Search Results - "Wei, Yujiao"

Spatiotemporal Variations in Drought and Vegetation Response in Inner Mongolia from 1982 to 2019 by Wei, Yujiao, Zhu, Lin, Chen, Yun, Cao, Xinyu, Yu, Huilin

“…Drought events cause ecological problems, including reduced water resources and degraded vegetation. Quantifying vegetation responses to drought is essential…”
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Unveiling the explanatory power of environmental variables in soil organic carbon mapping: A global–local analysis framework by Wei, Yujiao, Chen, Yiyun, Wang, Jiaxue, Wang, Bo, Yu, Peiheng, Hong, Yongsheng, Zhu, Liandong

“…[Display omitted] •A framework to assess the environmental variables’ explanatory power was proposed.•The relationship between environmental variables and SOC…”
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On the effectiveness of multi-scale landscape metrics in soil organic carbon mapping by Wang, Jiaxue, Chen, Yiyun, Wu, Zihao, Wei, Yujiao, Zhang, Zheyue, Wang, Xiaomi, Huang, Jingyi, Shi, Zhou

“…•Environmental variables surrounding sample locations play an important role in DSM.•Landscape metrics can comprehensively characterize the surrounding…”
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First orally bioavailable prodrug of proteolysis targeting chimera (PROTAC) degrades cyclin-dependent kinases 2/4/6 in vivo by Wei, Mingming, Zhao, Rui, Cao, Yuting, Wei, Yujiao, Li, Ming, Dong, Zhiqiang, Liu, Yulin, Ruan, Hao, Li, Ying, Cao, Sheng, Tang, Zhiwen, Zhou, Yuanyuan, Song, Wei, Wang, Yubo, Wang, Jiefu, Yang, Guang, Yang, Cheng

“…A growing number of reports suggested that the inhibitor targeting cyclin-dependent kinases (CDK) 2/4/6 can act as a more feasible chemotherapy strategy. In…”
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Unraveling the threshold and interaction effects of environmental variables on soil organic carbon mapping in plateau watershed by Zhang, Chi, Chen, Yiyun, Wei, Yujiao, Yu, Peiheng, Hong, Yongsheng, Hu, Yazhen, Wang, Jiaxue, Shi, Zhou

“…[Display omitted] •Landscape metrics were used as environmental variables to estimate and map SOC.•Environmental variables have threshold and interaction…”
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The 50% effective dose of hydromorphone and morphine for epidural analgesia in the hemorrhoidectomy: a double-blind, sequential dose-finding study by Cao, Xianghua, Gui, Qiangjun, Wei, Yujiao, Lan, Lanhui, Xiao, Huiling, Wen, Shihong, Li, Xueping

“…Although previous studies have showed that epidural morphine can be used as a complement to local anesthetics for analgesia after postcesarean delivery under…”
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Synthesis and Discovery Novel Anti-Cancer Stem Cells Compounds Derived from the Natural Triterpenoic Acids by Liu, Xinhua, Li, Benlong, Zhang, Zhen, Wei, Yujiao, Xu, Zhongxin, Qin, Shuanglin, Liu, Ning, Zhao, Rui, Peng, Junya, Yang, Guang, Qi, Min, Liu, Tongtong, Xie, Maodun, Liu, Shuangwei, Gao, Xian, Lu, Cheng, Zhu, Lijun, Long, Xinyu, Kang, Hong, Sun, Tao, Zhou, Honggang, Wei, Mingming, Yang, Guang, Yang, Cheng

“…Cancer stem cells (CSCs) have been reported to be involved in tumorigenesis, tumor recurrence, cancer invasion, metastasis, and drug-resistance. Therefore, the…”
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Optimal Mapping of Soil Erodibility in a Plateau Lake Watershed: Empirical Models Empowered by Machine Learning by Wang, Jiaxue, Yujiao Wei, Sun, Zheng, Gu, Shixiang, Bai, Shihan, Chen, Jinming, Chen, Jing, Hong, Yongsheng, Chen, Yiyun

