Search Results - "Weersma, R"

Environmental factors shaping the gut microbiome in a Dutch population by Gacesa, R., Kurilshikov, A., Vich Vila, A., Sinha, T., Klaassen, M. A. Y., Bolte, L. A., Andreu-Sánchez, S., Chen, L., Collij, V., Hu, S., Dekens, J. A. M., Lenters, V. C., Björk, J. R., Swarte, J. C., Swertz, M. A., Jansen, B. H., Gelderloos-Arends, J., Jankipersadsing, S., Hofker, M., Vermeulen, R. C. H., Sanna, S., Harmsen, H. J. M., Wijmenga, C., Fu, J., Zhernakova, A., Weersma, R. K.

“…The gut microbiome is associated with diverse diseases 1 – 3 , but a universal signature of a healthy or unhealthy microbiome has not been identified, and…”
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The 1000IBD project: multi-omics data of 1000 inflammatory bowel disease patients; data release 1 by Imhann, Floris, Van der Velde, K J, Barbieri, R, Alberts, R, Voskuil, M D, Vich Vila, A, Collij, V, Spekhorst, L M, Van der Sloot, K W J, Peters, V, Van Dullemen, H M, Visschedijk, M C, Festen, E A M, Swertz, M A, Dijkstra, G, Weersma, R K

“…Inflammatory bowel disease (IBD) is a chronic complex disease of the gastrointestinal tract. Patients with IBD can experience a wide range of symptoms, but the…”
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Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis by Festen, E A M, Goyette, P, Scott, R, Annese, V, Zhernakova, A, Lian, J, Lefèbvre, C, Brant, S R, Cho, J H, Silverberg, M S, Taylor, K D, de Jong, D J, Stokkers, P C, Mcgovern, D, Palmieri, O, Achkar, J-P, Xavier, R J, Daly, M J, Duerr, R H, Wijmenga, C, Weersma, R K, Rioux, J D

“…Genetic susceptibility is known to play a large part in the predisposition to the inflammatory bowel diseases (IBDs) known as Crohn's disease (CD) and…”
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Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort by Weersma, R K, Stokkers, P C F, van Bodegraven, A A, van Hogezand, R A, Verspaget, H W, de Jong, D J, van der Woude, C J, Oldenburg, B, Linskens, R K, Festen, E A M, van der Steege, G, Hommes, D W, Crusius, J B A, Wijmenga, C, Nolte, I M, Dijkstra, G

“…Crohn's disease and ulcerative colitis have a complex genetic background. We assessed the risk for both the development and severity of the disease by…”
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Associations with tight junction genes PARD3 and MAGI2 in Dutch patients point to a common barrier defect for coeliac disease and ulcerative colitis by Wapenaar, M C, Monsuur, A J, van Bodegraven, A A, Weersma, R K, Bevova, M R, Linskens, R K, Howdle, P, Holmes, G, Mulder, C J, Dijkstra, G, van Heel, D A, Wijmenga, C

“…Coeliac disease (gluten-sensitive enteropathy; GSE) and inflammatory bowel disease (IBD) are common gastrointestinal disorders. Both display enhanced…”
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Aggravation of fibrin deposition and microthrombus formation within the graft during kidney transplantation by van den Berg, Tamar A. J., van den Heuvel, Marius C., Wiersema-Buist, Janneke, Adelmeijer, Jelle, Nieuwenhuijs-Moeke, Gertrude J., Lisman, Ton, Bakker, Stephan J. L., van Goor, Harry, Pol, Robert A.

“…In kidney transplantation, microthrombi and fibrin deposition may lead to local perfusion disorders and subsequently poor initial graft function. Microthrombi…”
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Gut feelings: the relations between depression, anxiety, psychotropic drugs and the gut microbiome by Brushett, S., Gacesa, R., Vich Vila, A., Brandao Gois, M.F., Andreu-Sánchez, S., Swarte, J.C., Klaassen, M.A.Y., Collij, V., Sinha, T., Bolte, L.A., Wu, J., Swertz, M., de Kroon, M.L.A., Reijneveld, S.A., Wijmenga, C., Weersma, R.K., Fu, J., van Loo, H.M., Kurilshikov, A., Zhernakova, A.

