Search Results - "Wehr, Nancy B"

Small-molecule antioxidant proteome-shields in Deinococcus radiodurans by Daly, Michael J, Gaidamakova, Elena K, Matrosova, Vera Y, Kiang, Juliann G, Fukumoto, Risaku, Lee, Duck-Yeon, Wehr, Nancy B, Viteri, Gabriela A, Berlett, Barbara S, Levine, Rodney L

“…For Deinococcus radiodurans and other bacteria which are extremely resistant to ionizing radiation, ultraviolet radiation, and desiccation, a mechanistic link…”
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Protein carbonylation: avoiding pitfalls in the 2,4-dinitrophenylhydrazine assay by Luo, Shen, Wehr, Nancy B

“…Protein carbonyl content is widely used as both a marker for oxidative stress and a measure of oxidative damage. Widely used methods for determination of…”
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Quantitation of protein on gels and blots by infrared fluorescence of Coomassie blue and Fast Green by Luo, Shen, Wehr, Nancy B., Levine, Rodney L.

“…Coomassie blue staining of gels and blots is commonly employed for detection and quantitation of proteins by densitometry. We found that Coomassie blue or Fast…”
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Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes by Curtis, Christina, Landis, Gary N, Folk, Donna, Wehr, Nancy B, Hoe, Nicholas, Waskar, Morris, Abdueva, Diana, Skvortsov, Dmitriy, Ford, Daniel, Luu, Allan, Badrinath, Ananth, Levine, Rodney L, Bradley, Timothy J, Tavaré, Simon, Tower, John

“…Several interventions increase lifespan in model organisms, including reduced insulin/insulin-like growth factor-like signaling (IIS), FOXO transcription…”
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Iron-Dependent Oxidation, Ubiquitination, and Degradation of Iron Regulatory Protein 2: Implications for Degradation of Oxidized Proteins by Iwai, Kazuhiro, Drake, Steven K., Wehr, Nancy B., Weissman, Allan M., LaVaute, Timothy, Minato, Nagahiro, Klausner, Richard D., Levine, Rodney L., Rouault, Tracey A.

“…The ability of iron to catalyze formation of reactive oxygen species significantly contributes to its toxicity in cells and animals. Iron uptake and…”
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Carbonic Anhydrase III Is Not Required in the Mouse for Normal Growth, Development, and Life Span by Kim, Geumsoo, Lee, Tae-Hoon, Wetzel, Petra, Geers, Cornelia, Robinson, Mary Ann, Myers, Timothy G., Owens, Jennie W., Wehr, Nancy B., Eckhaus, Michael W., Gros, Gerolf, Wynshaw-Boris, Anthony, Levine, Rodney L.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Wanted and wanting: Antibody against methionine sulfoxide by Wehr, Nancy B., Levine, Rodney L.

“…Methionine residues in protein can be oxidized by reactive oxygen or nitrogen species to generate methionine sulfoxide. This covalent modification has been…”
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Quantitation of protein carbonylation by dot blot by Wehr, Nancy B., Levine, Rodney L.

“…Protein carbonylation is the most commonly used measure of oxidative modification of proteins. It is frequently measured spectrophotometrically or…”
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Methionine oxidation and aging by Stadtman, Earl R., Van Remmen, Holly, Richardson, Arlan, Wehr, Nancy B., Levine, Rodney L.

“…It is well established that many amino acid residues of proteins are susceptible to oxidation by various forms of reactive oxygen species (ROS), and that…”
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Group B Streptococcal Phospholipid Causes Pulmonary Hypertension by Curtis, Jerri, Kim, Geumsoo, Wehr, Nancy B., Levine, Rodney L.

“…Group B Streptococcus is the most common cause of bacterial infection in the newborn. Infection in many cases causes persistent pulmonary hypertension, which…”
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Treatment with the reactive oxygen species scavenger EUK-207 reduces lung damage and increases survival during 1918 influenza virus infection in mice by Kash, John C., Xiao, Yongli, Davis, A.Sally, Walters, Kathie-Anne, Chertow, Daniel S., Easterbrook, Judith D., Dunfee, Rebecca L., Sandouk, Aline, Jagger, Brett W., Schwartzman, Louis M., Kuestner, Rolf E., Wehr, Nancy B., Huffman, Karl, Rosenthal, Rosalind A., Ozinsky, Adrian, Levine, Rodney L., Doctrow, Susan R., Taubenberger, Jeffery K.

“…The 1918 influenza pandemic caused over 40 million deaths worldwide, with 675,000 deaths in the United States alone. Studies in several experimental animal…”
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Response to Dr. Moskovitz by Wehr, Nancy B, Levine, Rodney L

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Erratum to: Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes by Curtis, Christina, Landis, Gary N, Folk, Donna, Wehr, Nancy B, Hoe, Nicholas, Waskar, Morris, Abdueva, Diana, Skvortsov, Dmitriy, Ford, Daniel, Luu, Allan, Badrinath, Ananth, Levine, Rodney L, Bradley, Timothy J, Tavaré, Simon, Tower, John

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Identification of Oxidant-Sensitive Proteins:  TNF-α Induces Protein Glutathiolation by Sullivan, Daniel M, Wehr, Nancy B, Fergusson, Maria M, Levine, Rodney L, Finkel, Toren

“…Reactive oxygen species are thought to play a role in a variety of physiologic and pathophysiological processes. One possible mediator of oxidant effects at…”
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Quantification of protein carbonylation by Wehr, Nancy B, Levine, Rodney L

“…Protein carbonylation is the most commonly used measure of oxidative modification of proteins. It is most often measured spectrophotometrically or…”
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Iron regulatory protein 2 as iron sensor. Iron-dependent oxidative modification of cysteine by Kang, Dae-Kyung, Jeong, Jinsook, Drake, Steven K, Wehr, Nancy B, Rouault, Tracey A, Levine, Rodney L

“…Iron regulatory protein 2 coordinates cellular regulation of iron metabolism by binding to iron responsive elements in mRNA. The protein is synthesized…”
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Assessment of Skin Carbonyl Content as a Noninvasive Measure of Biological Age by Richert, Susann, Wehr, Nancy B., Stadtman, Earl R., Levine, Rodney L.

“…The oxidative modification of proteins by reactive species, especially reactive oxygen species, is implicated in the etiology or progression of a panoply of…”
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Iron Regulatory Protein 2 as Iron Sensor by Kang, Dae-Kyung, Jeong, Jinsook, Drake, Steven K., Wehr, Nancy B., Rouault, Tracey A., Levine, Rodney L.

“…Iron regulatory protein 2 coordinates cellular regulation of iron metabolism by binding to iron responsive elements in mRNA. The protein is synthesized…”
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Numerous proteins in Mammalian cells are prone to iron-dependent oxidation and proteasomal degradation by Drake, Steven K, Bourdon, Emmanuel, Wehr, Nancy B, Levine, Rodney L, Backlund, Peter S, Yergey, Alfred L, Rouault, Tracey A

“…The mechanisms that underlie iron toxicity in cells and organisms are poorly understood. Previous studies of regulation of the cytosolic iron sensor,…”
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Corrigendum to “Quantitation of protein carbonylation by dot blot” [Anal. Biochem. 423 (2012) 241–245] by Wehr, Nancy B., Levine, Rodney L.

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