Search Results - "Wei, John T"
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Benign Prostatic Hyperplasia and Lower Urinary Tract Symptoms
Published in The New England journal of medicine (19-07-2012)“…Lower urinary tract symptoms affect more than half of older men. Options for bothersome symptoms include α-adrenergic-receptor blockers, 5α-reductase…”
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2
Beyond PSA: the next generation of prostate cancer biomarkers
Published in Science translational medicine (28-03-2012)“…Since the introduction of serum prostate-specific antigen (PSA) screening 25 years ago, prostate cancer diagnosis and management have been guided by this…”
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3
Radical Prostatectomy versus Observation for Localized Prostate Cancer
Published in The New England journal of medicine (19-07-2012)“…Over 700 men were assigned to radical prostatectomy or observation after receiving a diagnosis of prostate cancer, usually on the basis of elevated PSA levels…”
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4
Analysis of the androgen receptor–regulated lncRNA landscape identifies a role for ARLNC1 in prostate cancer progression
Published in Nature genetics (01-06-2018)“…The androgen receptor (AR) plays a critical role in the development of the normal prostate as well as prostate cancer. Using an integrative transcriptomic…”
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5
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1 , an unannotated lincRNA implicated in disease progression
Published in Nature biotechnology (01-08-2011)“…New noncoding RNAs can be discovered by assembling transcripts from RNA-Seq data. Prensner et al . apply this approach across >100 prostate cancer samples to…”
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6
A Midurethral Sling to Reduce Incontinence after Vaginal Prolapse Repair
Published in The New England journal of medicine (21-06-2012)“…Women undergoing surgery for vaginal prolapse are at risk for urinary incontinence. In this randomized trial, women who received a midurethral sling had lower…”
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7
The Prostate Health Index Selectively Identifies Clinically Significant Prostate Cancer
Published in The Journal of urology (01-04-2015)“…Purpose The Prostate Health Index (phi) is a new test combining total, free and [-2]proPSA into a single score. It was recently approved by the FDA and is now…”
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Minimally Important Difference for the Expanded Prostate Cancer Index Composite Short Form
Published in Urology (Ridgewood, N.J.) (2015)“…Objective To establish a score threshold that constitutes a clinically relevant change for each domain of the Expanded Prostate Cancer Index Composite (EPIC)…”
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Can urinary PCA3 supplement PSA in the early detection of prostate cancer?
Published in Journal of clinical oncology (20-12-2014)“…Given the limited sensitivity and specificity of prostate-specific antigen (PSA), its widespread use as a screening tool has raised concerns for the…”
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10
AUA White Paper on Nonneurogenic Chronic Urinary Retention: Consensus Definition, Treatment Algorithm, and Outcome End Points
Published in The Journal of urology (01-07-2017)“…Purpose The AUA (American Urological Association) QIPS (Quality Improvement and Patient Safety) committee created a white paper on the diagnosis and management…”
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11
RNA biomarkers associated with metastatic progression in prostate cancer: a multi-institutional high-throughput analysis of SChLAP1
Published in The lancet oncology (01-12-2014)“…Summary Background Improved clinical predictors for disease progression are needed for localised prostate cancer, since only a subset of patients develop…”
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12
Prediction of Erectile Function Following Treatment for Prostate Cancer
Published in JAMA : the journal of the American Medical Association (21-09-2011)“…CONTEXT Sexual function is the health-related quality of life (HRQOL) domain most commonly impaired after prostate cancer treatment; however, validated tools…”
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13
Medical therapy to facilitate urinary stone passage: a meta-analysis
Published in The Lancet (British edition) (30-09-2006)“…Medical therapies to ease urinary-stone passage have been reported, but are not generally used. If effective, such therapies would increase the options for…”
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14
Prognostic Value of Percent Gleason Grade 4 at Prostate Biopsy in Predicting Prostatectomy Pathology and Recurrence
Published in The Journal of urology (01-08-2016)“…Purpose The importance of primary Gleason grade among men with Gleason score 7 disease has been well-defined. However, this dichotomization may oversimplify…”
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15
Use of Advanced Treatment Technologies Among Men at Low Risk of Dying From Prostate Cancer
Published in JAMA : the journal of the American Medical Association (26-06-2013)“…IMPORTANCE The use of advanced treatment technologies (ie, intensity-modulated radiotherapy [IMRT] and robotic prostatectomy) for prostate cancer is…”
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16
A First-Generation Multiplex Biomarker Analysis of Urine for the Early Detection of Prostate Cancer
Published in Cancer research (Chicago, Ill.) (01-02-2008)“…Although prostate-specific antigen (PSA) serum level is currently the standard of care for prostate cancer screening in the United States, it lacks ideal…”
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17
Nocturia and Quality of Life: Results from the Boston Area Community Health Survey
Published in European urology (01-01-2012)“…Abstract Background Nocturia, a common complaint in aging men and women, is frequently cited as the cause of nocturnal awakenings leading to sleep loss,…”
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The Role of Sarcosine Metabolism in Prostate Cancer Progression
Published in Neoplasia (New York, N.Y.) (01-05-2013)“…Abstract Metabolomic profiling of prostate cancer (PCa) progression identified markedly elevated levels of sarcosine ( N -methyl glycine) in metastatic PCa and…”
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Variation in use of active surveillance among men undergoing expectant treatment for early stage prostate cancer
Published in The Journal of urology (01-07-2014)“…We examined variation in active surveillance use in Medicare eligible men undergoing expectant treatment for early stage prostate cancer. Using SEER…”
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Combining urinary detection of TMPRSS2:ERG and PCA3 with serum PSA to predict diagnosis of prostate cancer
Published in Urologic oncology (01-07-2013)“…Abstract Objectives We sought to develop a clinical algorithm combining serum PSA with detection of TMPRSS2:ERG fusion and PCA3 in urine collected after…”
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