“…The gut microbiome is involved in the bi-directional relationship of the gut - brain axis. As most studies of this relationship are small and do not account…”
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Boron Intake and decreased risk of mortality in kidney transplant recipients by Kremer, Daan, Post, Adrian, Seidel, Ulrike, Huebbe, Patricia, van der Veen, Yvonne, Groothof, Dion, Gomes-Neto, António W., Knobbe, Tim J., Lüersen, Kai, Eisenga, Michele F., Navis, Gerjan J., Rimbach, Gerald, Bakker, Stephan J. L.

“…Purpose In a search for potentially modifiable factors to improve long-term outcome among kidney transplant recipients (KTR), we hypothesized that boron…”
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Genetic Risk Scores Identify Genetic Aetiology of Inflammatory Bowel Disease Phenotypes by Voskuil, M D, Spekhorst, L M, van der Sloot, K W J, Jansen, B H, Dijkstra, G, van der Woude, C J, Hoentjen, F, Pierik, M J, van der Meulen, A E, de Boer, N K H, Löwenberg, M, Oldenburg, B, Festen, E A M, Weersma, R K

“…Abstract Background and Aims Inflammatory bowel disease [IBD] phenotypes are very heterogeneous between patients, and current clinical and molecular…”
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Correction to: The 1000IBD project: multi-omics data of 1000 inflammatory bowel disease patients; data release 1 by Imhann, Floris, Van der Velde, K J, Barbieri, R, Alberts, R, Voskuil, M D, Vila, A Vich, Collij, V, Spekhorst, L M, Van der Sloot, K W J, Peters, V, Van Dullemen, H M, Visschedijk, M C, Festen, E A M, Swertz, M A, Dijkstra, G, Weersma, R K

“…Following publication of the original article [1], the authors…”
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How will insights from genetics translate to clinical practice in inflammatory bowel disease? by Festen, E.A.M., MD, PhD, Weersma, R.K., MD, PhD

“…Abstract Inflammatory bowel disease, consisting of Crohn's disease and ulcerative colitis, is a chronic inflammatory disease of the gut, which arises through…”
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Decreased haemoglobin levels are associated with lower muscle mass and strength in kidney transplant recipients by Vinke, Joanna Sophia J., Wouters, Hanneke J.C.M., Stam, Suzanne P., Douwes, Rianne M., Post, Adrian, Gomes‐Neto, Antonio W., Klauw, Melanie M., Berger, Stefan P., Bakker, Stephan J.L., Annema, C, Bakker, S J L, Berger, S P, Blokzijl, H, Bodewes, F A J A, Boer, M T, Damman, K, De Borst, M H, Diepstra, A, Dijkstra, G, Douwes, R M, Eisenga, M F, Erasmus, M E, Gan, C T, Gomes‐Neto, A W, Hak, E, Hepkema, B G, Klont, F, Knobbe, T J, Kremer, D, Leuvenink, H G D, Lexmond, W S, Meijer, V E, Niesters, H G M, Pelt, L J, Pol, R A, Porte, R J, Ranchor, A V, Sanders, J S F, Schutten, J C, Siebelink, M J, Slart, R H J A, Swarte, J C, Touw, D J, Heuvel, M C, Leer‐Buter, C, Londen, M, Verschuuren, E A M, Vos, M J, Weersma, R K, De Borst, Martin H., Eisenga, Michele F.

“…Background Post‐transplant anaemia and reduced muscle mass and strength are highly prevalent in kidney transplant recipients (KTRs). Decreased haemoglobin…”
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A combination of fecal calprotectin and human beta-defensin 2 facilitates diagnosis and monitoring of inflammatory bowel disease by Gacesa, R., Vich Vila, A., Collij, V., Mujagic, Z., Kurilshikov, A., Voskuil, M.D., Festen, E.A.M., Wijmenga, C., Jonkers, D.M.A.E., Dijkstra, G., Fu, J., Zhernakova, A., Imhann, F., Weersma, R.K.

