Search Results - "Wei, Panjian"
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Costimulatory capacity of CD137 mAbs on T cells depends on elaborate CRD structures but not on blocking ligand‒receptor binding
Published in European journal of immunology (01-12-2023)“…CD137 is mainly a costimulatory receptor of CD8+ T cells. Two representative CD137 antibodies, utomilumab, and urelumab, show different costimulatory…”
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The levels of soluble CD137 are increased in tuberculosis patients and associated with disease severity and prognosis
Published in European journal of immunology (01-08-2024)“…Tuberculosis (TB) was the leading cause of death from a single infectious agent before the coronavirus pandemic. Therefore, it is important to search for…”
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Berberine attenuates TNBS-induced colitis in mice by improving the intestinal microbiota
Published in Frontiers in microbiology (29-08-2024)“…To investigate the effects of berberine (BBR) as a treatment on intestinal microecological alterations and enteritis in mice produced by TNBS. There were seven…”
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Establishment of novel anti-TIM-3 antibodies interfering with its binding to ligands
Published in Heliyon (15-04-2024)“…The T cell immunoglobulin and mucin-domain containing-3 (TIM-3) receptor has gained significant attention as a promising target for cancer immunotherapy. The…”
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Elevated Natural Killer Cell-Mediated Cytotoxicity Is Associated with Cavity Formation in Pulmonary Tuberculosis Patients
Published in Journal of immunology research (04-10-2021)“…Cavitation is a major pathological feature of pulmonary tuberculosis (TB). The study is aimed at investigating the mechanism of natural killer (NK) cells…”
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Circulating CD137+CD8+ T cells accumulate along with increased functional regulatory T cells and thoracic tumour burden in lung cancer patients
Published in Scandinavian journal of immunology (01-06-2019)“…CD137 is a promising target for immunostimulation strategies against cancer. Previous studies showed that CD137+CD8+ T cells are enriched in antitumour…”
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Association between response to anti-PD-1 treatment and blood soluble PD-L1 and IL-8 changes in patients with NSCLC
Published in Discover. Oncology (29-03-2023)“…In this study, we explored the dynamic changes in blood sPD-L1 and its clinical value during anti-PD-1 immunotherapy in non-small cell lung cancer (NSCLC)…”
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Enhanced Serum IgG Detection Potential Using 38KD-MPT32-MPT64, CFP10-Mtb81-EspC Fusion Protein and Lipoarabinomannan (LAM) for Human Tuberculosis
Published in Pathogens (Basel) (01-12-2022)“…For the rapid, reliable, and cost-effective methods of tuberculosis (TB) auxiliary diagnosis, antibody (Ab) detection to multiple antigens of (Mtb) has great…”
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Immunoassay with Novel Paired Antibodies for Detection of Lipoarabinomannan in the Pleural Fluid and Plasma of Patients with Tuberculous Pleurisy
Published in Microorganisms (Basel) (01-09-2023)“…Tuberculous pleurisy (TP) is one of the most common forms of extrapulmonary tuberculosis, but its diagnosis is challenging. Lipoarabinomannan (LAM) antigen is…”
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Soluble programmed cell death-ligand 1 as a new potential biomarker associated with acute coronary syndrome
Published in Frontiers in cardiovascular medicine (02-09-2022)“…Background Soluble programmed cell death-ligand 1 (sPD-L1) has been well documented to activate immunosuppression and is considered an essential predictor of…”
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T-cell subsets and cytokines are indicative of neoadjuvant chemoimmunotherapy responses in NSCLC
Published in Cancer Immunology, Immunotherapy : CII (15-04-2024)“…Purpose Neoadjuvant PD-1 blockade combined with chemotherapy is a promising treatment for resectable non-small cell lung cancer (NSCLC), yet the immunological…”
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Cancer-associated fibroblasts: heterogeneity and their role in the tumor immune response
Published in Clinical and experimental medicine (12-06-2024)“…In recent decades, many reports have been published on the composition and function of the tumor microenvironment (TME), among which cancer-associated…”
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Pathological complete response to neoadjuvant chemoimmunotherapy correlates with peripheral blood immune cell subsets and metastatic status of mediastinal lymph nodes (N2 lymph nodes) in non-small cell lung cancer
Published in Lung cancer (Amsterdam, Netherlands) (01-10-2022)“…•A retrospective study of 59 patients with resectable stage IIA-IIIB NSCLC who were treated with neoadjuvant chemo-immunotherapy.•N2 metastases were less…”
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Human umbilical cord mesenchymal stem cells alleviated TNBS-induced colitis in mice by restoring the balance of intestinal microbes and immunoregulation
Published in Life sciences (1973) (01-12-2023)“…Human umbilical cord mesenchymal stem cells (HUMSCs) have been documented to be effective for several immune disorders including inflammatory bowel diseases…”
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Preparation of two types p53 recombinant adenovirus and quantitative exogenous expression of green fluorescence protein by flow cytometry
Published in Zhongguo fei ai za zhi (01-05-2010)“…The p53 as a transcription factor in cell stress was activated to regulate cell cycle and programmed cell death to inhibit tumor growth. Usually, p53 is kept…”
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Preparation of Two Types p53 Recombinant Adenovirus and Quantitative Exogenous Expression of Green Fluorescence Protein by Flow Cytometry
Published in Zhongguo fei ai za zhi (01-05-2010)“…背景与目的 p53作为转录因子,在细胞应激时呈活化型,可调控细胞周期和程序性死亡抑制肿瘤生长,通常通过各种机制可使p53呈现非活化状态,其中包括p53 C-末端负调控序列的作用。本研究旨在制备携带全长和缺失这些负调控序列p53的两种重组腺病毒,并采用流式细胞仪散点图(flow cytometry scatter…”
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