Search Results - "Wei, Wenshi"

Role of Fto on CaMKII/CREB signaling pathway of hippocampus in depressive-like behaviors induced by chronic restraint stress mice by Shen, Jun, Yang, Lu, Wei, Wenshi

“…•Chronic restraint stress leads to depressive-like behaviors and destruction of synaptic plasticity.•CaMKII/CREB signaling pathway regulates synaptic proteins…”
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CSF GAP-43 as a biomarker of synaptic dysfunction is associated with tau pathology in Alzheimer’s disease by Qiang, Qiang, Skudder-Hill, Loren, Toyota, Tomoko, Wei, Wenshi, Adachi, Hiroaki

“…To test whether cerebrospinal fluid (CSF) growth-associated protein 43 (GAP-43) concentration is elevated in Alzheimer’s disease (AD) dementia and its…”
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Exosomes Derived From M2 Microglia Cells Attenuates Neuronal Impairment and Mitochondrial Dysfunction in Alzheimer's Disease Through the PINK1/Parkin Pathway by Li, Nan, Shu, Jun, Yang, Xiaoyan, Wei, Wenshi, Yan, Aijuan

“…The accumulation of abnormal aggregation of amyloid-β plaques is one of the most distinguishing pathologies of Alzheimer's disease (AD) and is highly toxic to…”
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Identification of programmed cell death-related gene signature and associated regulatory axis in cerebral ischemia/reperfusion injury by Shu, Jun, Yang, Lu, Wei, Wenshi, Zhang, Li

“…Background: Numerous studies have suggested that programmed cell death (PCD) pathways play vital roles in cerebral ischemia/reperfusion (I/R) injury. However,…”
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Characterizing the distributions of IDO-1 expressing macrophages/microglia in human and murine brains and evaluating the immunological and physiological roles of IDO-1 in RAW264.7/BV-2 cells by Ji, Rong, Ma, Lixiang, Chen, Xinyu, Sun, Renqiang, Zhang, Li, Saiyin, Hexige, Wei, Wenshi

“…Indoleamine 2,3-dioxygenase 1 (IDO-1) is an immunosuppressive enzyme expressed in the placenta, neoplastic cells, and macrophages to reject T cells by…”
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Classification of EEG signals using a multiple kernel learning support vector machine by Li, Xiaoou, Chen, Xun, Yan, Yuning, Wei, Wenshi, Wang, Z Jane

“…In this study, a multiple kernel learning support vector machine algorithm is proposed for the identification of EEG signals including mental and cognitive…”
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Identification of Molecular Signatures and Candidate Drugs in Vascular Dementia by Bioinformatics Analyses by Shu, Jun, Wei, Wenshi, Zhang, Li

“…Vascular dementia (VaD) is considered to be the second most common form of dementia after Alzheimer's disease, and no specific drugs have been approved for VaD…”
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Neuroprotective Mechanisms of Glucagon-Like Peptide-1-Based Therapies in Ischemic Stroke: An Update Based on Preclinical Research by Yang, Xiaoyan, Qiang, Qiang, Li, Nan, Feng, Peng, Wei, Wenshi, Hölscher, Christian

“…The public and social health burdens of ischemic stroke have been increasing worldwide. Hyperglycemia leads to a greater risk of stroke. This increased risk is…”
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Association of Pre-stroke Frailty With Prognosis of Elderly Patients With Acute Cerebral Infarction: A Cohort Study by Yang, Fuxia, Li, Nan, Yang, Lu, Chang, Jie, Yan, Aijuan, Wei, Wenshi

“…BackgroundFrailty is a state of cumulative degradation of physiological functions that leads to adverse outcomes such as disability or mortality. Currently,…”
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Establishment of an induced pluripotent stem cell (SIAISi016-A) line from a 62-years old Chinese Han patient with Alzheimer's disease by Huang, Juan, Wang, Ying, Zhao, Jian, Deng, Yulei, Wei, Wenshi

