Search Results - "Wei, Tong‐You Wade"
-
1
Nonhydrolyzable Heptose Bis‐ and Monophosphate Analogues Modulate Pro‐inflammatory TIFA‐NF‐κB Signaling
Published in Chembiochem : a European journal of chemical biology (15-10-2020)“…d‐Glycero‐d‐manno‐heptose‐1β,7‐bisphosphate (HBP) and d‐glycero‐d‐manno‐heptose‐1β‐phosphate (H1P) are bacterial metabolites that were recently shown to…”
Get full text
Journal Article -
2
Binding and Enhanced Binding between Key Immunity Proteins TRAF6 and TIFA
Published in Chembiochem : a European journal of chemical biology (18-01-2019)“…Human tumor necrosis factor receptor associated factor (TRAF)‐interacting protein, with a forkhead‐associated domain (TIFA), is a key regulator of NF‐κB…”
Get full text
Journal Article -
3
The JMJD6/HURP axis promotes cell migration via NF‐κB‐dependent centrosome repositioning and Cdc42‐mediated Golgi repositioning
Published in Journal of cellular physiology (01-12-2022)“…Golgi apparatus (GA) and centrosome reposition toward cell leading end during directional cell migration in a coupling way, thereby determining cell polarity…”
Get full text
Journal Article -
4
The PRMT5/HURP axis retards Golgi repositioning by stabilizing acetyl‐tubulin and Golgi apparatus during cell migration
Published in Journal of cellular physiology (01-01-2022)“…The Golgi apparatus (GA) translocates to the cell leading end during directional migration, thereby determining cell polarity and transporting essential…”
Get full text
Journal Article -
5
TIFA protein expression is associated with pulmonary arterial hypertension
Published in Scientific reports (08-07-2021)“…Tumor necrosis factor receptor-associated factor-interacting protein with a forkhead-associated domain (TIFA), a key regulator of inflammation, may be involved…”
Get full text
Journal Article -
6
The crescent-like Golgi ribbon is shaped by the Ajuba/PRMT5/Aurora-A complex-modified HURP
Published in Cell communication and signaling (27-06-2023)“…Golgi apparatus (GA) is assembled as a crescent-like ribbon in mammalian cells under immunofluorescence microscope without knowing the shaping mechanisms. It…”
Get full text
Journal Article -
7
Glycosylation‐dependent interaction between CD69 and S100A8/S100A9 complex is required for regulatory T‐cell differentiation
Published in The FASEB journal (01-12-2015)“…ABSTRACT Cluster of differentiation (CD) 69 is a leukocyte activation receptor involved in the maintenance of immune homeostasis and is positively selected in…”
Get full text
Journal Article -
8
Aurora A and NF-κB Survival Pathway Drive Chemoresistance in Acute Myeloid Leukemia via the TRAF-Interacting Protein TIFA
Published in Cancer research (Chicago, Ill.) (15-01-2017)“…Aurora A-dependent NF-κB signaling portends poor prognosis in acute myeloid leukemia (AML) and other cancers, but the functional basis underlying this…”
Get full text
Journal Article -
9
Intermolecular Binding between TIFA-FHA and TIFA-pT Mediates Tumor Necrosis Factor Alpha Stimulation and NF-κB Activation
Published in Molecular and Cellular Biology (01-07-2012)“…Erratum ( vol. 32 , p. 3800 ) Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious…”
Get full text
Journal Article -
10
The mitosis-regulating and protein-protein interaction activities of astrin are controlled by aurora-A-induced phosphorylation
Published in American Journal of Physiology: Cell Physiology (01-09-2014)“…Cells display dramatic morphological changes in mitosis, where numerous factors form regulatory networks to orchestrate the complicated process, resulting in…”
Get more information
Journal Article -
11
Endothelium-specific SIRT7 targeting ameliorates pulmonary hypertension through Krüpple-like factor 4 deacetylation
Published in Cardiovascular research (30-03-2024)“…Abstract Aims Pulmonary hypertension (PH) is a pulmonary vascular disease characterized by a high mortality rate. Pulmonary arterial endothelium cells (PAECs)…”
Get full text
Journal Article -
12
Synthesis of a biotinylated heptose 1,7-bisphosphate analogue, a probe to study immunity and inflammation
Published in Organic & biomolecular chemistry (09-06-2021)“…d-glycero-d-manno-Heptose-1β,7-bisphosphate (HBP) is a bacterial metabolite that can induce a TIFA-dependent innate immune response in mammals. It was recently…”
Get more information
Journal Article -
13
The novel protein suppressed in lung cancer down-regulated in lung cancer tissues retards cell proliferation and inhibits the oncokinase Aurora-A
Published in Journal of thoracic oncology (01-06-2011)“…In an attempt to search for genes with abnormal expression in cancers, Suppressed in Lung Cancer (SLAN, also known as KIAA0256) is found underexpressed in…”
Get more information
Journal Article -
14
Epitranscriptomic Modification of MicroRNA Increases Atherosclerosis Susceptibility
Published in Circulation (New York, N.Y.) (28-11-2023)Get full text
Journal Article -
15
TIFA as a crucial mediator for NLRP3 inflammasome
Published in Proceedings of the National Academy of Sciences - PNAS (27-12-2016)“…Toll-like receptor-mediated NF-κB activation is a major innate immune reaction of vascular endothelial cells (ECs) in response to prooxidative and…”
Get full text
Journal Article -
16
Cover Image, Volume 237, Number 1, January 2022
Published in Journal of cellular physiology (01-01-2022)“…Inside Back Cover: The cover image is based on the Research Article The PRMT5/HURP axis retards Golgi repositioning by stabilizing acetyl‐tubulin and Golgi…”
Get full text
Journal Article -
17
Protein Arginine Methyltransferase 8: Tetrameric Structure and Protein Substrate Specificity
Published in Biochemistry (Easton) (29-12-2015)“…Type I protein arginine methyltransferases (PRMTs) catalyze asymmetric dimethylation of various proteins, and their dysregulations often correlate with…”
Get full text
Journal Article -
18
Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses
Published in Biochemistry (Easton) (13-10-2015)“…Forkhead-associated (FHA) domain is the only signaling domain that recognizes phosphothreonine (pThr) specifically. TRAF-interacting protein with an FHA domain…”
Get full text
Journal Article -
19
Overexpression of Aurora-A bypasses cytokinesis through phosphorylation of suppressed in lung cancer
Published in American Journal of Physiology: Cell Physiology (01-09-2019)“…Mitosis is a complicated process by which eukaryotic cells segregate duplicated genomes into two daughter cells. To achieve the goal, numerous regulators have…”
Get more information
Journal Article -
20
Methylosome protein 50 promotes androgen- and estrogen-independent tumorigenesis
Published in Cellular signalling (01-12-2014)“…Methylosome protein 50 (MEP50) is a component of methylosome where MEP50 binds protein substrates and activates the oncogenic protein arginine methyl…”
Get full text
Journal Article