Search Results - "Wei, Peilan"
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Potent prophylactic and therapeutic efficacy of recombinant human ACE2-Fc against SARS-CoV-2 infection in vivo
Published in Cell discovery (12-08-2021)“…The current COVID-19 pandemic, caused by SARS-CoV-2, poses a serious public health threat. Effective therapeutic and prophylactic treatments are urgently…”
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Antigenic characterization of SARS-CoV-2 Omicron subvariants XBB.1.5, BQ.1, BQ.1.1, BF.7 and BA.2.75.2
Published in Signal transduction and targeted therapy (15-03-2023)Get full text
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Two novel human coronavirus OC43 genotypes circulating in hospitalized children with pneumonia in China
Published in Emerging microbes & infections (01-12-2022)“…HCoV-OC43 is one of the mildly pathogenic coronaviruses with high infection rates in common population. Here, 43 HCoV-OC43 related cases with pneumonia were…”
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Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain
Published in Cell reports (Cambridge) (23-01-2024)“…Omicron, as the emerging variant with enhanced vaccine tolerance, has sharply disrupted most therapeutic antibodies. Severe acute respiratory syndrome…”
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Detection of Anti-SARS-CoV-2-S2 IgG Is More Sensitive Than Anti-RBD IgG in Identifying Asymptomatic COVID-19 Patients
Published in Frontiers in immunology (19-08-2021)“…Characterizing the serologic features of asymptomatic SARS-CoV-2 infection is imperative to improve diagnostics and control of SARS-CoV-2 transmission. In this…”
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Intranasal Lentiviral Vector-Mediated Antibody Delivery Confers Reduction of SARS-CoV-2 Infection in Elderly and Immunocompromised Mice
Published in Frontiers in immunology (22-04-2022)“…Vaccines for COVID-19 are now a crucial public health need, but the degree of protection provided by conventional vaccinations for individuals with compromised…”
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Mouse models susceptible to HCoV-229E and HCoV-NL63 and cross protection from challenge with SARS-CoV-2
Published in Proceedings of the National Academy of Sciences - PNAS (24-01-2023)“…Human coronavirus 229E (HCoV-229E) and NL63 (HCoV-NL63) are endemic causes of upper respiratory infections such as the "common cold" but may occasionally cause…”
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Plasma cell-free DNA promise monitoring and tissue injury assessment of COVID-19
Published in Molecular genetics and genomics : MGG (01-07-2023)“…Coronavirus 2019 (COVID-19) is a complex disease that affects billions of people worldwide. Currently, effective etiological treatment of COVID-19 is still…”
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Trivalent SARS-CoV-2 virus-like particle vaccines exhibit broad-spectrum neutralization and protection against XBB.1 and BA.2.86 variants
Published in Virologica Sinica (01-10-2024)“…•RBDs of the WT, BQ.1.1 and XBB.1 variants were genetically fused and displayed on the VLP to create RBDV14 M.•RBDV14 M can induce superior antibody…”
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Investigating Derivatives of Tanshinone IIA Sulfonate Sodium and Chloroxine for Their Inhibition Activities against the SARS-CoV‑2 Papain-like Protease
Published in ACS omega (27-12-2022)“…SARS-CoV-2 has caused a global pandemic of COVID-19, posing a huge threat to public health. The SARS-CoV-2 papain-like cysteine protease (PLpro) plays a…”
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Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRLIIpr mice via inhibition of TLR-triggered B-cell activation and plasma cell formation
Published in 中国免疫学杂志:英文版 (2016)“…We previously reported that SM934, a water-soluble artemisinin derivative, was a viable treatment in murine lupus models. In the current study, we further…”
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