Search Results - "Weg, Sander M van de"

Lowering Low-Density Lipoprotein Particles in Plasma Using Dextran Sulphate Co-Precipitates Procoagulant Extracellular Vesicles by Wang, Jiong-Wei, Zhang, Ya-Nan, Sze, Siu Kwan, van de Weg, Sander M, Vernooij, Flora, Schoneveld, Arjan H, Tan, Sock-Hwee, Versteeg, Henri H, Timmers, Leo, Lam, Carolyn S P, de Kleijn, Dominique P V

“…Plasma extracellular vesicles (EVs) are lipid membrane vesicles involved in several biological processes including coagulation. Both coagulation and lipid…”
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Complement 5a Receptor deficiency does not influence adverse cardiac remodeling after pressure-overload in mice by de Haan, Judith J., Bosch, Lena, Borgman, Anouska, Bastemeijer, Marissa, Brans, Maike A. D., van de Weg, Sander M., de Kleijn, Dominique P. V., Sluijter, Joost P. G., el Azzouzi, Hamid, de Jager, Saskia C. A.

“…Hypertension is one of the most common risk factors for the development heart failure in the general population. Inflammation plays a central role in this…”
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Leukocyte-Associated Immunoglobulin-like Receptor-1 is regulated in human myocardial infarction but its absence does not affect infarct size in mice by Ellenbroek, Guilielmus H. J. M., de Haan, Judith J., van Klarenbosch, Bas R., Brans, Maike A. D., van de Weg, Sander M., Smeets, Mirjam B., de Jong, Sanne, Arslan, Fatih, Timmers, Leo, Goumans, Marie-José T. H., Hoefer, Imo E., Doevendans, Pieter A., Pasterkamp, Gerard, Meyaard, Linde, de Jager, Saskia C. A.

“…Heart failure after myocardial infarction (MI) depends on infarct size and adverse left ventricular (LV) remodelling, both influenced by the inflammatory…”
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High Levels of (Un)Switched Memory B Cells Are Associated With Better Outcome in Patients With Advanced Atherosclerotic Disease by Meeuwsen, John A. L., Duijvenvoorde, Amerik, Gohar, Aisha, Kozma, Maria O., Weg, Sander M., Gijsberts, Crystel M., Haitjema, Saskia, Björkbacka, Harry, Fredrikson, Gunilla N., Borst, Gert J., Ruijter, Hester M., Pasterkamp, Gerard, Binder, Christoph J., Hoefer, Imo E., Jager, Saskia C. A.

“…Background Atherosclerosis is an inflammatory lipid disorder and the main underlying pathology of acute ischemic events. Despite a vast amount of data from…”
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Extracellular vesicle-derived CD14 is independently associated with the extent of cardiovascular disease burden in patients with manifest vascular disease by Vrijenhoek, Joyce EP, Pasterkamp, Gerard, Moll, Frans L, Borst, Gert Jan de, Bots, Michiel L, Catanzariti, Louise, Weg, Sander M van de, Kleijn, Dominique PV de, Visseren, Frank LJ, Ruijter, Hester M Den

“…Background In patients with established cardiovascular disease, high levels of the extracellular vesicle (EV)-derived proteins cystatin C, CD14, and…”
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Leukotriene B4 levels in human atherosclerotic plaques and abdominal aortic aneurysms by van den Borne, Pleunie, van der Laan, Sander W, Bovens, Sandra M, Koole, Dave, Kowala, Mark C, Michael, Laura F, Schoneveld, Arjan H, van de Weg, Sander M, Velema, Evelyn, de Vries, Jean-Paul, de Borst, Gert J, Moll, Frans L, de Kleijn, Dominique P V, Quax, Paul H A, Hoefer, Imo E, Pasterkamp, Gerard

“…Leukotriene B4 (LTB4) has been associated with the initiation and progression of atherosclerosis and abdominal aortic aneurysm (AAA) formation. However,…”
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Mast cells in human carotid atherosclerotic plaques are associated with intraplaque microvessel density and the occurrence of future cardiovascular events by Willems, Sanne, Vink, Aryan, Bot, Ilze, Quax, Paul H A, de Borst, Gert Jan, de Vries, Jean-Paul P M, van de Weg, Sander M, Moll, Frans L, Kuiper, Johan, Kovanen, Petri T, de Kleijn, Dominique P V, Hoefer, Imo E, Pasterkamp, Gerard

“…Human autopsy, animal, and cell culture studies together have merged in a concept suggesting participation of mast cells (MCs) in the generation of…”
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Circulating CD14+CD16− classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients by Meeuwsen, John A.L., de Vries, Judith J., van Duijvenvoorde, Amerik, van der Velden, Saskia, van der Laan, Sander W., van Koeverden, Ian D., van de Weg, Sander M., de Borst, Gert J., de Winther, Menno P.J., Kuiper, Johan, Pasterkamp, Gerard, Hoefer, Imo E., de Jager, Saskia C.A.

“…Mouse studies have established distinct monocyte subtypes that participate in the process of atherosclerotic lesion formation. The pro-inflammatory Ly6Chigh…”
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Sex Is Associated With the Presence of Atherosclerotic Plaque Hemorrhage and Modifies the Relation Between Plaque Hemorrhage and Cardiovascular Outcome by Vrijenhoek, Joyce E.P, Den Ruijter, Hester M, De Borst, Gert Jan, de Kleijn, Dominique P.V, De Vries, Jean-Paul P.M, Bots, Michiel L, Van de Weg, Sander M, Vink, Aryan, Moll, Frans L, Pasterkamp, Gerard

“…BACKGROUND AND PURPOSE—Plaque hemorrhage (PH) may lead to accelerated progression of atherosclerotic disease. The presence of local PH in the carotid plaque…”
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Serum extracellular vesicle protein levels are associated with acute coronary syndrome by de Hoog, Vince C, Timmers, Leo, Schoneveld, Arjan H, Wang, Jiong-Wei, van de Weg, Sander M, Sze, Siu Kwan, van Keulen, J Karlijn, Hoes, Arno W, den Ruijter, Hester M, de Kleijn, Dominique PV, Mosterd, Arend

“…Aims: Biomarkers are essential in the early detection of acute coronary syndromes (ACS). Serum extracellular vesicles are small vesicles in the plasma…”
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Variants in ALOX5 , ALOX5AP and LTA4H are not associated with atherosclerotic plaque phenotypes: The Athero-Express Genomics Study by van der Laan, Sander W, Foroughi Asl, Hassan, van den Borne, Pleunie, van Setten, Jessica, van der Perk, M.E. Madeleine, van de Weg, Sander M, Schoneveld, Arjan H, de Kleijn, Dominique P.V, Michoel, Tom, Björkegren, Johan L.M, den Ruijter, Hester M, Asselbergs, Folkert W, de Bakker, Paul I.W, Pasterkamp, Gerard

“…Abstract Background The eicosanoid genes ALOX5 , ALOX5AP and LTA4H have been implicated in atherosclerosis. We assessed the impact of common variants in these…”
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Abstract 18348: Total Mast Cell Numbers in Human Carotid Atherosclerotic Plaques and Tryptase Plasma Levels are Predictive for Future Cardiovascular Events by Willems, Sanne, Vink, Aryan, Quax, Paul, de Borst, Gert-Jan, de Vries, Jean-Paul, van de Weg, Sander M, Moll, Frans L, de Kleijn, Dominique P, Hoefer, Imo E, Pasterkamp, Gerard

“…Abstract only Mast cells (MCs) are inflammatory cells known to contribute to the pathogenesis of atherosclerotic disease. Experimental studies have revealed…”
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