Search Results - "Wei, Ruohan"
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KpsS1 Mediates the Glycosylation of Pseudaminic Acid in Acinetobacter Baumannii
Published in Chemistry : a European journal (19-07-2024)“…Pseudaminic acid (Pse) is found in the polysaccharide structures of the cell surface of various Gram‐negative pathogenic bacteria including Acinetobacter…”
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De novo synthesis of novel bacterial monosaccharide fusaminic acid
Published in Journal of antibiotics (01-06-2019)“…Fusobacterium nucleatum is an oral bacteria related to various types of diseases. As Gram-negative bacteria, lipopolysaccharide (LPS) of Fusobacterium…”
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3
Revealing the extracellular function of HMGB1 N-terminal region acetylation assisted by a protein semi-synthesis approach
Published in Chemical science (Cambridge) (27-09-2023)“…HMGB1 (high-mobility group box 1) is a non-histone chromatin-associated protein that has been widely reported as a representative damage-associated molecular…”
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4
Construction of diverse peptide structural architectures via chemoselective peptide ligation
Published in Chemical science (Cambridge) (13-04-2021)“…Herein, we report the development of a facile synthetic strategy for constructing diverse peptide structural architectures chemoselective peptide ligation. The…”
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Synthetic Pseudaminic-Acid-Based Antibacterial Vaccine Confers Effective Protection against Acinetobacter baumannii Infection
Published in ACS central science (22-09-2021)“…Acinetobacter baumannii exhibits resistance to most first-line antibiotics; thus, development of new antibacterial agents is urgently required. Pseudaminic…”
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Discovery of a Monoclonal Antibody That Targets Cell-Surface Pseudaminic Acid of Acinetobacter baumannii with Direct Bactericidal Effect
Published in ACS central science (28-02-2024)“…The therapeutic effects of antibodies include neutralization of pathogens, activation of the host complement system, and facilitation of phagocytosis of…”
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Total Synthesis of Pseudomonas aeruginosa 1244 Pilin Glycan via de Novo Synthesis of Pseudaminic Acid
Published in Journal of the American Chemical Society (27-09-2017)“…Pseudaminic acid (Pse) is a nonulosonic acid unique to bacterial species, found as a component of important cell surface glycans and glycoproteins in various…”
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8
LncRNA FOXCUT Stimulates the Progression of Endometrial Cancer
Published in Critical reviews in eukaryotic gene expression (2021)“…Endometrial cancer (EC) is a common gynecological tumor and the third leading cause of cancer-related death in women. Previous research has proved that long…”
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A Solution to Chemical Pseudaminylation via a Bimodal Glycosyl Donor for Highly Stereocontrolled α- and β‑Glycosylation
Published in Organic letters (17-05-2019)“…A robust methodology for the stereocontrolled chemical glycosylation of pseudaminic acid has been developed to afford both α- (axial) and β- (equatorial)…”
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10
Critical Reviews in Eukaryotic Gene Expression
Published in Critical reviews in eukaryotic gene expression (2021)“…Endometrial cancer (EC) is a common gynecological tumor and the third leading cause of cancer-related death in women. Previous research has proved that long…”
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11
Metabolic Labeling of Pseudaminic Acid-Containing Glycans on Bacterial Surfaces
Published in ACS chemical biology (19-10-2018)“…The rise in antibiotic-resistant bacteria is causing worldwide concerns. The urgent need for new antibacterial drugs calls for new thinking and strategies to…”
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12
Construction of diverse peptide structural architectures chemoselective peptide ligation
Published in Chemical science (Cambridge) (26-05-2021)“…Herein, we report the development of a facile synthetic strategy for constructing diverse peptide structural architectures via chemoselective peptide ligation…”
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