Search Results - "Wei, Qi"

Precision Medicine, AI, and the Future of Personalized Health Care by Johnson, Kevin B., Wei, Wei‐Qi, Weeraratne, Dilhan, Frisse, Mark E., Misulis, Karl, Rhee, Kyu, Zhao, Juan, Snowdon, Jane L.

“…The convergence of artificial intelligence (AI) and precision medicine promises to revolutionize health care. Precision medicine methods identify phenotypes of…”
Get full text

Learning from Longitudinal Data in Electronic Health Record and Genetic Data to Improve Cardiovascular Event Prediction by Zhao, Juan, Feng, QiPing, Wu, Patrick, Lupu, Roxana A., Wilke, Russell A., Wells, Quinn S., Denny, Joshua C., Wei, Wei-Qi

“…Current approaches to predicting a cardiovascular disease (CVD) event rely on conventional risk factors and cross-sectional data. In this study, we applied…”
Get full text

Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record by Wei, Wei-Qi, Bastarache, Lisa A, Carroll, Robert J, Marlo, Joy E, Osterman, Travis J, Gamazon, Eric R, Cox, Nancy J, Roden, Dan M, Denny, Joshua C

“…To compare three groupings of Electronic Health Record (EHR) billing codes for their ability to represent clinically meaningful phenotypes and to replicate…”
Get full text

Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study by Li, Xue, Meng, Xiangrui, He, Yazhou, Spiliopoulou, Athina, Timofeeva, Maria, Wei, Wei-Qi, Gifford, Aliya, Yang, Tian, Varley, Tim, Tzoulaki, Ioanna, Joshi, Peter, Denny, Joshua C, Mckeigue, Paul, Campbell, Harry, Theodoratou, Evropi

“…The role of urate in cardiovascular diseases (CVDs) has been extensively investigated in observational studies; however, the extent of any causal effect…”
Get full text

Extracting research-quality phenotypes from electronic health records to support precision medicine by Wei, Wei-Qi, Denny, Joshua C

“…The convergence of two rapidly developing technologies - high-throughput genotyping and electronic health records (EHRs) - gives scientists an unprecedented…”
Get full text

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies by Zhou, Wei, Nielsen, Jonas B., Fritsche, Lars G., Dey, Rounak, Gabrielsen, Maiken E., Wolford, Brooke N., LeFaive, Jonathon, VandeHaar, Peter, Gagliano, Sarah A., Gifford, Aliya, Bastarache, Lisa A., Wei, Wei-Qi, Denny, Joshua C., Lin, Maoxuan, Hveem, Kristian, Kang, Hyun Min, Abecasis, Goncalo R., Willer, Cristen J., Lee, Seunggeun

“…In genome-wide association studies (GWAS) for thousands of phenotypes in large biobanks, most binary traits have substantially fewer cases than controls. Both…”
Get full text

Low f‐Number Diffraction‐Limited Pancharatnam–Berry Microlenses Enabled by Plasmonic Photopatterning of Liquid Crystal Polymers by Jiang, Miao, Guo, Yubing, Yu, Hao, Zhou, Ziyuan, Turiv, Taras, Lavrentovich, Oleg D., Wei, Qi‐Huo

“…Microlenses are desired by a wide range of industrial applications while it is always challenging to make them with diffraction‐limited quality. Here, it is…”
Get full text

Association between the PPARGC1A Gly482Ser polymorphism and muscle fitness in Chinese schoolchildren by Wei, Qi

“…Muscle health is essential for children's physical development and future health. PPARGC1A gene encode the peroxisome proliferator-activated receptor…”
Get full text

Multifunctional and Water‐Resistant MXene‐Decorated Polyester Textiles with Outstanding Electromagnetic Interference Shielding and Joule Heating Performances by Wang, Qi‐Wei, Zhang, Hao‐Bin, Liu, Ji, Zhao, Sai, Xie, Xi, Liu, Liuxin, Yang, Rui, Koratkar, Nikhil, Yu, Zhong‐Zhen

“…Although multifunctional, flexible, and wearable textiles with integrated smart electronics have attracted tremendous attention in recent years, it is still an…”
Get full text

Flexible and Multifunctional Silk Textiles with Biomimetic Leaf‐Like MXene/Silver Nanowire Nanostructures for Electromagnetic Interference Shielding, Humidity Monitoring, and Self‐Derived Hydrophobicity by Liu, Liu‐Xin, Chen, Wei, Zhang, Hao‐Bin, Wang, Qi‐Wei, Guan, Fanglan, Yu, Zhong‐Zhen

“…Although flexible and multifunctional textiles are promising for wearable electronics and portable device applications, the main issue is to endow textiles…”
Get full text

Neoproterozoic magmatism in the western and northern margins of the Yangtze Block (South China) controlled by slab subduction and subduction-transform-edge-propagator by Zhao, Jun-Hong, Li, Qi-Wei, Liu, Hang, Wang, Wei

