Search Results - "Wei, Zaiwa"
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1
Icaritin greatly attenuates β‐amyloid‐induced toxicity in vivo
Published in CNS neuroscience & therapeutics (01-04-2024)“…Aims The accumulation and deposition of β‐amyloid (Aβ) has always been considered a major pathological feature of Alzheimer's disease (AD). The latest and…”
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A label-free and rapid fluorometric strategy for microRNA detection using CRISPR-Cas12a coupled with copper nanoparticles
Published in Mikrochimica acta (1966) (01-07-2024)“…CRISPR-Cas12a with robust trans-cleavage activity were employed to mitigate background fluorescence signal, achieving sensitive detection of miRNA-21. The…”
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Identification and validation of potential diagnostic signature and immune cell infiltration for NAFLD based on cuproptosis-related genes by bioinformatics analysis and machine learning
Published in Frontiers in immunology (26-09-2023)“…Background and aims Cuproptosis has been identified as a key player in the development of several diseases. In this study, we investigate the potential role of…”
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Identification of diagnostic markers and molecular clusters of cuproptosis-related genes in alcohol-related liver disease based on machine learning and experimental validation
Published in Heliyon (30-09-2024)“…Alcohol-related liver disease (ALD) is a worldwide burden. Cuproptosis has been shown to play a key role in the development of several diseases. However, the…”
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5
RBCK1 overexpression is associated with immune cell infiltration and poor prognosis in hepatocellular carcinoma
Published in Aging (Albany, NY.) (11-01-2024)“…RBCK1 is an important E3 ubiquitin ligase, which plays an important role in many major diseases. However, the function and mechanism of RBCK1 in pan-cancer and…”
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Mitochondrial dysfunction and NDUFS3: Insights from a PINK1B9 Drosophila model in Parkinson’s disease pathogenesis
Published in Neuroscience letters (14-09-2024)“…PTEN-induced kinase1 (PINK1) mutation is the main cause of autosomal recessive inheritance and early-onset Parkinson’s disease. Mitochondrial respiratory chain…”
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7
Vitamin K2 protects against Aβ42-induced neurotoxicity by activating autophagy and improving mitochondrial function in Drosophila
Published in Neuroreport (07-04-2021)“…Alzheimer disease is characterized by progressive decline in cognitive function due to neurodegeneration induced by accumulation of Aβ and hyperphosphorylated…”
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8
Withaferin A alleviates traumatic brain injury induced secondary brain injury via suppressing apoptosis in endothelia cells and modulating activation in the microglia
Published in European journal of pharmacology (05-05-2020)“…Traumatic brain injury (TBI) is a major public health concern with high rates of morbidity and mortality worldwide. Currently used medications, though…”
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Overexpressed PERK suppresses the neurodegenerative phenotypes in PINK1B9 flies by enhancing mitochondrial function
Published in Neurochemistry international (01-11-2020)“…PTEN-induced putative kinase 1 (PINK1) mutation induces autosomal recessive Parkinson's Disease (PD), mitochondrial dysfunction is the central pathogenic…”
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10
Over Expression of PERK Suppresses the Neurodegenerative Phenotypes in PINK1 Mutant Flies by Enhancing Mitochondrial Function (P5.8-004)
Published in Neurology (09-04-2019)“…Abstract only…”
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11
Mitochondrial dysfunction and NDUFS3: Insights from a PINK1 B9 Drosophila model in Parkinson's disease pathogenesis
Published in Neuroscience letters (03-08-2024)“…PTEN-induced kinase1 (PINK1) mutation is the main cause of autosomal recessive inheritance and early-onset Parkinson's disease. Mitochondrial respiratory chain…”
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