Search Results - "Wei, Miaoyan"

A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance by Meng, Qingcai, Liang, Chen, Hua, Jie, Zhang, Bo, Liu, Jiang, Zhang, Yiyin, Wei, Miaoyan, Yu, Xianjun, Xu, Jin, Shi, Si

“…: Dysregulated microRNA (miRNA) expression in cancer can act as a key factor that modifies biological processes, including chemoresistance. Our study aimed to…”
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PARP inhibitors in pancreatic cancer: molecular mechanisms and clinical applications by Zhu, Heng, Wei, Miaoyan, Xu, Jin, Hua, Jie, Liang, Chen, Meng, Qingcai, Zhang, Yiyin, Liu, Jiang, Zhang, Bo, Yu, Xianjun, Shi, Si

“…Pancreatic cancer is a highly lethal disease with a poor prognosis, and existing therapies offer only limited effectiveness. Mutation gene sequencing has shown…”
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Simultaneous resection of the primary tumour and liver metastases after conversion chemotherapy versus standard therapy in pancreatic cancer with liver oligometastasis: protocol of a multicentre, prospective, randomised phase III control trial (CSPAC-1) by Wei, Miaoyan, Shi, Si, Hua, Jie, Xu, Jin, Yu, Xianjun

“…IntroductionApproximately 50% of pancreatic ductal adenocarcinoma (PDAC) patients are diagnosed with distant metastasis, especially liver metastasis. The…”
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Phase 1b study of first-line fuzuloparib combined with modified FOLFIRINOX followed by fuzuloparib maintenance monotherapy in pancreatic adenocarcinoma by Wei, Miaoyan, Liu, Rujiao, Xu, Yunyun, Chen, Xiaobing, Liu, Chao, Bai, Xueli, Zhang, Xiaochen, Gao, Shuiping, Li, Jialin, Sheng, Zhen, Lian, Jianpo, Wang, Wenliang, Zhang, Jian, Shi, Si, Xu, Jin, Yu, Xianjun

“…Chemotherapy remains the standard first-line treatment for pancreatic adenocarcinoma, but with limited efficacy. We aimed to explore the feasibility of adding…”
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Comprehensive analysis of the prognosis and immune infiltration landscape of RNA methylation-related subtypes in pancreatic cancer by Lu, Siyuan, Hua, Jie, Liu, Jiang, Wei, Miaoyan, Liang, Chen, Meng, Qingcai, Zhang, Bo, Yu, Xianjun, Wang, Wei, Xu, Jin

“…RNA methylation refers to a form of methyl modification in RNA that modulates various epigenetic alterations. Mounting studies have focused on its potential…”
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Mitochondria-Related Transcriptome Characterization Associated with the Immune Microenvironment, Therapeutic Response and Survival Prediction in Pancreatic Cancer by Dong, Jia, Liu, Jiang, Zhang, Bo, Liang, Chen, Hua, Jie, Meng, Qingcai, Wei, Miaoyan, Wang, Wei, Yu, Xianjun, Xu, Jin

“…(1) Background: Pancreatic cancer (PC) is one of the most lethal tumors. Mitochondrial dysfunction has been reported to be involved in cancer development;…”
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The value of a metabolic reprogramming-related gene signature for pancreatic adenocarcinoma prognosis prediction by Tan, Zhen, Lei, Yubin, Xu, Jin, Shi, Si, Hua, Jie, Zhang, Bo, Meng, Qingcai, Liu, Jiang, Zhang, Yiyin, Wei, Miaoyan, Yu, Xianjun, Liang, Chen

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal malignancies worldwide. Extensive enhancement of glycolysis and reprogramming of lipid…”
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From the Immune Profile to the Immunoscore: Signatures for Improving Postsurgical Prognostic Prediction of Pancreatic Neuroendocrine Tumors by Wei, Miaoyan, Xu, Jin, Hua, Jie, Meng, Qingcai, Liang, Chen, Liu, Jiang, Zhang, Bo, Wang, Wei, Yu, Xianjun, Shi, Si

“…Immune infiltration plays an important role in tumor development and progression and shows promising prognostic value in numerous tumors. In this study, we…”
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Radical antegrade modular pancreatosplenectomy (RAMPS) versus standard retrograde pancreatosplenectomy (SRPS) for resectable body and tail pancreatic adenocarcinoma: protocol of a multicenter, prospective, randomized phase III control trial (CSPAC-3) by Li, Jialin, Shi, Si, Liu, Jiang, Liang, Chen, Hua, Jie, Meng, Qingcai, Xu, Hang, Wei, Miaoyan, Zhang, Bo, Xu, Jin, Wang, Wei, Yu, Xianjun

“…Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Radical surgical resection offers the only potential cure. There is increasing…”
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Intra-tumoral infiltration of adipocyte facilitates the activation of antitumor immune response in pancreatic ductal adenocarcinoma by Liu, Xiaomeng, Liu, Jiang, Xu, Jin, Zhang, Bo, Wei, Miaoyan, Li, Jialin, Xu, Hang, Yu, Xianjun, Wang, Wei, Shi, Si

