Search Results - "Wei, Binqing Q."
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A Second Fatty Acid Amide Hydrolase with Variable Distribution among Placental Mammals
Published in The Journal of biological chemistry (01-12-2006)“…Fatty acid amides constitute a large and diverse class of lipid transmitters that includes the endogenous cannabinoid anandamide and the sleep-inducing…”
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Soft Docking and Multiple Receptor Conformations in Virtual Screening
Published in Journal of medicinal chemistry (07-10-2004)“…Protein conformational change is an important consideration in ligand-docking screens, but it is difficult to predict. A simple way to account for protein…”
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Structure-based Inhibitor Discovery against Adenylyl Cyclase Toxins from Pathogenic Bacteria That Cause Anthrax and Whooping Cough
Published in The Journal of biological chemistry (11-07-2003)“…Edema factor (EF) and CyaA are adenylyl cyclase toxins secreted by pathogenic bacteria that cause anthrax and whooping cough, respectively. Using the structure…”
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A streamlined platform for high-content functional proteomics of primary human specimens
Published in Nature methods (01-09-2005)“…Achieving information content of satisfactory breadth and depth remains a formidable challenge for proteomics. This problem is particularly relevant to the…”
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Testing a Flexible-receptor Docking Algorithm in a Model Binding Site
Published in Journal of molecular biology (09-04-2004)“…Sampling receptor flexibility is challenging for database docking. We consider a method that treats multiple flexible regions of the binding site…”
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A Model Binding Site for Testing Scoring Functions in Molecular Docking
Published in Journal of molecular biology (13-09-2002)“…Prediction of interaction energies between ligands and their receptors remains a major challenge for structure-based inhibitor discovery. Much effort has been…”
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