“…Soil erodibility (K) refers to the inherent ability of soil to withstand erosion. Accurate estimation and spatial prediction of K values are vital for…”
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One-step hydrothermal method synthesized pH-dependent carbon dots for multistage anti-counterfeiting by Mao, Xiang, Zhao, Xia, Hu, Hao, Li, Zequan, Xiong, Wei, Wei, Yujiao, Gao, Wei

“…[Display omitted] •Color-changing fluorescent CDs with pH dependence were prepared by using cheap and environmentally friendly raw materials.•The CDs have high…”
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Discovery of novel and bioavailable histone deacetylases and cyclin-dependent kinases dual inhibitor to impair the stemness of leukemia cells by Liu, Yulin, Wei, Yujiao, Wang, Xuan, Ma, Lan, Li, Xuechun, Sun, Yue, Wu, Yanjie, Zhang, Li, Wang, Jiefu, Li, Ming, Zhang, Kun, Wei, Mingming, Yang, Guang, Yang, Cheng

“…Acute myeloid leukemia (AML) has been confirmed as one of the most lethal heterogeneous clonal diseases. In addition to being essential for the development and…”
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Design and synthesis of novel Flavone-based histone deacetylase inhibitors antagonizing activation of STAT3 in breast cancer by Wei, Mingming, Xie, Maodun, Zhang, Zhen, Wei, Yujiao, Zhang, Juan, Pan, Hongli, Li, Benlong, Wang, Jingjing, Song, Yang, Chong, Chuangke, Zhao, Rui, Wang, Jiefu, Yu, Li, Yang, Guang, Yang, Cheng

“…Histone deacetylases (HDACs) inhibitors have demonstrated a great clinical achievement in hematological malignancies. However, the efficacy of HDACs inhibitors…”
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Design and discovery of new selective and potent VEGF receptor 2 tyrosine kinase inhibitors by Hou, Fei, Yao, Yuhong, Wei, Yujiao, Wang, Yubo, Cao, Yangzi, Liu, Xinqiang, Zheng, Liting, Zhang, Qingqing, Jiao, Yue, Chen, Yukun, Meng, Yue, Sun, Yue, Wu, Yanjie, Wang, Jiefu, Wang, Junfeng, Wu, Zhou, Zhang, Kun, Wei, Mingming, Yang, Guang

“…[Display omitted] A series of novel substituted 4-anilinoquinazolines and their related compounds were designed and prepared by 3D modeling as potential…”
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Structure optimization and discovery of novel compound for the treatment of insertion mutations within exon 20 of EGFR and HER2 by Cui, Yetong, Wang, Ruonan, Wei, Yujiao, Hou, Fei, Li, Haixi, Jiang, Yurui, Sun, Yue, Fu, Shushu, Zuo, Lina, Wang, Xiaoji, Li, Ming, Li, Jinling, Liu, Ning, Zhang, Kun, Wei, Mingming, Yang, Guang

“…[Display omitted] •25 novel Afatinib-Poziotinib hybrids were designed via 3D modeling of kinase structure.•Compound 56 could inhibit the growth of tumor cells…”
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Discovery and Optimization of a Novel 2H‑Pyrazolo[3,4-d]pyrimidine Derivative as a Potent Irreversible Pan-Fibroblast Growth Factor Receptor Inhibitor by Wei, Yujiao, Tang, Yanting, Zhou, Yunyun, Yang, Yuyu, Cui, Yetong, Wang, Xuan, Wang, Yubo, Liu, Yulin, Liu, Ning, Wang, Qianqian, Li, Chong, Ruan, Hao, Zhou, Honggang, Wei, Mingming, Yang, Guang, Yang, Cheng

