Search Results - "Wei, Iris"

Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy by Garcia-Aguilar, Julio, Patil, Sujata, Gollub, Marc J, Kim, Jin K, Yuval, Jonathan B, Thompson, Hannah M, Verheij, Floris S, Omer, Dana M, Lee, Meghan, Dunne, Richard F, Marcet, Jorge, Cataldo, Peter, Polite, Blase, Herzig, Daniel O, Liska, David, Oommen, Samuel, Friel, Charles M, Ternent, Charles, Coveler, Andrew L, Hunt, Steven, Gregory, Anita, Varma, Madhulika G, Bello, Brian L, Carmichael, Joseph C, Krauss, John, Gleisner, Ana, Paty, Philip B, Weiser, Martin R, Nash, Garrett M, Pappou, Emmanouil, Guillem, José G, Temple, Larissa, Wei, Iris H, Widmar, Maria, Lin, Sabrina, Segal, Neil H, Cercek, Andrea, Yaeger, Rona, Smith, J Joshua, Goodman, Karyn A, Wu, Abraham J, Saltz, Leonard B

“…Prospective data on the efficacy of a watch-and-wait strategy to achieve organ preservation in patients with locally advanced rectal cancer treated with total…”
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Programme of self-reactive innate-like T cell-mediated cancer immunity by Chou, Chun, Zhang, Xian, Krishna, Chirag, Nixon, Briana G., Dadi, Saida, Capistrano, Kristelle J., Kansler, Emily R., Steele, Miranda, Han, Jian, Shyu, Amy, Zhang, Jing, Stamatiades, Efstathios G., Liu, Ming, Li, Shun, Do, Mytrang H., Edwards, Chaucie, Kang, Davina S., Chen, Chin-Tung, Wei, Iris H., Pappou, Emmanouil P., Weiser, Martin R., Garcia-Aguilar, J., Smith, J. Joshua, Leslie, Christina S., Li, Ming O.

“…Cellular transformation induces phenotypically diverse populations of tumour-infiltrating T cells 1 – 5 , and immune checkpoint blockade therapies…”
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MRI Assessment of Extramural Venous Invasion Before and After Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer and Its Association with Disease-Free and Overall Survival by Thompson, Hannah M., Bates, David D. B., Pernicka, Jennifer Golia, Park, Sun Jin, Nourbakhsh, Mahra, Fuqua, James L., Fiasconaro, Megan, Lavery, Jessica A., Wei, Iris H., Pappou, Emmanouil P., Smith, J. Joshua, Nash, Garrett M., Weiser, Martin R., Paty, Philip B., Garcia-Aguilar, Julio, Widmar, Maria

“…Background Extramural venous invasion (EMVI) on baseline MRI is associated with poor prognosis in patients with locally advanced rectal cancer. This study…”
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Long-Term Results of Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy: The Randomized Phase II OPRA Trial by Verheij, Floris S, Omer, Dana M, Williams, Hannah, Lin, Sabrina T, Qin, Li-Xuan, Buckley, James T, Thompson, Hannah M, Yuval, Jonathan B, Kim, Jin K, Dunne, Richard F, Marcet, Jorge, Cataldo, Peter, Polite, Blase, Herzig, Daniel O, Liska, David, Oommen, Samuel, Friel, Charles M, Ternent, Charles, Coveler, Andrew L, Hunt, Steven, Gregory, Anita, Varma, Madhulika G, Bello, Brian L, Carmichael, Joseph C, Krauss, John, Gleisner, Ana, Guillem, José G, Temple, Larissa, Goodman, Karyn A, Segal, Neil H, Cercek, Andrea, Yaeger, Rona, Nash, Garrett M, Widmar, Maria, Wei, Iris H, Pappou, Emmanouil P, Weiser, Martin R, Paty, Philip B, Smith, J Joshua, Wu, Abraham J, Gollub, Marc J, Saltz, Leonard B, Garcia-Aguilar, Julio

“…JCO To assess long-term risk of local tumor regrowth, we report updated organ preservation rate and oncologic outcomes of the OPRA trial (ClinicalTrials.gov…”
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Patient-Reported Bowel Function in Patients With Rectal Cancer Managed by a Watch-and-Wait Strategy After Neoadjuvant Therapy: A Case–Control Study by Quezada-Diaz, Felipe F., Smith, J. Joshua, Jimenez-Rodriguez, Rosa M., Wasserman, Isaac, Pappou, Emmanouil P., Patil, Sujata, Wei, Iris H., Nash, Garrett M., Guillem, Jose G., Weiser, Martin R., Paty, Philip B., Garcia-Aguilar, Julio

“…BACKGROUND:A watch-and-wait strategy is a nonoperative alternative to sphincter-preserving surgery for patients with locally advanced rectal cancer who achieve…”
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Quality of life and function after rectal cancer surgery with and without sphincter preservation by Pappou, Emmanouil P, Temple, Larissa K, Patil, Sujata, Smith, J Joshua, Wei, Iris H, Nash, Garrett M, Guillem, José G, Widmar, Maria, Weiser, Martin R, Paty, Philip B, Schrag, Deborah, Garcia-Aguilar, Julio

