Search Results - "Wei, Robert G."

Reversible, orally available ADP receptor (P2Y12) antagonists Part I: Hit to lead process by Islam, Imadul, Yuan, Shendong, Wei, Robert G., Xu, Wei, Morrissey, Michael, Mohan, Raju, Zheng, Dewan, DiMella, Andrea, Dunning, Laura, Snider, Michael, Subramanyam, Babu, Tseng, Jih-Lie, Bryant, Judi A., Buckman, Brad O.

“…[Display omitted] •A hit to lead process to discover reversible, orally available ADP receptor (P2Y12) antagonists has been described.•Parallel synthesis,…”
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Design, Synthesis, and Activity of 2-Imidazol-1-ylpyrimidine Derived Inducible Nitric Oxide Synthase Dimerization Inhibitors by Davey, David D, Adler, Marc, Arnaiz, Damian, Eagen, Keith, Erickson, Shawn, Guilford, William, Kenrick, Margaret, Morrissey, Michael M, Ohlmeyer, Mike, Pan, Gonghua, Paradkar, Vidyadhar M, Parkinson, John, Polokoff, Mark, Saionz, Kurt, Santos, Cecile, Subramanyam, Babu, Vergona, Ron, Wei, Robert G, Whitlow, Marc, Ye, Bin, Zhao, Zuchun (Spring), Devlin, James J, Phillips, Gary

“…By the screening of a combinatorial library for inhibitors of nitric oxide (NO) formation by the inducible isoform of nitric oxide synthase (iNOS) using a…”
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CCR5 receptor antagonists: Discovery and SAR study of guanylhydrazone derivatives by Wei, Robert G., Arnaiz, Damian O., Chou, Yuo-Ling, Davey, Dave, Dunning, Laura, Lee, Wheeseong, Lu, Shou-Fu, Onuffer, James, Ye, Bin, Phillips, Gary

“…High throughput screening (HTS) led to the identification of the guanylhydrazone of 2-(4-chlorobenzyloxy)-5-bromobenzaldehyde as a CCR5 receptor antagonist…”
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CCR5 receptor antagonists: Discovery and SAR of novel 4-hydroxypiperidine derivatives by Lu, Shou-Fu, Chen, Binglong, Davey, Dave, Dunning, Laura, Jaroch, Stefan, May, Karen, Onuffer, James, Phillips, Gary, Subramanyam, Babu, Tseng, Jih-Lie, Wei, Robert G., Wei, Ming, Ye, Bin

“…Optimizing the guanylhydrazone of 2-(4-chlorobenzyloxy)-5-bromobenzaldehyde, which is a hit from high-throughput screening (HTS), let to discover the potent…”
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Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase by BIN YE, BAUMAN, John, MAY, Karen, MENDOZA, Lisa, PHILLIPS, Gary, SELCHAU, Victor, SCHLYER, Sabine, TSENG, Jih-Lie, WEI, Robert G, HONG YE, PARKINSON, John, GUILFORD, William J, MING CHEN, DAVEY, David, KHIM, Seock-Kyu, KING, Beverly, KIRKLAND, Thomas, KOCHANNY, Monica, LIANG, Amy, LENTZ, Dao

“…The synthesis and biological evaluation of a series of N-alkyl glycine amide analogs as LTA(4)-h inhibitors and the importance of the introduction of a benzoic…”
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Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors by KHIM, Seock-Kyu, BAUMAN, John, PHILLIPS, Gary, TSENG, Jih-Lie, WEI, Robert G, HONG YE, LIMEI YU, PARKINSON, John, GUILFORD, William J, EVANS, Jarred, FREEMAN, Beverly, KING, Beverly, KIRKLAND, Thomas, KOCHANNY, Monica, LENTZ, Dao, LIANG, Amy, MENDOZA, Lisa

“…The synthesis and biological evaluation of a series of aryl diamines as inhibitors of LTA(4)-h inhibitors are described. The optimization which led to the…”
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1-(1,3-Benzodioxol-5-ylmethyl)-3-[4-(1 H-imidazol-1-yl)phenoxy]-piperidine analogs as potent and selective inhibitors of nitric oxide formation by Wei, Robert G., Adler, Marc, Davey, David, Ho, Elena, Mohan, Raju, Polokoff, Mark, Tseng, Jih-Lie, Whitlow, Marc, Xu, Wei, Yuan, Shendong, Phillips, Gary

“…A new series of 1-(1,3-benzodioxol-5-ylmethyl)-3-[4-(1 H-Imidazol-1-yl)phenoxy]- piperidine analogs were discovered as potent and selective inhibitors of NO…”
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Discovery of novel and potent aryl diamines as leukotriene A sub(4) hydrolase inhibitors by Khim, Seock-Kyu, Bauman, John, Evans, Jarred, Freeman, Beverly, King, Beverly, Kirkland, Thomas, Kochanny, Monica, Lentz, Dao, Liang, Amy, Mendoza, Lisa, Phillips, Gary, Tseng, Jih-Lie, Wei, Robert G, Ye, Hong, Yu, Limei, Parkinson, John, Guilford, William J

“…The synthesis and biological evaluation of a series of aryl diamines as inhibitors of LTA sub(4)-h inhibitors are described. The optimization which led to the…”
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Discovery of novel and potent aryl diamines as leukotriene A 4 hydrolase inhibitors by Khim, Seock-Kyu, Bauman, John, Evans, Jarred, Freeman, Beverly, King, Beverly, Kirkland, Thomas, Kochanny, Monica, Lentz, Dao, Liang, Amy, Mendoza, Lisa, Phillips, Gary, Tseng, Jih-Lie, Wei, Robert G., Ye, Hong, Yu, Limei, Parkinson, John, Guilford, William J.

“…The synthesis and biological evaluation of a series of aryl diamines as inhibitors of LTA 4-h inhibitors are described. The optimization which led to the…”
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Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A sub(4) hydrolase by Ye, Bin, Bauman, John, Chen, Ming, Davey, David, Khim, Seock-Kyu, King, Beverly, Kirkland, Thomas, Kochanny, Monica, Liang, Amy, Lentz, Dao, May, Karen, Mendoza, Lisa, Phillips, Gary, Selchau, Victor, Schlyer, Sabine, Tseng, Jih-Lie, Wei, Robert G, Ye, Hong, Parkinson, John, Guilford, William J

“…The synthesis and biological evaluation of a series of N-alkyl glycine amide analogs as LTA sub(4)-h inhibitors and the importance of the introduction of a…”
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Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A 4 hydrolase by Ye, Bin, Bauman, John, Chen, Ming, Davey, David, Khim, Seock-Kyu, King, Beverly, Kirkland, Thomas, Kochanny, Monica, Liang, Amy, Lentz, Dao, May, Karen, Mendoza, Lisa, Phillips, Gary, Selchau, Victor, Schlyer, Sabine, Tseng, Jih-Lie, Wei, Robert G., Ye, Hong, Parkinson, John, Guilford, William J.

“…The synthesis and biological evaluation of a series of N-alkyl glycine amide analogs as LTA 4-h inhibitors and the importance of the introduction of a benzoic…”
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