Search Results - "Wegierski, Tomasz"

Loss of Stim2 in zebrafish induces glaucoma-like phenotype by Baranykova, Sofiia, Gupta, Rishikesh Kumar, Kajdasz, Arkadiusz, Wasilewska, Iga, Macias, Matylda, Szybinska, Aleksandra, Węgierski, Tomasz, Nahia, Karim Abu, Mondal, Shamba S., Winata, Cecilia L., Kuźnicki, Jacek, Majewski, Lukasz

“…Calcium is involved in vision processes in the retina and implicated in various pathologies, including glaucoma. Rod cells rely on store-operated calcium entry…”
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TRPP2 and TRPV4 form a polymodal sensory channel complex by Köttgen, Michael, Buchholz, Björn, Garcia-Gonzalez, Miguel A, Kotsis, Fruzsina, Fu, Xiao, Doerken, Mara, Boehlke, Christopher, Steffl, Daniel, Tauber, Robert, Wegierski, Tomasz, Nitschke, Roland, Suzuki, Makoto, Kramer-Zucker, Albrecht, Germino, Gregory G, Watnick, Terry, Prenen, Jean, Nilius, Bernd, Kuehn, E. Wolfgang, Walz, Gerd

“…The primary cilium has evolved as a multifunctional cellular compartment that decorates most vertebrate cells. Cilia sense mechanical stimuli in various…”
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Molecular anatomy of the thalamic complex and the underlying transcription factors by Nagalski, Andrzej, Puelles, Luis, Dabrowski, Michal, Wegierski, Tomasz, Kuznicki, Jacek, Wisniewska, Marta B.

“…Thalamocortical loops have been implicated in the control of higher-order cognitive functions, but advances in our understanding of the molecular underpinnings…”
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Tyrosine Phosphorylation Modulates the Activity of TRPV4 in Response to Defined Stimuli by Wegierski, Tomasz, Lewandrowski, Urs, Müller, Barbara, Sickmann, Albert, Walz, Gerd

“…Src family tyrosine kinases (SFKs) regulate the function of several transient receptor potential (TRP) family members, yet their role in the regulation of the…”
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The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels by Wegierski, Tomasz, Hill, Kerstin, Schaefer, Michael, Walz, Gerd

“…TRPV4 is a widely expressed member of the transient receptor potential (TRP) family that facilitates Ca2+ entry into nonexcitable cells. TRPV4 is activated by…”
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TRPP2 channels regulate apoptosis through the Ca2+ concentration in the endoplasmic reticulum by Wegierski, Tomasz, Steffl, Daniel, Kopp, Christoph, Tauber, Robert, Buchholz, Björn, Nitschke, Roland, Kuehn, E Wolfgang, Walz, Gerd, Köttgen, Michael

“…Ca 2+ is an important signalling molecule that regulates multiple cellular processes, including apoptosis. Although Ca 2+ influx through transient receptor…”
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OS-9 Regulates the Transit and Polyubiquitination of TRPV4 in the Endoplasmic Reticulum by Wang, Yan, Fu, Xiao, Gaiser, Stephanie, Köttgen, Michael, Kramer-Zucker, Albrecht, Walz, Gerd, Wegierski, Tomasz

“…Transient receptor potential (TRP) proteins constitute a family of cation-permeable channels that are formed by homo- or heteromeric assembly of four subunits…”
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Regulation of ciliary polarity by the APC/C by Ganner, Athina, Lienkamp, Soeren, Schäfer, Tobias, Romaker, Daniel, Wegierski, Tomasz, Park, Tae Joo, Spreitzer, Stefan, Simons, Matias, Gloy, Joachim, Kim, Emily, Wallingford, John B, Walz, Gerd

“…Planar cell polarity signaling controls a variety of polarized cell behaviors. In multiciliated Xenopus epidermal cells, recruitment of Dishevelled (Dvl) to…”
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PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation by Gao, Hongyu, Wang, Yan, Wegierski, Tomasz, Skouloudaki, Kassiani, Pütz, Michael, Fu, Xiao, Engel, Christina, Boehlke, Christopher, Peng, Hongquan, Kuehn, E. Wolfgang, Kim, Emily, Kramer-Zucker, Albrecht, Walz, Gerd

“…Autosomal dominant polycystic liver disease (PCLD) is caused by mutations of either PRKCSH or Sec63, two proteins associated with the endoplasmic reticulum…”
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Neuronal calcium signaling via store-operated channels in health and disease by Wegierski, Tomasz, Kuznicki, Jacek

