Search Results - "Wegmann, KW"

Blocking OX-40/OX-40 Ligand Interaction In Vitro and In Vivo Leads to Decreased T Cell Function and Amelioration of Experimental Allergic Encephalomyelitis by Weinberg, Andrew D, Wegmann3, Keith W, Funatake, Castle, Whitham, Ruth H

“…The OX-40R is a member of the TNF receptor family and is expressed primarily on activated CD4+ T cells. When the OX-40R is engaged by the OX-40 ligand…”
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Identification of myocarditogenic peptides derived from cardiac myosin capable of inducing experimental allergic myocarditis in the Lewis rat. The utility of a class II binding motif in selecting self-reactive peptides by Wegmann, KW, Zhao, W, Griffin, AC, Hickey, WF

“…Cardiac myosin (CM) has been implicated as an autoantigen in the induction of experimental allergic myocarditis (EAM). At the present time no myocarditogenic…”
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Experimental autoimmune insulitis. Induction by T lymphocytes specific for a peptide of proinsulin by Griffin, AC, Zhao, W, Wegmann, KW, Hickley, WF

“…Type I diabetes, an autoimmune disease that occurs in humans and animals, is characterized by the destruction of insulin-secreting islet beta-cells of the…”
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Identification and Characterization of the Antigen Presenting Cell in Rat Autoimmune Myocarditis: Evidence of Bone Marrow Derivation and Non-requirement for MHC Class I Compatibility with Pathogenic T Cells by Ratcliffe, Nora R, Wegmann, Keith W, Zhao, Richard W, Hickey, William F

“…In the rat, autoimmune myocarditis can be produced by the infusion of activated myosin peptide specific, CD4+, class II restricted, effector T cells. Whether…”
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Identification of an N-terminally acetylated encephalitogenic epitope in myelin proteolipid apoprotein for the Lewis rat by Zhao, W, Wegmann, KW, Trotter, JL, Ueno, K, Hickey, WF

“…Proteolipid apoprotein (PLP) is a major component of the central nervous system myelin. As such, it is capable of inducing experimental allergic…”
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Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element by Hinrichs, D J, Wegmann, K W, Dietsch, G N

“…The adoptive transfer of clinical and histopathologic signs of experimental allergic encephalomyelitis (EAE) requires MHC compatibility between cell donor and…”
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Generation of anti-AKR/gross murine leukemia virus cytotoxic T lymphocytes (CTL). An analysis of precursor CTL frequencies in the AKR.H-2b and C57BL/6 mouse strains by Wegmann, KW, Rich, RF, Green, WR

“…C57BL/6 mice, after immunization and secondary in vitro restimulation with AKR/Gross murine leukemia virus (MuLV)-induced tumors, generate AKR/Gross…”
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Mechanism of nonresponsiveness to AKR/Gross leukemia virus in AKR.H- 2b:Fv-1b mice. An analysis of precursor cytotoxic T lymphocyte frequencies in young versus moderately aged mice by Wegmann, KW, McMaster, JS, Green, WR

“…As young adult AKR.H-2b:Fv-1b mice reach about 9 wk of age, they begin to develop a nonresponsiveness to AKR/Gross leukemia virus. Unlike young mice that are…”
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Recipient contributions to serial passive transfer of experimental allergic encephalomyelitis by Wegmann, KW, Hinrichs, DJ

“…EAE can be adoptively transferred into normal recipients by the transfer of BP-specific EAE effector cells. After cell transfer, a series of ill-defined events…”
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The influence of cyclosporin A on the development of actively induced and passively transferred experimental allergic encephalomyelitis by Hinrichs, D J, Wegmann, K W, Peters, B A

“…The immunosuppressive effects of cyclosporin A (CsA) were tested on actively induced and passively transferred experimental allergic encephalomyelitis (EAE)…”
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