Search Results - "Wei, Cuibai"
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Dementia in China: epidemiology, clinical management, and research advances
Published in Lancet neurology (01-01-2020)“…China has the largest population of patients with dementia in the world, imposing a heavy burden on the public and health care systems. More than 100…”
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Blood neuro‐exosomal synaptic proteins predict Alzheimer's disease at the asymptomatic stage
Published in Alzheimer's & dementia (01-01-2021)“…Introduction Exosomes are an emerging candidate for biomarkers of Alzheimer's disease (AD). This study investigated whether exosomal synaptic proteins can…”
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The cost of Alzheimer's disease in China and re-estimation of costs worldwide
Published in Alzheimer's & dementia (01-04-2018)“…The socioeconomic costs of Alzheimer's disease (AD) in China and its impact on global economic burden remain uncertain. We collected data from 3098 patients…”
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The prevalence of dementia in urban and rural areas of China
Published in Alzheimer's & dementia (01-01-2014)“…Abstract Objective The Chinese population has been aging rapidly and the country's economy has experienced exponential growth during the past three decades…”
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Safety and Efficacy of Donepezil 10 mg/day in Patients with Mild to Moderate Alzheimer's Disease
Published in Journal of Alzheimer's disease (01-01-2020)“…Efficacy and dose-effect relationship of donepezil for treating patients with Alzheimer's disease (AD) have been proven. However, few studies focused on the…”
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Brains of rhesus monkeys display Aβ deposits and glial pathology while lacking Aβ dimers and other Alzheimer's pathologies
Published in Aging cell (01-08-2019)“…Cerebral amyloid beta (Aβ) deposits are the main early pathology of Alzheimer's disease (AD). However, abundant Aβ deposits also occur spontaneously in the…”
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Characteristics and Transcriptomic Analysis of Cholinergic Neurons Derived from Induced Pluripotent Stem Cells with APP Mutation in Alzheimer's Disease
Published in Journal of Alzheimer's disease (01-01-2024)“…The cholinergic hypothesis is one of the main theories that describe the pathogenesis of Alzheimer's disease (AD). Cholinergic neurons degenerate early and are…”
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Monetary costs of Alzheimer's disease in China: protocol for a cluster-randomised observational study
Published in BMC neurology (25-01-2017)“…Alzheimer's disease (AD) is the most common type of dementia. International multilateral cost-of-illness (COI) studies have revealed that the cost of treating…”
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A Novel PSEN1 K311R Mutation Discovered in Chinese Families with Late-Onset Alzheimer's Disease Affects Amyloid-β Production and Tau Phosphorylation
Published in Journal of Alzheimer's disease (01-01-2017)“…Presenilin-1 (PSEN1) is the most frequently mutated gene in familial Alzheimer's disease (AD), whereas only several novel mutations have been reported in China…”
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Prediction of Alzheimer's disease using multi-variants from a Chinese genome-wide association study
Published in Brain (London, England : 1878) (12-04-2021)“…Previous genome-wide association studies have identified dozens of susceptibility loci for sporadic Alzheimer's disease, but few of these loci have been…”
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The prevalence of mild cognitive impairment and its etiological subtypes in elderly Chinese
Published in Alzheimer's & dementia (01-07-2014)“…Abstract Background Epidemiologic studies on mild cognitive impairment (MCI) are limited in China. Methods Using a multistage cluster sampling design, a total…”
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Proteomic profiling of circulating plasma exosomes reveals novel biomarkers of Alzheimer's disease
Published in Alzheimer's research & therapy (05-12-2022)“…Neuronal- and astrocyte-derived exosomes have been identified as an optimal source for screening biomarkers for Alzheimer's disease (AD). However, few studies…”
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White Matter Fractional Anisotropy Is a Superior Predictor for Cognitive Impairment Than Brain Volumes in Older Adults With Confluent White Matter Hyperintensities
Published in Frontiers in psychiatry (05-05-2021)“…Older patients with confluent white matter hyperintensities (WMHs) on magnetic resonance imaging have an increased risk for the onset of vascular cognitive…”
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Bibliometric analysis of neuroinflammation and Alzheimer's disease
Published in Frontiers in aging neuroscience (15-07-2024)“…Alzheimer's disease (AD) is the predominant cause of dementia on a global scale, significantly impacting the health of the elderly population. The pathogenesis…”
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Neurosarcoidosis: clinical characteristics, diagnosis, and treatment in eight Chinese patients
Published in Neurological sciences (01-10-2018)“…Neurosarcoidosis is relatively rare and has diverse manifestations. The clinical characteristics, diagnosis, treatment, and outcome for neurosarcoidosis in…”
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Generation and characterization of a human induced pluripotent stem cell line (XWHNi001-A) derived from an Alzheimer's disease patient with mutation in the APP gene
Published in Stem cell research (01-04-2022)“…Mutations in the APP gene are popularly known as the second cause trigger the familial Alzheimer's disease (AD). We generated a human induced pluripotent stem…”
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Efficacy and Safety of Donepezil in Chinese Patients with Severe Alzheimer's Disease: A Randomized Controlled Trial
Published in Journal of Alzheimer's disease (01-01-2017)“…Donepezil has been used worldwide for the treatment of severe Alzheimer's disease (AD). Whether it is also appropriate for severe AD in Chinese patients…”
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Validation of the Delayed Matching-to-Sample Task 48 (DMS48) in Elderly Chinese
Published in Journal of Alzheimer's disease (01-01-2018)“…Delayed Matching-to-Sample Task 48 (DMS48), a brief tool measuring visual recognition memory, is valid to identify the early stage of Alzheimer's disease (AD)…”
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Culture Effects on the Chinese Version Boston Naming Test Performance and the Normative Data in the Native Chinese-Speaking Elders in Mainland China
Published in Frontiers in neurology (13-05-2022)“…The Chinese version of Boston Naming Test (BNT-C) is administered in China widely. However, the neuropsychological parameter of BNT-C in native…”
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Generation of induced pluripotent stem cell line (XWHNi002-A) from a female with APP gene mutation
Published in Stem cell research (01-09-2023)“…The β-amyloid precursor protein (APP) is a crucial pathogenic gene linked to Alzheimer's disease (AD). A human induced pluripotent stem cell (iPSC) line was…”
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