Search Results - "Wei, Weijia"
-
1
Real-time imaging and tracking of ultrastable organic dye nanoparticles in living cells
Published in Biomaterials (01-07-2016)“…Abstract Semiconductor quantum dots and upconversion nanoparticles have been broadly used for live cell imaging due to their color tunability and…”
Get full text
Journal Article -
2
Multiplexed Promoter Engineering for Improving Thaxtomin A Production in Heterologous Streptomyces Hosts
Published in Life (Basel, Switzerland) (06-05-2022)“…Thaxtomin A is a potent bioherbicide in both organic and conventional agriculture; however, its low yield hinders its wide application. Here, we report the…”
Get full text
Journal Article -
3
CRISPR-Based Genetic Switches and Other Complex Circuits: Research and Application
Published in Life (Basel, Switzerland) (17-11-2021)“…CRISPR-based enzymes have offered a unique capability to the design of genetic switches, with advantages in designability, modularity and orthogonality…”
Get full text
Journal Article -
4
Novel switchable ECF sigma factor transcription system for improving thaxtomin A production in Streptomyces
Published in Synthetic and systems biotechnology (01-09-2022)“…The application of the valuable natural product thaxtomin A, a potent bioherbicide from the potato scab pathogenic Streptomyces strains, has been greatly…”
Get full text
Journal Article -
5
Smart doxorubicin nanoparticles with high drug payload for enhanced chemotherapy against drug resistance and cancer diagnosis
Published in Nanoscale (19-03-2015)“…Considering the obvious advantages in efficacy and price, doxorubicin (DOX) has been widely used for a range of cancers, which is usually encapsulated in…”
Get more information
Journal Article -
6
pH and redox dual responsive carrier-free anticancer drug nanoparticles for targeted delivery and synergistic therapy
Published in Nanomedicine (01-08-2019)“…Advanced drug delivery systems often employ nanomaterials as carriers to deliver drugs to desirable disease sites for enhanced efficacy. However, most systems…”
Get full text
Journal Article -
7
Synthetic robust perfect adaptation achieved by negative feedback coupling with linear weak positive feedback
Published in Nucleic acids research (28-02-2022)“…Abstract Unlike their natural counterparts, synthetic genetic circuits are usually fragile in the face of environmental perturbations and genetic mutations…”
Get full text
Journal Article -
8
A tight cold-inducible switch built by coupling thermosensitive transcriptional and proteolytic regulatory parts
Published in Nucleic acids research (02-12-2019)“…Abstract Natural organisms have evolved intricate regulatory mechanisms that sense and respond to fluctuating environmental temperatures in a heat- or…”
Get full text
Journal Article -
9
Smart surface coating of drug nanoparticles with cross-linkable polyethylene glycol for bio-responsive and highly efficient drug delivery
Published in Nanoscale (21-04-2016)“…Many drug molecules can be directly used as nanomedicine without the requirement of any inorganic or organic carriers such as silica and liposome…”
Get more information
Journal Article -
10
Paired Design of dCas9 as a Systematic Platform for the Detection of Featured Nucleic Acid Sequences in Pathogenic Strains
Published in ACS synthetic biology (17-02-2017)“…We developed an in vitro DNA detection system using a pair of dCas9 proteins linked to split halves of luciferase. Luminescence was induced upon colocalization…”
Get full text
Journal Article -
11
Construction and heterologous expression of the di-AFN A1 biosynthetic gene cluster in Streptomyces model strains
Published in Chinese journal of natural medicines (01-11-2022)“…Natural cyclohexapeptide AFN A1 fromStreptomyces alboflavus 313 has moderate antibacterial and antitumor activities. An artificial designed AFN A1 homodimer,…”
Get full text
Journal Article -
12
House Price Prediction Based on a Machine Learning Model
Published in 2021 2nd International Seminar on Artificial Intelligence, Networking and Information Technology (AINIT) (01-10-2021)“…Using the prediction on the dataset, the three authors modelled and predicted the Iowa house price dataset using support vector machines, random forests, and…”
Get full text
Conference Proceeding -
13
Up-regulation of breast cancer resistance protein plays a role in HER2-mediated chemoresistance through PI3K/Akt and nuclear factor-kappa B signaling pathways in MCF7 breast cancer cells
Published in Acta biochimica et biophysica Sinica (01-08-2011)“…Human epidermal growth factor receptor 2 (HER2/neu, also known as ErbB2) overexpression is correlated with the poor prognosis and chemoresistance in cancer…”
Get full text
Journal Article -
14
Connectivity in finite ad-hoc networks
Published in Science China. Information sciences (01-04-2008)“…Research on ad-hoc network connectivity has mainly focused on asymptotic results in the number of nodes in the network. For a one-dimensional ad-hoc network…”
Get full text
Journal Article