“…Despite improvements in surgical techniques, functional outcomes and quality of life after therapy for rectal cancer remain suboptimal. We sought to…”
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Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer by Chatila, Walid K., Kim, Jin K., Walch, Henry, Marco, Michael R., Chen, Chin-Tung, Wu, Fan, Omer, Dana M., Khalil, Danny N., Ganesh, Karuna, Qu, Xuan, Luthra, Anisha, Choi, Seo-Hyun, Ho, Yu-Jui, Kundra, Ritika, Groves, Katharine I., Chow, Oliver S., Cercek, Andrea, Weiser, Martin R., Widmar, Maria, Wei, Iris H., Pappou, Emmanouil P., Nash, Garrett M., Paty, Philip B., Shi, Qian, Vakiani, Efsevia, Duygu Selcuklu, S., Donoghue, Mark T. A., Solit, David B., Berger, Michael F., Shia, Jinru, Pelossof, Raphael, Romesser, Paul B., Yaeger, Rona, Smith, J. Joshua, Schultz, Nikolaus, Sanchez-Vega, Francisco, Garcia-Aguilar, Julio

“…The incidence of rectal cancer is increasing in patients younger than 50 years. Locally advanced rectal cancer is still treated with neoadjuvant radiation,…”
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Clinical Calculator Based on Molecular and Clinicopathologic Characteristics Predicts Recurrence Following Resection of Stage I-III Colon Cancer by Weiser, Martin R, Hsu, Meier, Bauer, Philip S, Chapman, Jr, William C, González, Iván A, Chatterjee, Deyali, Lingam, Deepak, Mutch, Matthew G, Keshinro, Ajaratu, Shia, Jinru, Vakiani, Efsevia, Konishi, Tsuyoshi, Shimada, Yoshifumi, Stadler, Zsofia, Segal, Neil H, Cercek, Andrea, Saltz, Leonard, Yaeger, Rona, Varghese, Anna, Widmar, Maria, Wei, Iris H, Pappou, Emmanouil P, Smith, J Joshua, Nash, Garrett, Paty, Philip, Garcia-Aguilar, Julio, Gonen, Mithat

“…Clinical calculators and nomograms have been endorsed by the American Joint Committee on Cancer (AJCC), as they provide the most individualized and accurate…”
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Assessing Endoscopic Response in Locally Advanced Rectal Cancer Treated with Total Neoadjuvant Therapy: Development and Validation of a Highly Accurate Convolutional Neural Network by Williams, Hannah, Thompson, Hannah M., Lee, Christina, Rangnekar, Aneesh, Gomez, Jorge T., Widmar, Maria, Wei, Iris H., Pappou, Emmanouil P., Nash, Garrett M., Weiser, Martin R., Paty, Philip B., Smith, J. Joshua, Veeraraghavan, Harini, Garcia-Aguilar, Julio

“…Background Rectal tumors display varying degrees of response to total neoadjuvant therapy (TNT). We evaluated the performance of a convolutional neural network…”
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Comparison of Robotic, Laparoscopic, and Open Resections of Nonmetastatic Colon Cancer by Yuval, Jonathan B., Thompson, Hannah M., Verheij, Floris S., Fiasconaro, Megan, Patil, Sujata, Widmar, Maria, Wei, Iris H., Pappou, Emmanouil P., Smith, J. Joshua, Nash, Garrett M., Weiser, Martin R., Paty, Philip B., Garcia-Aguilar, Julio

“…Laparoscopic resection for colon cancer has not been associated with improvements in oncological outcomes in comparison to open resection. Robotic resections…”
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Tumor-Associated Macrophages Are a Useful Biomarker to Predict Recurrence After Surgical Resection of Nonfunctional Pancreatic Neuroendocrine Tumors by Wei, Iris H, Harmon, Charles M, Arcerito, Massimo, Cheng, Debbie F, Minter, Rebecca M, Simeone, Diane M

“…OBJECTIVE:Patients with nonfunctional pancreatic neuroendocrine tumors (NF-PNETs) have poorer survival than those with functional PNETs. Our objective was to…”
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ASO Visual Abstract: Assessing Endoscopic Response in Locally Advanced Rectal Cancer Treated with Total Neoadjuvant Therapy: Development and Validation of a Highly Accurate Convolutional Neural Network by Williams, Hannah, Thompson, Hannah M., Lee, Christina, Rangnekar, Aneesh, Gomez, Jorge T., Widmar, Maria, Wei, Iris H., Pappou, Emmanouil P., Nash, Garrett M., Weiser, Martin R., Paty, Philip B., Smith, J. Joshua, Veeraraghavan, Harini, Garcia-Aguilar, Julio

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Lymph Node Metastases and Associated Recurrence-Free Survival in Microsatellite Stable and Unstable Colon Cancer by Hakki, Lynn, Khan, Asama, Gonen, Mithat, Stadler, Zsofia, Segal, Neil H., Shia, Jinru, Widmar, Maria, Wei, Iris H., Smith, J. Joshua, Pappou, Emmanouil P., Nash, Garrett M., Paty, Philip B., Garcia-Aguilar, Julio, Weiser, Martin R.

