Search Results - "Weerasooriya, Neluka"

A Succinct Route to the Synthesis of Multi-Labelled [D, 13C] α-Methyl Aromatic Ketones by Coumbarides, Gregory Socrates, Eames, Jason, Weerasooriya, Neluka

“…A series of multi-labelled aromatic ketones were efficiently synthesized using a simple deprotonation–deuteriation/alkylation strategy. The yields were high…”
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Investigations into the Bromination of Substituted Phenols using Diethyl Bromomalonate and Diethyl Dibromomalonate by Coumbarides, Gregory Socrates, Dingjan, Marco, Eames, Jason, Weerasooriya, Neluka

“…Substituted 4-bromophenols can be synthesised efficiently by heating the corresponding phenol in either neat diethyl bromomalonate or diethyl dibromomalonate…”
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Recent advances into the enantioselective protonation of prostereogenic enol derivatives by Eames, Jason, Weerasooriya, Neluka

“…We discuss the recent developments into the enantioselective protonation of substituted enol derivatives and comment on the effect that reaction parameters…”
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Investigations into the Regioselective C-Deuteration of Acyclic and Exocyclic Enolates by Eames, Jason, Coumbarides, Gregory S., Suggate, Michael J., Weerasooriya, Neluka

“…Results are reported on the regioselective C‐deuteration of a series of related acyclic and exocyclic enolates derived from substituted aryl ketones. We…”
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Investigations into the enantioselective protonation of enolates derived from 2-methyl-1-tetralone using a chiral diamine ligand by Eames, Jason, Weerasooriya, Neluka

“…The synthesis of enantiomerically enriched (+)-( R)-2-methyl-1-tetralone 1 (up to 47% e.e.) was achieved by enantioselective protonation of an achiral lithium…”
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Investigations into theC-deuteriation of aryl alkyl ketones using urea as a pro-base in the presence of a deuterium donor by Coumbarides, Gregory S., Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

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A Succinct Route to the Synthesis of Multi-Labelled [D, 13C] [alpha]-Methyl Aromatic Ketones by Socrates Coumbarides, Gregory, Eames, Jason, Weerasooriya, Neluka

“…A series of multi-labelled aromatic ketones were efficiently synthesized using a simple deprotonation-deuteriation/alkylation strategy. The yields were high…”
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Investigations on the Efficiency of Regioselective C-Deuteration of Endocyclic Enolates by Eames, Jason, Weerasooriya, Neluka, Coumbarides, Gregory S.

“…Regioselective C‐deuteration of a series of Endocyclic enolates (derived from cyclic aryl ketones) was efficiently achieved by quenching the corresponding…”
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Investigations into the C-deuteriation of aryl alkyl ketones using urea as a pro-base in the presence of a deuterium donor by Coumbarides, Gregory S., Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

“…Results are reported on the regioselective C‐deuteriation of a series of enolates derived from the deprotonation of aryl alkyl ketones using dilithiated urea…”
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Investigations into theC-deuteriation of silyl enol ethers derived from aryl alkyl ketones by Buksha, Svitlana, Coumbarides, Gregory S., Dingjan, Marco, Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

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Probing the regioselectiveC-deuteriation of lithium enolates derived from 2-methyl-tetralone in the presence of substituted tertiary amines by Begum, Mothia, Chavda, Sameer, Coumbarides, Gregory S., Dingan, Marco, Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

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Investigations into the C-deuteriation of silyl enol ethers derived from aryl alkyl ketones by Buksha, Svitlana, Coumbarides, Gregory S., Dingjan, Marco, Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

“…Results are reported on the regioselective C‐deuteriation of a series of silyl enol ethers derived from aryl alkyl ketones using deuterium (D2) gas as the…”
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Investigations into the mechanism of regioselective C-deuteriation of enolates under ‘base-free’ conditions by Coumbarides, Gregory S, Eames, Jason, Weerasooriya, Neluka

“…Regioselective C-deuteriation of enolates was efficiently achieved by quenching the corresponding base-free enolate in the presence of a carbonyl chelating…”
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Investigations into theC-deuteriation of enol acetates derived from aryl alkyl ketones by Buksha, Svitlana, Coumbarides, Gregory S., Dingjan, Marco, Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

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Probing the regioselective C-deuteriation of lithium enolates derived from 2-methyl-tetralone in the presence of substituted tertiary amines by Begum, Mothia, Chavda, Sameer, Coumbarides, Gregory S., Dingan, Marco, Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

“…Results are reported on the regioselective C‐deuteriation of 2‐methyl‐tetralone using a series of D‐sources and tertiary amines as potential mediators. The…”
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Mechanism of enantioselective protonation of an enolate in the presence of a chiral phenolic additive by Eames, Jason, Weerasooriya, Neluka

“…The synthesis of enantiomerically enriched (+)‐(R)‐2‐methyl‐1‐tetralone 1 (up to 29% e.e.) was achieved by enantioselective protonation of the achiral enolate…”
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A practical laboratory route to the synthesis of trideuteriomethyl-[13C] iodide by Coumbarides, Gregory S., Eames, Jason, Weerasooriya, Neluka

“…A practical synthetic laboratory route for the synthesis of trideuteriomethyl‐[13C] iodide (13CD3I) (from tetradeuterio‐[13C]‐methanol and hydriodic acid) is…”
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Investigations into the C-deuteriation of enol acetates derived from aryl alkyl ketones by Buksha, Svitlana, Coumbarides, Gregory S., Dingjan, Marco, Eames, Jason, Suggate, Michael J., Weerasooriya, Neluka

“…Results are reported on the regioselective C‐deuteriation of a series of enol acetates (derived from the aryl alkyl ketones) using molecular deuterium as the…”
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Investigations into the regioselective deuteriation of enolates derived from silyl enol ethers and enolacetates by Coumbarides, Gregory S., Eames, Jason, Weerasooriya, Neluka

“…Results are reported on the regioselective C‐deuteriation of a series of enolates derived from the addition of MeLi to the related enolacetate and silyl enol…”
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Investigations into the regioselective C-deuteriation of enolates using a diisopropylammonium salt by Coumbarides, Gregory S., Eames, Jason, Weerasooriya, Neluka

“…Results are reported on the regioselective C‐deuteriation of 2‐methyl tetralone using a series of diisopropylamine derived D‐sources. The results presented…”
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