“…The South China Craton consists of the Yangtze and Cathaysia blocks that were welded together along the Jiangnan Fold Belt in the Neoproterozoic. The…”
Get full text

Integrating gene expression and clinical data to identify drug repurposing candidates for hyperlipidemia and hypertension by Wu, Patrick, Feng, QiPing, Kerchberger, Vern Eric, Nelson, Scott D., Chen, Qingxia, Li, Bingshan, Edwards, Todd L., Cox, Nancy J., Phillips, Elizabeth J., Stein, C. Michael, Roden, Dan M., Denny, Joshua C., Wei, Wei-Qi

“…Discovering novel uses for existing drugs, through drug repurposing, can reduce the time, costs, and risk of failure associated with new drug development…”
Get full text

Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects by Gill, Dipender, Georgakis, Marios K, Koskeridis, Fotios, Jiang, Lan, Feng, Qiping, Wei, Wei-Qi, Theodoratou, Evropi, Elliott, Paul, Denny, Joshua C, Malik, Rainer, Evangelou, Evangelos, Dehghan, Abbas, Dichgans, Martin, Tzoulaki, Ioanna

“…BACKGROUND:Drug effects can be investigated through natural variation in the genes for their protein targets. The present study aimed to use this approach to…”
Get full text

Combining billing codes, clinical notes, and medications from electronic health records provides superior phenotyping performance by Wei, Wei-Qi, Teixeira, Pedro L, Mo, Huan, Cronin, Robert M, Warner, Jeremy L, Denny, Joshua C

“…Objective To evaluate the phenotyping performance of three major electronic health record (EHR) components: International Classification of Disease (ICD)…”
Get full text

Mapping ICD-10 and ICD-10-CM Codes to Phecodes: Workflow Development and Initial Evaluation by Wu, Patrick, Gifford, Aliya, Meng, Xiangrui, Li, Xue, Campbell, Harry, Varley, Tim, Zhao, Juan, Carroll, Robert, Bastarache, Lisa, Denny, Joshua C, Theodoratou, Evropi, Wei, Wei-Qi

“…The phecode system was built upon the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) for phenome-wide association…”
Get full text

Using topic modeling via non-negative matrix factorization to identify relationships between genetic variants and disease phenotypes: A case study of Lipoprotein(a) (LPA) by Zhao, Juan, Feng, QiPing, Wu, Patrick, Warner, Jeremy L, Denny, Joshua C, Wei, Wei-Qi

“…Genome-wide and phenome-wide association studies are commonly used to identify important relationships between genetic variants and phenotypes. Most studies…”
Get full text

N-double poles solutions for nonlocal Hirota equation with nonzero boundary conditions using Riemann–Hilbert method and PINN algorithm by Peng, Wei-Qi, Chen, Yong

“…In this paper, we systematically investigate the nonlocal Hirota equation with nonzero boundary conditions via Riemann–Hilbert method and multi-layer…”
Get full text

Traffic sign recognition based on deep learning by Zhu, Yanzhao, Yan, Wei Qi

“…Intelligent Transportation System (ITS), including unmanned vehicles, has been gradually matured despite on road. How to eliminate the interference due to…”
Get full text

A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease by Emdin, Connor A, Haas, Mary E, Khera, Amit V, Aragam, Krishna, Chaffin, Mark, Klarin, Derek, Hindy, George, Jiang, Lan, Wei, Wei-Qi, Feng, Qiping, Karjalainen, Juha, Havulinna, Aki, Kiiskinen, Tuomo, Bick, Alexander, Ardissino, Diego, Wilson, James G, Schunkert, Heribert, McPherson, Ruth, Watkins, Hugh, Elosua, Roberto, Bown, Matthew J, Samani, Nilesh J, Baber, Usman, Erdmann, Jeanette, Gupta, Namrata, Danesh, John, Saleheen, Danish, Chang, Kyong-Mi, Vujkovic, Marijana, Voight, Ben, Damrauer, Scott, Lynch, Julie, Kaplan, David, Serper, Marina, Tsao, Philip, Mercader, Josep, Hanis, Craig, Daly, Mark, Denny, Joshua, Gabriel, Stacey, Kathiresan, Sekar

“…Analyzing 12,361 all-cause cirrhosis cases and 790,095 controls from eight cohorts, we identify a common missense variant in the Mitochondrial Amidoxime…”
Get full text

A Mesoporous Nanoenzyme Derived from Metal–Organic Frameworks with Endogenous Oxygen Generation to Alleviate Tumor Hypoxia for Significantly Enhanced Photodynamic Therapy by Wang, Dongdong, Wu, Huihui, Lim, Wei Qi, Phua, Soo Zeng Fiona, Xu, Pengping, Chen, Qianwang, Guo, Zhen, Zhao, Yanli

“…Tumor hypoxia compromises the therapeutic efficiency of photodynamic therapy (PDT) as the local oxygen concentration plays an important role in the generation…”
Get full text