“…Background In contrast to microsatellite stable (MSS) colon cancer, predictors of lymph node metastases and their association with recurrence are not…”
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Comparison of perioperative outcomes between colorectal operations performed on weekends vs those performed on weekdays by Liu, Siyao, Pappou, Emmanouil P., Cadwell, Joshua B., Kwon, Steve, Seier, Kenneth, Tan, Kay See, Malhotra, Vivek Tim, Wei, Iris H., Widmar, Maria, Smith, J. Joshua, Afonso, Anoushka M.

“…Weekend surgical time is an underused asset. Concerns over a possible weekend effect (substandard care) may be a barrier. This study examined whether a weekend…”
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Validation of a Clinical Calculator Predicting Freedom From Colon Cancer Recurrence After Surgery on the Basis of Molecular and Clinical Variables by Khan, Asama, Thompson, Hannah M, Hsu, Meier, Widmar, Maria, Wei, Iris H, Pappou, Emmanouil, Smith, J Joshua, Nash, Garrett M, Paty, Philip B, Garcia-Aguilar, Julio, Shia, Jinru, Gönen, Mithat, Weiser, Martin R

“…The Memorial Sloan Kettering clinical calculator for estimating the likelihood of freedom from colon cancer recurrence on the basis of clinical and molecular…”
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RNA-Seq Accurately Identifies Cancer Biomarker Signatures to Distinguish Tissue of Origin by Wei, Iris H, Shi, Yang, Jiang, Hui, Kumar-Sinha, Chandan, Chinnaiyan, Arul M

“…Abstract Metastatic cancer of unknown primary (CUP) accounts for up to 5% of all new cancer cases, with a 5-year survival rate of only 10%. Accurate…”
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ASO Visual Abstract: Outcomes of Distal Rectal Cancer Patients Who Did Not Qualify for Watch-and-Wait—Comparison of Intersphincteric Resection Versus Abdominoperineal Resection by Feferman, Yael, Verheij, Floris S., Williams, Hannah, Omer, Dana M., Pappou, Emmanouil P., Wei, Iris H., Widmar, Maria, Nash, Garrett M., Paty, Philip B., Smith, J. Joshua, Cercek, Andrea, Yaeger, Rona, Segal, Neil H., Romesser, Paul B., Crane, Christopher, Saltz, Leonard B., Weiser, Martin R., Garcia-Aguilar, Julio

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Outcomes of Distal Rectal Cancer Patients Who Did Not Qualify for Watch-and-Wait: Comparison of Intersphincteric Resection Versus Abdominoperineal Resection by Feferman, Yael, Verheij, Floris S, Williams, Hannah, Omer, Dana M, Pappou, Emmanouil P, Wei, Iris H, Widmar, Maria, Nash, Garrett M, Paty, Philip B, Smith, J Joshua, Cercek, Andrea, Yaeger, Rona, Segal, Neil H, Romesser, Paul B, Crane, Christopher, Saltz, Leonard B, Weiser, Martin R, Garcia-Aguilar, Julio

“…Total mesorectal excision (TME) with intersphincteric resection and handsewn coloanal anastomosis (ISR-CAA) has been shown to be oncologically safe in patients…”
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ASO Visual Abstract: Lymph Node Metastases and Associated Recurrence-Free Survival in Microsatellite Stable and Unstable Colon Cancer by Hakki, Lynn, Khan, Asama, Gonen, Mithat, Stadler, Zsofia, Segal, Neil H., Shia, Jinru, Widmar, Maria, Wei, Iris H., Smith, J. Joshua, Pappou, Emmanouil P., Nash, Garrett M., Paty, Philip B., Garcia-Aguilar, Julio, Weiser, Martin R.

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MRI at Restaging After Neoadjuvant Therapy for Rectal Cancer Overestimates Circumferential Resection Margin Proximity as Determined by Comparison With Whole-Mount Pathology by Yuval, Jonathan B., Thompson, Hannah M., Firat, Canan, Verheij, Floris S., Widmar, Maria, Wei, Iris H., Pappou, Emmanouil, Smith, J. Joshua, Weiser, Martin R., Paty, Philip B., Nash, Garrett M., Shia, Jinru, Gollub, Marc J., Garcia-Aguilar, Julio

“…Current guidelines recommend restaging with MRI after neoadjuvant therapy for rectal cancer, but the accuracy of restaging MRI in estimating circumferential…”
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