender, Ariella, Li, Yi-Nan, Lin, Neng-Yu, Stefanica, Adrian, Nüchel, Julian, Chen, Chih-Wei, Hsu, Hsiao-Han, Zhu, Honglin, Ding, Xiao, Huang, Jingang, Shen, Lichong, Györfi, Andrea-Hermina, Soare, Alina, Rauber, Simon, Bergmann, Christina, Ramming, Andreas, Plomann, Markus, Eckes, Beate, Schett, Georg, Distler, Jörg H. W.

“…Activation of fibroblasts is essential for physiological tissue repair. Uncontrolled activation of fibroblasts, however, may lead to tissue fibrosis with organ…”
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3D printed hydrogel scaffolds combining glutathione depletion-induced ferroptosis and photothermia-augmented chemodynamic therapy for efficiently inhibiting postoperative tumor recurrence by Dang, Wentao, Chen, Wei-Chih, Ju, Enguo, Xu, Yanteng, Li, Kai, Wang, Haixia, Wang, Kun, Lv, Shixian, Shao, Dan, Tao, Yu, Li, Mingqiang

“…Surgical resection to achieve tumor-free margins represents a difficult clinical scenario for patients with hepatocellular carcinoma. While post-surgical…”
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Using Magnetic Micelles Combined with Carbon Fiber Ionization Mass Spectrometry for the Screening of Trace Triazine Herbicides from Aqueous Samples by Chen, Chih-Wei, Yang, Tzu-Ling, Chen, Yu-Chie

“…Triazine herbicides are commonly used in agriculture to eliminate weeds. However, they can persist in the environment. In this study, we explored a new method…”
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Characterization of TAG‐63 and its role on axonal transport in C. elegans by Bhan, Prerana, Muthaiyan Shanmugam, Muniesh, Wang, Ding, Bayansan, Odvogmed, Chen, Chih‐Wei, Wagner, Oliver I.

“…Model organisms are increasingly used to study and understand how neurofilament (NF)‐based neurological diseases develop. However, whether a NF homolog exists…”
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NME3 Regulates Mitochondria to Reduce ROS-Mediated Genome Instability by Chen, Chih-Wei, Tsao, Ning, Zhang, Wei, Chang, Zee-Fen

“…NME3 is a member of the nucleoside diphosphate kinase (NDPK) family that binds to the mitochondrial outer membrane to stimulate mitochondrial fusion. In this…”
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