“…Fibroblast growth factor receptors (FGFRs) have become promising therapeutic targets in various types of cancers. In fact, several selective irreversible…”
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Discovery and Optimization of a Novel 2 H -Pyrazolo[3,4-d]pyrimidine Derivative as a Potent Irreversible Pan-Fibroblast Growth Factor Receptor Inhibitor by Wei, Yujiao, Tang, Yanting, Zhou, Yunyun, Yang, Yuyu, Cui, Yetong, Wang, Xuan, Wang, Yubo, Liu, Yulin, Liu, Ning, Wang, Qianqian, Li, Chong, Ruan, Hao, Zhou, Honggang, Wei, Mingming, Yang, Guang, Yang, Cheng

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5α-Epoxyalantolactone Inhibits Metastasis of Triple-Negative Breast Cancer Cells by Covalently Binding a Conserved Cysteine of Annexin A2 by Wei, Mingming, Zhou, Yunyun, Li, Chong, Yang, Yuyu, Liu, Tongtong, Liu, Yulin, Wei, Yujiao, Liu, Ning, Liu, Shuangwei, Wang, Qianqian, Cao, Sheng, Sun, Yue, Sheng, Pengzhen, Lu, Cheng, Yang, Cheng, Liu, Xiang, Yang, Guang

“…Triple-negative breast cancer (TNBC) has been considered the most aggressive and mortal breast cancer. Thus far, it remains an important challenge to develop…”
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Detection of trinitrotoluene based on fluorescence quenching sensor technology by Zhang, Meijuan, Fang, Huiwen, Wei, Yujiao, Yang, Jinhong, Wang, Weihua, He, Shengnan

“…At present, more and more attention has been paid to the detection of common explosives trinitrotoluene（TNT）. In this study, a low-cost fluorene-based…”
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Design and synthesis of Leukotriene A4 hydrolase inhibitors to alleviate idiopathic pulmonary fibrosis and acute lung injury by Li, Xiaohe, Xie, Maodun, Lu, Cheng, Mao, Jiahe, Cao, Yuting, Yang, Yuyu, Wei, Yujiao, Liu, Xinhua, Cao, Sheng, Song, Yang, Peng, Junya, Zhou, Yunyun, Jiang, Qiuyan, Lin, Gang, Qin, Shuanglin, Qi, Min, Hou, Min, Liu, Xiang, Zhou, Honggang, Yang, Guang, Yang, Cheng

“…Idiopathic pulmonary fibrosis (IPF) and acute lung injury (ALI) are considered two severe public health issues, attributed to malfunctions of neutrophils. They…”
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Synthesis and discovery of a drug candidate for treatment of idiopathic pulmonary fibrosis through inhibition of TGF-β1 pathway by Li, Xiaohe, Lu, Cheng, Liu, Shuangwei, shuaishuai Liu, Su, Chengcheng, Xiao, Ting, Bi, Zhun, Sheng, Pengzhen, Huang, Mengying, Liu, Xinhua, Wei, Yujiao, Zhao, Lin, Miao, Shengxiang, Mao, Jiahe, Huang, Kai, Gao, Shaoyan, Liu, Ning, Qi, Min, Liu, Tongtong, Qin, Shuanglin, Wei, Luqing, Sun, Tao, Ning, Wen, Yang, Guang, Zhou, Honggang, Yang, Cheng

“…In this study, anti-IPF lead compounds 42 and 44, derived from natural sesquiterpene lactones Isoalantolactone and alantolactone, were discovered by screening…”
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Corrigendum to ‘Synthesis and discovery of a drug candidate for treatment of idiopathic pulmonary fibrosis through inhibition of TGF-b1 pathway’ [Eur. J. Med. Chem. 157 (2018) 229–247] by Li, Xiaohe, Lu, Cheng, Liu, Shuangwei, Liu, Shuaishuai, Su, Chengcheng, Xiao, Ting, Bi, Zhun, Sheng, Pengzhen, Huang, Mengying, Liu, Xinhua, Wei, Yujiao, Zhao, Lin, Miao, Shengxiang, Mao, Jiahe, Huang, Kai, Gao, Shaoyan, Liu, Ning, Qi, Min, Liu, Tongtong, Qin, Shuanglin, Wei, Luqing, Sun, Tao, Ning, Wen, Yang, Guang, Zhou, Honggang, Yang, Cheng

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