Search Results - "Wegenka, Ursula"

IL-20: Biological functions mediated through two types of receptor complexes by Wegenka, Ursula Maria

“…Abstract IL-20 was discovered 10 years ago as a new member of the IL-10 family of cytokines. IL-20 shares the highest amino-acid sequence identity with IL-10,…”
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The murine liver is a potential target organ for IL-19, IL-20 and IL-24: Type I Interferons and LPS regulate the expression of IL-20R2 by Wegenka, Ursula Maria, Dikopoulos, Nektarios, Reimann, Jörg, Adler, Guido, Wahl, Christian

“…Background/Aims The biological functions of the recently discovered IL-10-related cytokines IL-19, IL-20, IL-22, IL-24 and their receptors IL-20R1, IL-20R2 and…”
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CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potential by Radulovic, Katarina, Manta, Calin, Rossini, Valerio, Holzmann, Karlheinz, Kestler, Hans A, Wegenka, Ursula Maria, Nakayama, Toshinori, Niess, Jan Hendrik

“…CD69 is highly expressed by lymphocytes at mucosal surfaces. We aimed to investigate the role of CD69 in mucosal immune responses. The expression of CD69 by…”
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IL-22-Dependent Attenuation of T Cell-Dependent (ConA) Hepatitis in Herpes Virus Entry Mediator Deficiency by Wahl, Christian, Wegenka, Ursula Maria, Leithauser, Frank, Schirmbeck, Reinhold, Reimann, Jorg

“…Coinhibitors and costimulators control intrahepatic T cell responses that trigger acute hepatitis. We used the ConA-induced hepatitis model in the mouse to…”
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IL-20 Receptor 2 Signaling Down-Regulates Antigen-Specific T Cell Responses by Wahl, Christian, Muller, Werner, Leithauser, Frank, Adler, Guido, Oswald, Franz, Reimann, Jorg, Schirmbeck, Reinhold, Seier, Anne, Weiss, Johannes Martin, Prochnow, Blair, Wegenka, Ursula Maria

“…The recently described cytokines IL-19, IL-20, and IL-24 share structural homology with IL-10 and are therefore classified as members of the IL-10 family of…”
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Association of Transcription Factor APRF and Protein Kinase Jak1 with the Interleukin-6 Signal Transducer gp130 by Lütticken, Claudia, Wegenka, Ursula M., Yuan, Juping, Buschmann, Jan, Schindler, Chris, Ziemiecki, Andrew, Harpur, Ailsa G., Wilks, Andrew F., Yasukawa, Kiyoshi, Taga, Tetsuya, Kishimoto, Tadamitsu, Barbieri, Giovanna, Pellegrini, Sandra, Sendtner, Michael, Heinrich, Peter C., Horn, Friedemann

“…Interleukin-6 (IL-6), leukemia inhibitory factor, oncostatin M, interleukin-11, and ciliary neurotrophic factor bind to receptor complexes that share the…”
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Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level by Wegenka, U M, Buschmann, J, Luetticken, C, Heinrich, P C, Horn, F

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Priming Protective CD8 T Cell Immunity by DNA Vaccines Encoding Chimeric, Stress Protein-Capturing Tumor-Associated Antigen by Schirmbeck, Reinhold, Riedl, Petra, Kupferschmitt, Mark, Wegenka, Ursula, Hauser, Hansjorg, Rice, Jason, Kroger, Andrea, Reimann, Jorg

“…DNA vaccines encoding heat shock protein (hsp)-capturing, chimeric peptides containing antigenic determinants of the tumor-associated Ag (TAA) gp70 (an…”
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E2F-1 overexpression in cardiomyocytes induces downregulation of p21(CIP1) and p27(KIP1) and release of active cyclin-dependent kinases in the presence of insulin-like growth factor I by Rudiger von Harsdorf, Hauck, Ludger, Mehrhof, Felix, Wegenka, Ursula

“…The heart is a postmitotic organ unable to regenerate after injury. The mechanisms controlling cell cycle arrest in cardiomyocytes are still unknown…”
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Recently primed CD8+ T cells entering the liver induce hepatocytes to interact with naïve CD8+ T cells in the mouse by Dikopoulos, Nektarios, Wegenka, Ursula, Kröger, Andrea, Hauser, Hansjörg, Schirmbeck, Reinhold, Reimann, Jörg

