Search Results - "Wegener, Amelie"
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Transdifferentiation of Human Circulating Monocytes Into Neuronal-Like Cells in 20 Days and Without Reprograming
Published in Frontiers in molecular neuroscience (19-09-2018)“…Despite progress, our understanding of psychiatric and neurological illnesses remains poor, at least in part due to the inability to access neurons directly…”
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Gain of Olig2 function in oligodendrocyte progenitors promotes remyelination
Published in Brain (London, England : 1878) (01-01-2015)“…The basic helix-loop-helix transcription factor Olig2 is a key determinant for the specification of neural precursor cells into oligodendrocyte progenitor…”
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Redefining the Progression of Lineage Segregations during Mammalian Embryogenesis by Clonal Analysis
Published in Developmental cell (01-09-2009)“…Clonal lineage information is fundamental in revealing cell fate choices. Using genetic single-cell labeling in utero, we investigated lineage segregations…”
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Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination
Published in Nucleic acids research (18-09-2020)“…Schwann cells are the nerve ensheathing cells of the peripheral nervous system. Absence, loss and malfunction of Schwann cells or their myelin sheaths lead to…”
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Elevated in vivo levels of a single transcription factor directly convert satellite glia into oligodendrocyte-like cells
Published in PLoS genetics (01-02-2015)“…Oligodendrocytes are the myelinating glia of the central nervous system and ensure rapid saltatory conduction. Shortage or loss of these cells leads to severe…”
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PW1 gene/paternally expressed gene 3 (PW1/Peg3) identifies multiple adult stem and progenitor cell populations
Published in Proceedings of the National Academy of Sciences - PNAS (12-07-2011)“…A variety of markers are invaluable for identifying and purifying stem/progenitor cells. Here we report the generation of a murine reporter line driven by Pw1…”
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Sp2 is the only glutamine‐rich specificity protein with minor impact on development and differentiation in myelinating glia
Published in Journal of neurochemistry (01-01-2017)“…Oligodendrocytes and Schwann cells are the myelinating glia of the vertebrate nervous system and by generation of myelin sheaths allow rapid saltatory…”
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Gain‐of‐Function of Olig Transcription Factors Enhances Oligodendrogenesis and Myelination
Published in Stem cells (Dayton, Ohio) (01-09-2010)“…The basic helix‐loop‐helix transcription factors Olig1 and Olig2 are required for oligodendrocyte specification and differentiation during central nervous…”
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Elevated In Vivo Levels of a Single Transcription Factor Directly Convert Satellite Glia into Oligodendrocyte-like Cells: e1005008
Published in PLoS genetics (01-02-2015)“…Oligodendrocytes are the myelinating glia of the central nervous system and ensure rapid saltatory conduction. Shortage or loss of these cells leads to severe…”
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Loss of the KN Motif and AnKyrin Repeat Domain 1 (KANK1) Leads to Lymphoid Compartment Dysregulation in Murine Model
Published in Genes (01-10-2023)“…The KN Motif and AnKyrin Repeat Domain 1 (KANK1) is proposed as a tumour suppressor gene, as its expression is reduced or absent in several types of tumour…”
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03-P017 Common progenitors for neurectoderm and mesoderm are present from gastrulation to tail bud stage in mouse
Published in Mechanisms of development (01-08-2009)Get full text
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