“…A 62-years old Alzheimer's disease (AD) male patient donated his Peripheral blood mononuclear cells. The non-integrating episomal vector system used to…”
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Association between Twenty-Four-Hour Ambulatory Blood Pressure Variability and Cerebral Small Vessel Disease Burden in Acute Ischemic Stroke by Shen, Jun, Yang, Lu, Xu, Ziwei, Wei, Wenshi

“…Objective. This study is aimed at investigating the association between the twenty-four-hour ambulatory blood pressure variability monitoring (ABPM) and…”
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Personalized Biomarkers and Neuropsychological Status Can Predict Post-Stroke Fatigue by Zhang, Hanwen, Liu, Guidong, Zhang, Li, Wei, Wenshi

“…Post-stroke fatigue (PSF) is a common complication of stroke that has a negative impact on prognosis and recovery. We aimed to investigate the relationship…”
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Deep Brain Stimulation: A Potential Treatment for Dementia in Alzheimer's Disease (AD) and Parkinson's Disease Dementia (PDD) by Lv, Qing, Du, Ailian, Wei, Wenshi, Li, Yuanyuan, Liu, Gailing, Wang, Xiao Ping

“…Damage to memory circuits may lead to dementia symptoms in Alzheimer's disease (AD) and Parkinson's disease dementia (PDD). Recently, deep brain stimulation…”
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White matter hyperintensity mediating gait disorders in iNPH patients via neurofilament light chain by Yang, Lu, Yang, Fuxia, Deng, Yao, Yan, Aijuan, Wei, Wenshi, Fang, Xuhao

“…This study aimed to analyze the differences in regional white matter hyperintensities (WMH) volume and cerebrospinal fluid biomarker levels between idiopathic…”
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Identification of potential drug targets for vascular dementia and carotid plaques by analyzing underlying molecular signatures shared by them by Shu, Jun, Ren, Yiqing, Tan, Wen, Wei, Wenshi, Zhang, Li, Chang, Jie

“…Background: Vascular dementia (VaD) and carotid atherosclerotic plaques are common in the elderly population, conferring a heavy burden on families and…”
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Aberrant Topological Patterns of Structural Covariance Networks in Cognitively Normal Elderly Adults With Mild Behavioral Impairment by Shu, Jun, Qiang, Qiang, Yan, Yuning, Ren, Yiqing, Wei, Wenshi, Zhang, Li

“…Mild behavioral impairment (MBI), characterized by the late-life onset of sustained and meaningful neuropsychiatric symptoms, is increasingly recognized as a…”
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A patient of isolated myelopathy secondary to papillary thyroid carcinoma with excellent response to surgical resection by Xu, Ziwei, Ren, Yiqing, Shen, Jun, Zhao, Dehao, Wei, Wenshi

“…•Paraneoplastic myelopathy (PM) only accounts for 6.5% of the total PNS, most commonly caused by lung and breast carcinoma, while thyroid carcinoma is an…”
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ANCA-associated hypertrophic spinal pachymeningitis presenting with longitudinally extensive transverse myelitis: A case report by Shu, Jun, Gu, Chunhui, Ren, Yiqing, Wei, Wenshi

“…The man first visited other hospital; there were no characteristic findings about magnetic resonance image (MRI) of his head, but MRI of spine showed…”
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Nocturnal Sleep Problems Mediate the Impact on Quality of Life of Early Morning Off in Parkinson's Disease by Zhang, Yu, Zhang, Zi en, Shi, De, Zhao, Yi, Huang, Lihong, Zhao, Yanxin, Wang, Hui, Zhao, Jing, Wang, Feng, Zhao, Chaorong, Gao, Shan, Wei, Wenshi, Huang, Dongya, Liu, Zhen guo

“…Background: Early morning off (EMO) refers to off-states in the morning in people diagnosed with Parkinson's disease (PwPD). This study determined the clinical…”
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Dl-3-n-butylphthalide prevents chronic restraint stress-induced depression-like behaviors and cognitive impairment via regulating CaMKII/CREB/BDNF signaling pathway in hippocampus by Shen, Jun, Yang, Lu, Wei, Wenshi

“…BACKGROUNDStress is not scarce in peoples' daily life that may result in mental diseases and cognitive impairments. Chronic restraint stress (CRS) is a…”
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