“…•High adipocyte infiltration in the tumor microenvironment (TME) is related to significantly increased median overall survival and lower total tumor mutational…”
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A PD-L2-based immune marker signature helps to predict survival in resected pancreatic ductal adenocarcinoma by Zhang, Yiyin, Xu, Jin, Hua, Jie, Liu, Jiang, Liang, Chen, Meng, Qingcai, Wei, Miaoyan, Zhang, Bo, Yu, Xianjun, Shi, Si

“…Programmed cell death protein 1 (PD-1) is a key immune checkpoint that regulates peripheral tolerance and protects against autoimmunity. Programmed death…”
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Generation of An Endogenous FGFR2-BICC1 Gene Fusion/58 Megabase Inversion Using Single-Plasmid CRISPR/Cas9 Editing in Biliary Cells by Reicher, Andreas, Harris, Antoneicka L, Prinz, Felix, Kiesslich, Tobias, Wei, Miaoyan, Öllinger, Rupert, Rad, Roland, Pichler, Martin, Kwong, Lawrence N

“…Fibroblast growth factor receptor 2 ( ) gene fusions are oncogenic drivers in 10-15% of intrahepatic cholangiocarcinoma (CCA), yet currently there are no cell…”
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Validation and head-to-head comparison of four models for predicting malignancy in intraductal papillary mucinous neoplasms of the pancreas: a study based on endoscopic ultrasound findings by Hua, Jie, Shi, Si, Zhang, Yiyin, Wei, Miaoyan, Liang, Chen, Meng, Qingcai, Liu, Jiang, Zhang, Bo, Xu, Jin, Yang, Xiujiang, Yu, Xianjun

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A Novel Validated Recurrence Stratification System Based on 18F-FDG PET/CT Radiomics to Guide Surveillance After Resection of Pancreatic Cancer by Wei, Miaoyan, Gu, Bingxin, Song, Shaoli, Zhang, Bo, Wang, Wei, Xu, Jin, Yu, Xianjun, Shi, Si

“…objective Despite the heterogeneous biology of pancreatic cancer, similar surveillance schemas have been used. Identifying the high recurrence risk population…”
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Turning towards nonimmunoreactive tumors: Evaluation of cancer-associated fibroblasts enables prediction of the immune microenvironment and treatment sensitivity in pancreatic cancer by Lu, Siyuan, Hua, Jie, Xu, Jin, Wei, Miaoyan, Liang, Chen, Meng, Qingcai, Liu, Jiang, Zhang, Bo, Wang, Wei, Yu, Xianjun, Shi, Si

“…[Display omitted] •We identified FGFR4 as a potential oncogene and CAFs target in pancreatic cancer.•The study firstly utilized the fusion dataset to improve…”
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Expression Patterns and Prognostic Value of DNA Damage Repair Proteins in Resected Pancreatic Neuroendocrine Neoplasms by Hua, Jie, Shi, Si, Xu, Jin, Wei, Miaoyan, Zhang, Yiyin, Liu, Jiang, Zhang, Bo, Yu, Xianjun

“…OBJECTIVE:This study aimed to examine the expression profiles and prognostic value of multiple DDR proteins in resected PanNENs. BACKGROUND:DDR proteins play…”
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Characteristics of Abdominal Symptoms in Post Laparoscopic Cholecystectomy Patients: A Multi-Centered Cross-Sectional Study in Shanghai by Tang, Zhaohui, Wei, Miaoyan, Quan, Zhiwei

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Mo1352 - Characteristics of Abdominal Symptoms in Post Laparoscopic Cholecystectomy Patients: A Multi-Centered Cross-Sectional Study in Shanghai by Tang, Zhaohui, Wei, Miaoyan, Quan, Zhiwei

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Multiple cellular origins and molecular evolution of intrahepatic cholangiocarcinoma by Wei, Miaoyan, Lü, Lisheng, Lin, Peiyi, Chen, Zhisheng, Quan, Zhiwei, Tang, Zhaohui

“…Highlights • ICC is a heterogeneous cancer in epidemiology, morphology, pathology and molecular biology. • Cancer cell origin affects tumor cell fate and ICC…”
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Prospective observational study on biomarkers of response in pancreatic ductal adenocarcinoma by Jiang, Lingxi, Qin, Jiejie, Dai, Yuting, Zhao, Shulin, Zhan, Qian, Cui, Peng, Ren, Lingjie, Wang, Xuelong, Zhang, Ruihong, Gao, Chenxu, Zhou, Yanting, Cai, Shangli, Wang, Guoqiang, Xie, Wenchuan, Tang, Xiaomei, Shi, Minmin, Ma, Fangfang, Liu, Jia, Wang, Ting, Wang, Chaofu, Svrcek, Magali, Bardier-Dupas, Armelle, Emile, Jean Francois, de Mestier, Louis, Bachet, Jean-Baptiste, Nicolle, Remy, Cros, Jerome, Laurent-Puig, Pierre, Wei, Miaoyan, Song, Bin, Jing, Wei, Guo, Shiwei, Zheng, Kailian, Jiang, Hui, Wang, Huan, Deng, Xiaxing, Chen, Hao, Tian, Qiang, Wang, Shengyue, Shi, Si, Jin, Gang, Yin, Tong, Fang, Hai, Chen, Saijuan, Shen, Baiyong

“…Adjuvant chemotherapy benefits patients with resected pancreatic ductal adenocarcinoma (PDAC), but the compromised physical state of post-operative patients…”
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