“…Large number of T cells traffic through the liver. In order to examine the effects of such traffic on the phenotype of hepatocytes, we vaccinated mice using…”
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The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family by WEGENKA, U. M, LÜTTICKEN, C, BUSCHMANN, J, JUPING YUAN, LOTTSPEICH, F, MÜLLER-ESTERL, W, SCHINDLER, C, ROEB, E, HEINRICH, P. C, HORN, F

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The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements by Yuan, J, Wegenka, U M, Lütticken, C, Buschmann, J, Decker, T, Schindler, C, Heinrich, P C, Horn, F

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Cytokines and growth factors signal through tyrosine phosphorylation of a family of related transcription factors by Rothman, P, Kreider, B, Azam, M, Levy, D, Wegenka, U, Eilers, A, Decker, T, Horn, F, Kashleva, H, Ihle, J

“…The ability of cytokines to activate distinct but overlapping sets of genes defines their characteristic biological response. We now show that IFN gamma, IL-3,…”
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E2F-1 Overexpression in Cardiomyocytes Induces Downregulation of p21 CIP1 and p27 KIP1 and Release of Active Cyclin-Dependent Kinases in the Presence of Insulin-Like Growth Factor I by von Harsdorf, Rüdiger, Hauck, Ludger, Mehrhof, Felix, Wegenka, Ursula, Cardoso, M. Cristina, Dietz, Rainer

“…Abstract —The heart is a postmitotic organ unable to regenerate after injury. The mechanisms controlling cell cycle arrest in cardiomyocytes are still unknown…”
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E2F-1 Overexpression in Cardiomyocytes Induces Downregulation of p21CIP1 and p27KIP1 and Release of Active Cyclin-Dependent Kinases in the Presence of Insulin-Like Growth Factor I by von Harsdorf, Rüdiger, Hauck, Ludger, Mehrhof, Felix, Wegenka, Ursula, Cardoso, M Cristina, Dietz, Rainer

“…The heart is a postmitotic organ unable to regenerate after injury. The mechanisms controlling cell cycle arrest in cardiomyocytes are still unknown…”
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Membrane-bound and soluble interleukin-6 receptor: studies on structure, regulation of expression, and signal transduction by Heinrich, P C, Graeve, L, Rose-John, S, Schneider-Mergener, J, Dittrich, E, Erren, A, Gerhartz, C, Hemann, U, Lütticken, C, Wegenka, U

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Association of transcription factor APRF and protein kinase Jak1 with the interlukin-6 signal transducer gp130 by Lutticken, Claudia, Wegenka, Ursula M, Yuan, Juping, Buschmann, Jan, Schindler, Chris, Ziemiecki, Andrew, Harpur, Ailsa G, Wilks, Andrew F, Yasukawa, Kiyoshi, Taga, Tetsuya, Kishimoto, Tadamitsu, Barbieri, Giovanna, Pellegrini, Sandra, Sendtner, Michael, Heinrich, Peter C, Horn, Friedemann

“…Interleukin-6 (IL-6), leukemia inhibitory factor, oncostatin M, interleukin-11, and ciliary neurotrophic factor bind to receptor complexes that share the…”
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Acute-Phase Response Factor, a Nuclear Factor Binding to Acute-Phase Response Elements, is Rapidly Activated by Interleukin-6 at the Posttranslational Level by Wegenka, Ursula M., Buschmann, Jan, Lütticken, Claudia, Heinrich, Peter C., Horn, Friedemann

“…Interleukin-6 (IL-6) is known to be a major mediator of the acute-phase response in liver. We show here that IL-6 triggers the rapid activation of a nuclear…”
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The Signalling Pathways of Interleukin-6 and Gamma Interferon Converge by the Activation of Different Transcription Factors Which Bind to Common Responsive DNA Elements by Yuan, Juping, Wegenka, Ursula M., Lütticken, Claudia, Buschmann, Jan, Decker, Thomas, Schindler, Chris, Heinrich, Peter C., Horn, Friedemann

“…Interleukin-6 (IL-6) and gamma interferon (IFN-γ) induce a partially overlapping set of genes, including the genes for interferon regulatory factor 1 (IRF-1),…”
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Gene expression of the high molecular weight proteinase inhibitor alpha 2-macroglobulin by Krause, E, Wegenka, U, Möller, C, Horn, F, Heinrich, P C

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