“…[Display omitted] •Neuronal store-operated calcium entry (nSOCE) was detected in multiple brain areas.•nSOCE is required for neuronal physiology.•Dysregulation…”
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Knockdown of amyloid precursor protein increases calcium levels in the endoplasmic reticulum by Gazda, Kinga, Kuznicki, Jacek, Wegierski, Tomasz

“…Familial Alzheimer’s disease (AD) is caused by mutations in the genes that encode amyloid precursor protein (APP) and presenilins. Disturbances in calcium…”
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Microscopic analysis of Orai-mediated store-operated calcium entry in cells with experimentally altered levels of amyloid precursor protein by Wegierski, Tomasz, Gazda, Kinga, Kuznicki, Jacek

“…Familial Alzheimer's disease (FAD)-causing mutations in presenilins were shown to alter intracellular calcium dynamics, including store-operated calcium entry…”
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Identification of a Protein Kinase C-dependent phosphorylation site involved in sensitization of TRPV4 channel by Peng, Hongquan, Lewandrowski, Urs, Müller, Barbara, Sickmann, Albert, Walz, Gerd, Wegierski, Tomasz

“…Transient Receptor Potential (TRP) proteins are non-selective cation channels performing diverse cellular functions. TRPV1 and TRPV4, two calcium-permeable…”
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TENT5 cytoplasmic noncanonical poly(A) polymerases regulate the innate immune response in animals by Liudkovska, Vladyslava, Krawczyk, Paweł S, Brouze, Aleksandra, Gumińska, Natalia, Wegierski, Tomasz, Cysewski, Dominik, Mackiewicz, Zuzanna, Ewbank, Jonathan J, Drabikowski, Krzysztof, Mroczek, Seweryn, Dziembowski, Andrzej

“…Innate immunity is the first line of host defense against pathogens. Here, through global transcriptome and proteome analyses, we uncover that newly described…”
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Bms1p, a G-domain-containing protein, associates with Rcl1p and is required for 18S rRNA biogenesis in yeast by WEGIERSKI, TOMASZ, BILLY, ERIC, NASR, FAHD, FILIPOWICZ, WITOLD

“…Maturation of 18S rRNA and biogenesis of the 40S ribosomes in yeast requires a large number of trans-acting factors, including the U3 small nucleolar…”
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Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis by Billy, E, Wegierski, T, Nasr, F, Filipowicz, W

“…RNA 3′‐terminal phosphate cyclases are evolutionarily conserved enzymes catalysing conversion of the 3′‐terminal phosphate in RNA to the 2′,3′‐cyclic…”
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TRPP2 channels regulate apoptosis through the Ca 2+ concentration in the endoplasmic reticulum by Köttgen, Michael, Wegierski, Tomasz, Steffl, Daniel, Kopp, Christoph, Tauber, Robert, Buchholz, Björn, Nitschke, Roland, Kuehn, E Wolfgang, Walz, Gerd

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TRPP2 and TRPV4 form a polymodal sensory channel complex by Köttgen, Michael, Buchholz, Björn, Garcia-Gonzalez, Miguel A., Kotsis, Fruzsina, Fu, Xiao, Doerken, Mara, Boehlke, Christopher, Steffl, Daniel, Tauber, Robert, Wegierski, Tomasz, Nitschke, Roland, Suzuki, Makoto, Kramer-Zucker, Albrecht, Germino, Gregory G., Watnick, Terry, Prenen, Jean, Nilius, Bernd, Kuehn, E. Wolfgang, Walz, Gerd

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Microscopic imaging of calcium ions with genetically encoded calcium indicators by Gazda, Kinga, Bazała, Michal, Węgierski, Tomasz

“…Calcium is a second messenger that plays a key role in various cellular processes. Monitoring calcium levels is a prerequisite to their understanding. The…”
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Yeast nuclear PET127 gene can suppress deletions of the SUV3 or DSS1 genes: an indication of a functional interaction between 3' and 5' ends of mitochondrial mRNAs by Wegierski, T, Dmochowska, A, Jabłonowska, A, Dziembowski, A, Bartnik, E, Stepień, P P

“…Saccharomyces cerevisiae nuclear genes SUV3 and DSS1 encode putative RNA helicase and RNase II, respectively, which are subunits of the mitochondrial…”
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