“…Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) show a large overlap in clinical presentation, which presents diagnostic challenges. As a…”
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Increased incidence of azathioprine‐induced pancreatitis in Crohn's disease compared with other diseases by Weersma, R. K., Peters, F. T. M., Oostenbrug, L. E., Berg, A. P., Haastert, M., Ploeg, R. J., Posthumus, M. D., Homan van der Heide, J. J., Jansen, P. L. M., Dullemen, H. M.

“…Summary Background : Azathioprine is widely used in Crohn's disease. A major drawback is the occurrence of side‐effects, especially acute pancreatitis. Acute…”
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HLA haplotypes in primary sclerosing cholangitis patients of admixed and non‐European ancestry by Henriksen, E. K. K., Viken, M. K., Wittig, M., Holm, K., Folseraas, T., Mucha, S., Melum, E., Hov, J. R., Lazaridis, K. N., Juran, B. D., Chazouillères, O., Färkkilä, M., Gotthardt, D. N., Invernizzi, P., Carbone, M., Hirschfield, G. M., Rushbrook, S. M., Goode, E., Ponsioen, C. Y., Weersma, R. K., Eksteen, B., Yimam, K. K., Gordon, S. C., Goldberg, D., Yu, L., Bowlus, C. L., Franke, A., Lie, B. A., Karlsen, T. H.

“…Primary sclerosing cholangitis (PSC) is strongly associated with several human leukocyte antigen (HLA) haplotypes. Due to extensive linkage disequilibrium and…”
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Investigating obscure gastrointestinal bleeding: capsule endoscopy or double balloon enteroscopy? by WESTERHOF, J, WEERSMA, R. K, KOORNSTRA, J. J

“…The possibility to visualise the small bowel has dramatically improved with the introduction of capsule endoscopy (CE) and double balloon enteroscopy (DBE). CE…”
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Association of Crohn's disease-associated NOD2 variants with intestinal failure requiring small bowel transplantation and clinical outcomes by Janse, M, Weersma, R K, Sudan, D L, Festen, E A M, Wijmenga, C, Dijkstra, G, Mercer, D

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The Impact of Ethnicity and Country of Birth on Inflammatory Bowel Disease Phenotype: a Prospective Cohort Study by Spekhorst, L M, Severs, M, de Boer, N K H, Festen, E A M, Fidder, H H, Hoentjen, F, Imhann, F, de Jong, D J, van der Meulen-de Jong, A E, Pierik, M J, van der Woude, C J, Dijkstra, G, Ponsioen, C Y, Löwenberg, M, Oldenburg, B, Weersma, R K

“…The number of patients with inflammatory bowel disease [IBD], of non-Caucasian descent in Western Europe, is increasing. We aimed to explore the impact of…”
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Review article: inflammatory bowel disease and genetics by WEERSMA, R. K., VAN DULLEMEN, H. M., VAN DER STEEGE, G., NOLTE, I. M., KLEIBEUKER, J. H., DIJKSTRA, G.

“…Summary Introduction  Inflammatory bowel disease (IBD) comprising ulcerative colitis (UC) and Crohn's disease (CD) is multigenic disorder. Tremendous progress…”
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Gene expression profile, pathways, and transcriptional system regulation in indolent systemic mastocytosis by Niedoszytko, M, Oude Elberink, J.N.G, Bruinenberg, M, Nedoszytko, B, de Monchy, J.G.R, te Meerman, G.J, Weersma, R.K, Mulder, A.B, Jassem, E, van Doormaal, J.J

“…To cite this article: Niedoszytko M, Oude Elberink JNG, Bruinenberg M, Nedoszytko B, de Monchy JGR, te Meerman GJ, Weersma RK, Mulder AB, Jassem E, van…”
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